CFD Analysis of Effective Human Motion for Whipping Heavy Cream by Hand

Autor: Kazuya Ikeda, Hayato Masuda, Naoko Shirasugi, Sachiko Honda, Takafumi Horie, Naoto Ohmura

Publikováno v: Chemical Engineering Transactions, Vol 75 (2019)

This study observed human motions of whipping conducted by five expert confectionery hygiene mistresses, because mixing performance can be easily estimated by change of physical properties in heavy cream. Mixing state of heavy cream was evaluated by

Externí odkaz: https://doaj.org/article/ef41733f8dbd4ca289bd5172dbee9fb3

Over-Expression of Pancreatic Pituitary Adenylate Cyclase–Activating Polypeptide (PACAP) Aggravates Cerulein-Induced Acute Pancreatitis in Mice

Autor: Ken-ichi Hamagami, Yusuke Sakurai, Norihito Shintani, Naoko Higuchi, Kazuya Ikeda, Hitoshi Hashimoto, Akinobu Suzuki, Hiroshi Kiyama, Akemichi Baba

Publikováno v: Journal of Pharmacological Sciences, Vol 110, Iss 4, Pp 451-458 (2009)

Abstract.: Development of human chronic pancreatitis is associated with intrapancreatic accumulation of pituitary adenylate cyclase–activating polypeptide (PACAP) accompanied with an altered inflammatory response (Michalski et al., Am J Physiol Gas

Externí odkaz: https://doaj.org/article/2b18a706089741fc9e8ad2b2eb59ce64

Scarless genome editing technology and its application to crop improvement.

Autor: Kazuya Ikeda¹ ki@bayspair.com

Publikováno v: Breeding Science. 2024, Vol. 74 Issue 1, p32-36. 5p.

Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder

Autor: Yiran E. Liu, Diane E. Dickel, Robert Aho, Mervenaz Koska, Hannah K. Long, Neha Arora, Licia Selleri, Matthew H. Porteus, Alexander T. Adams, Ian C. Welsh, Ruth M. Williams, Tatjana Sauka-Spengler, James O.J. Davies, Marco Osterwalder, Douglas R. Higgs, Karissa Hansen, Kazuya Ikeda, Axel Visel, Tomek Swigut, Timothy J. Mohun, Jim R. Hughes, Joanna Wysocka

Publikováno v: Long, H K, Osterwalder, M, Welsh, I C, Hansen, K, Davies, J O J, Liu, Y E, Koska, M, Adams, A T, Aho, R, Arora, N, Ikeda, K, Williams, R M, Sauka-Spengler, T, Porteus, M H, Mohun, T, Dickel, D E, Swigut, T, Hughes, J R, Higgs, D R, Visel, A, Selleri, L & Wysocka, J 2020, ' Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder ', Cell Stem Cell, vol. 27, no. 5, pp. 765-783.e14 . https://doi.org/10.1016/j.stem.2020.09.001
Cell Stem Cell
Cell stem cell, vol 27, iss 5

Summary Non-coding mutations at the far end of a large gene desert surrounding the SOX9 gene result in a human craniofacial disorder called Pierre Robin sequence (PRS). Leveraging a human stem cell differentiation model, we identify two clusters of e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f150da7af4ebb8826bb96a6b61a3a0ca
https://www.pure.ed.ac.uk/ws/files/249582527/Loss_of_Extreme_Long_Range_Enhancers_in_Human.pdf

Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination

Autor: Nobuko Uchida, Martin R. Jakobsen, Anders Laustsen, Rosa Romano, Rasmus O. Bak, Volker Wiebking, Mara Pavel-Dinu, Toshinobu Nishimura, Hiromitsu Nakauchi, Camille Sindhu, Matthew H. Porteus, M. Kyle Cromer, Benjamin J. Lesch, Viktor T. Lemgart, Renata M. Martin, Daniel P. Dever, Andrew J. Tong, Vittorio Sebastiano, Sriram Vaidyanathan, Kazuya Ikeda, Joab Camarena

Publikováno v: Martin, R M, Ikeda, K, Cromer, M K, Uchida, N, Nishimura, T, Romano, R, Tong, A J, Lemgart, V T, Camarena, J, Pavel-Dinu, M, Sindhu, C, Wiebking, V, Vaidyanathan, S, Dever, D P, Bak, R O, Laustsen, A, Lesch, B J, Jakobsen, M R, Sebastiano, V, Nakauchi, H & Porteus, M H 2019, ' Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination ' Cell Stem Cell . https://doi.org/10.1016/j.stem.2019.04.001
Martin, R M, Ikeda, K, Cromer, M K, Uchida, N, Nishimura, T, Romano, R, Tong, A J, Lemgart, V T, Camarena, J, Pavel-Dinu, M, Sindhu, C, Wiebking, V, Vaidyanathan, S, Dever, D P, Bak, R O, Laustsen, A, Lesch, B J, Jakobsen, M R, Sebastiano, V, Nakauchi, H & Porteus, M H 2019, ' Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination ', Cell Stem Cell, vol. 24, no. 5, pp. 821-828.e5 . https://doi.org/10.1016/j.stem.2019.04.001

Summary Genome editing of human pluripotent stem cells (hPSCs) provides powerful opportunities for in vitro disease modeling, drug discovery, and personalized stem cell-based therapeutics. Currently, only small edits can be engineered with high frequ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d79cbc8377ca949930bc2fdb5c08810
https://pure.au.dk/portal/da/publications/highly-efficient-and-markerfree-genome-editing-of-human-pluripotent-stem-cells-by-crisprcas9-rnp-and-aav6-donormediated-homologous-recombination(29b31c34-5dd7-43f4-a44d-96df459cdc5c).html