Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kazuya Hirai"'
Publikováno v:
Internal medicine (Tokyo, Japan).
Publikováno v:
The Journal of toxicological sciences. 46(9)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). SARS-CoV-2 enters host cells by binding with the receptor angiotensin-converting enzyme 2 (ACE2). While ACE2 is expressed in multiple cell types,
Autor:
Tomonobu Koizumi, Kazunari Tateishi, Tsutomu Hachiya, Takashi Kobayashi, Kei Sonehara, Fumiaki Yoshiike, Yuuki Wakatsuki, Manabu Yamamoto, Takeshi Masubuchi, Kazuya Hirai, Toshirou Fukushima
Publikováno v:
Cancer Chemotherapy and Pharmacology. 81:1043-1050
This phase II study was performed to evaluate the efficacy and safety of cisplatin/pemetrexed combined with 15 mg/kg of bevacizumab followed by pemetrexed/bevacizumab maintenance therapy as first-line chemotherapy in advanced non-squamous non-small c
Autor:
Keisuke Suzuki, Masabumi Yoshino, Takuhito Nagai, Naoto Miura, Kazuya Hirai, Hirokazu Imai, Hironobu Nobata, Kanyu Miyamoto, Shogo Banno
Publikováno v:
Internal Medicine
We herein report two cases of proteinase 3-anti-neutrophil cytoplasmic antibody (PR3-ANCA)-related nephritis in infectious endocarditis. In both cases, the patients were middle-aged men with proteinuria and hematuria, hypoalbuminemia, decreased kidne
Autor:
Tomonobu Koizumi, Toshihiko Agatsuma, Fumiaki Yoshiike, Hiroshi Kuraishi, Kazunari Tateishi, Hiroki Goya, Takashi Ichiyama, Shintaro Kanda, Keishi Kubo, Hiroshi Yamamoto, Shigeru Koyama, Kazuya Hirai
Publikováno v:
Cancer Chemotherapy and Pharmacology. 70:691-697
This phase I/II study was designed to evaluate a combination of irinotecan and S-1 a new regimen for salvage chemotherapy in patients with advanced or metastatic non-small cell lung cancer (NSCLC).The study group comprised patients with advanced or m
Autor:
Tomonobu Koizumi, Masaaki Kawahara, Kazuhiro Asami, Nobutoshi Morozumi, Akio Morikawa, Shinji Atagi, Akihiro Tsukadaira, Shingo Ameshima, Kazuya Hirai
Publikováno v:
Clinical Lung Cancer. 12:387-392
Efficacy of first-line gefitinib for elderly epidermal growth factor receptor mutated patients with lung adenocarcinoma is uncertain. This study was aimed to investigate efficacy of gefitinib for such population. The primary endpoint was response rat
Autor:
Takashi Aihara, Kazuya Hirai, Shuhei Ito, Satoshi Hosoya, Susumu Ohara, Takehiko Mima, Eijiro Adachi, Hironobu Iwashiro, Shihoka Ohashi
Publikováno v:
Connective Tissue Research. 52:340-352
Dense connective tissues were generated simultaneously by accumulating collagen fibrils and fibroblasts on stainless steel mesh using a bioreactor system that we designed. The advantage of our system is that the artificial connective tissues can be g
Autor:
Natsuya Katada, Kazuya Hirai, Keishi Yamashita, Shinichi Sakuramoto, Shiro Kikuchi, Hiromitsu Moriya, Masahiko Watanabe, Nobue Futawatari
Publikováno v:
Surgical Endoscopy. 23:2416-2423
Laparoscopy-assisted total gastrectomy (LATG) is not widely used for the treatment of gastric cancer located in the upper or middle third of the stomach. To assess the safety and usefulness of LATG, we compared the outcomes of LATG with those of open
Publikováno v:
American journal of physiology. Cell physiology. 310(2)
Indoxyl sulfate (IS) is a representative uremic toxin that accumulates in the blood of patients with chronic kidney disease (CKD). In addition to the involvement in the progression of CKD, a recent report indicates that IS suppresses hypoxia-inducibl
Autor:
Hideyuki Yamato, Kazuya Hirai, Hirobumi Asai, Chiho Matsumoto, Chisato Miyaura, Masaki Inada, Mie Watanabe-Akanuma, Junya Hirata
Publikováno v:
Bone. 79
Low-turnover bone disease is one of the bone abnormalities observed in patients with chronic kidney disease (CKD) and is recognized to be associated with low serum parathyroid hormone (PTH) level and skeletal resistance to PTH. Indoxyl sulfate (IS) i