Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kazuya Narushima"'
Autor:
Kazuya Narushima, Hiroshi Maeda, Masanari Shiramoto, Yuichi Endo, Satoko Ohtsuka, Hiroaki Nakamura, Yoshinori Nagata, Tatsuo Uchimura, Ayako Kannami, Ryutaro Shimazaki, Masafumi Fukagawa, Tadao Akizawa
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 1, Pp 20-27 (2019)
Abstract Evocalcet is a novel calcimimetic agent for the treatment of secondary hyperparathyroidism (SHPT). This study evaluated the effects of evocalcet on inhibition and induction of cytochrome P450 (CYP) isozymes. Although drug interactions arisin
Externí odkaz:
https://doaj.org/article/1514e29883ab445f9f937630b76834da
Autor:
Hideki Goto, Koji Izutsu, Daisuke Ennishi, Yuko Mishima, Shinichi Makita, Koji Kato, Miyoko Hanaya, Satoshi Hirano, Kazuya Narushima, Takanori Teshima, Hirokazu Nagai, Kenichi Ishizawa
Publikováno v:
International Journal of Hematology. 116:911-921
The selective phosphatidylinositol 3-kinase δ inhibitor zandelisib demonstrated favorable safety and efficacy [objective response rate (ORR) 79%] in patients with B-cell malignancies in a phase 1b study in the US and Switzerland. In this phase 1 dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a9a9f42df753e43b1567ea64f884b2
https://doi.org/10.1007/s12185-022-03450-5
https://doi.org/10.1007/s12185-022-03450-5
Autor:
Michihiro Maemoto, Yuuki Hirata, Shintaro Hosoe, Jun Ouchi, Kazuya Narushima, Emi Akizawa, Yoshiro Tsuji, Hidenori Takada, Arata Yanagisawa, Satoshi Shuto
Publikováno v:
Journal of medicinal chemistry. 65(3)
NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. The inhibition of NaPi2b, responsible for intestinal phosphate absorption, is considered to reduce serum phosphate levels, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4ab3fc3685490ed808778f09e964e2
https://pubmed.ncbi.nlm.nih.gov/35034442
https://pubmed.ncbi.nlm.nih.gov/35034442
Publikováno v:
The Journal of Clinical Pharmacology. 60:58-66
Cutaneous T-cell lymphoma (CTCL) and adult T-cell leukemia/lymphoma (ATL) are rare non-Hodgkin lymphomas commonly expressing C-C chemokine receptor 4 (CCR4). Mogamulizumab is a humanized monoclonal antibody against CCR4 approved in the United States
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18eb657c00a37b414f7f9d3c2a2403af
https://doi.org/10.1002/jcph.1564
https://doi.org/10.1002/jcph.1564
Autor:
Shota Warashina, Nobuhiro Yagi, Kazuya Narushima, Maiko Takahashi, Junko Iwano, Yasuhiro Wada, Hayato Yabuuchi, Takeshi Kuboyama, Yasuyoshi Watanabe, Kentaro Hatanaka, Maki Zouda, Junichi Enokizono, Hidefumi Mukai
Publikováno v:
Journal of Controlled Release. 294:185-194
In vivo biodistribution analyses, especially in tumors, of nucleic acids delivered with nanoparticles are important to develop drug delivery technologies for medical use. We previously developed wrapsome® (WS), an ~100 nm liposomal nanoparticle that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f63d875ab3d2581529d36544107a8fd
https://doi.org/10.1016/j.jconrel.2018.12.006
https://doi.org/10.1016/j.jconrel.2018.12.006
Autor:
Tadao Akizawa, Satoko Ohtsuka, Kazuya Narushima, Hiroaki Nakamura, Yoshinori Nagata, Ryutaro Shimazaki, Tatsuo Uchimura, Masafumi Fukagawa, Hiroshi Maeda, Yuichi Endo, Ayako Kannami, Masanari Shiramoto
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 12, Iss 1, Pp 20-27 (2019)
Clinical and Translational Science, Vol 12, Iss 1, Pp 20-27 (2019)
Evocalcet is a novel calcimimetic agent for the treatment of secondary hyperparathyroidism (SHPT). This study evaluated the effects of evocalcet on inhibition and induction of cytochrome P450 (CYP) isozymes. Although drug interactions arising from re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01826a8c9d487dc41a773d709b4dd9d
https://doi.org/10.1111/cts.12588
https://doi.org/10.1111/cts.12588
Publikováno v:
Journal of clinical pharmacologyReferences. 60(1)
Mogamulizumab is a humanized monoclonal antibody against C-C chemokine receptor 4 approved in the United States for the treatment of patients with relapsed/refractory mycosis fungoides or Sezary syndrome, the most common forms of cutaneous T-cell lym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e38b0a87246ef340c7a40be5965210a
https://pubmed.ncbi.nlm.nih.gov/31840837
https://pubmed.ncbi.nlm.nih.gov/31840837
Publikováno v:
Molecular Pharmacology. 74:42-49
Dietary lipids and fat-soluble micronutrients are solubilized in mixed micelles and absorbed in the small intestine. Based on an assumption that cholesterol and other fat-soluble molecules share a number of transport mechanisms and the fact that Niem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132d8aa7a8c19779f5025428f8291eb5
https://doi.org/10.1124/mol.107.043034
https://doi.org/10.1124/mol.107.043034