Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kazuya Nakao"'
Autor:
Kazuto Fujishima, Kazuaki Miyake, Yuta Takano, Shigeyoshi Sakaki, Kazuya Nakao, Tatsuya Murakami, Yasuo Mori, Ryuji Inoue, Wesley David Grove, Hiroshi Imahori, Tomohiro Numata, Mineko Kengaku
Publikováno v:
Chemical Science. 7:3331-3337
A series of porphyrin–fullerene linked molecules has been synthesized to evaluate the effects of substituents and molecular structures on their charge-separation yield and the lifetime of a final charge-separated state in various hydrophilic enviro
Publikováno v:
Journal of Computer-Aided Molecular Design. 23:309-319
The parallel artificial membrane permeation assay (PAMPA) was developed as a model for the prediction of transcellular permeation in the process of drug absorption. In our previous report, it was revealed that PAMPA permeability is governed by log P,
Publikováno v:
KAGAKU TO SEIBUTSU. 46:194-199
Autor:
Yuta, Takano, Tomohiro, Numata, Kazuto, Fujishima, Kazuaki, Miyake, Kazuya, Nakao, Wesley David, Grove, Ryuji, Inoue, Mineko, Kengaku, Shigeyoshi, Sakaki, Yasuo, Mori, Tatsuya, Murakami, Hiroshi, Imahori
Publikováno v:
Chemical Science
A rationally designed donor–acceptor conjugate efficiently generates a photoinduced charge-separated state in a cellular environment, achieving photoinduction of neuronal firing.
A series of porphyrin–fullerene linked molecules has been synt
A series of porphyrin–fullerene linked molecules has been synt
Publikováno v:
Optics express. 23(7)
We propose and evaluate an all-optical 2-bit header recognition and packet switching method using two 1.55-µm polarization bistable vertical-cavity surface-emitting lasers (VCSELs) and three optical switches. Polarization bistable VCSELs acted as fl
Publikováno v:
Bioorganic & Medicinal Chemistry. 13:4721-4732
To evaluate the absorption of drugs with diverse structures across a membrane via the transcellular route, their permeability was measured using the parallel artificial membrane permeation assay (PAMPA). The permeability coefficients obtained by PAMP
Autor:
Keiko Saito, Toshikazu Suzuki, Hiroshi Ohmizu, Mikiko Yasuhara, Ryo Shimizu, Hitoshi Kubota, Kazuya Nakao
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:853-861
Novel hydroxyphenylurea derivatives were synthesized and their inhibitory potency evaluated against acyl-CoA: cholesterol acyltransferase (ACAT). Quantitative structure activity relationship analysis revealed that their ACAT inhibitory activities wer
Autor:
Saburo Komatsubara, Tetsuo Ohnuki, Ryo Shimizu, Masataka Kuroda, Kazuya Nakao, Yutaka Koguchi, Jun Kohno, Maki Nishio
Publikováno v:
The Journal of Organic Chemistry. 65:990-995
Four novel proteasome inhibitors, TMC-95A-D (1-4) have been isolated from the fermentation broth of Apiospora montagnei Sacc. TC 1093, isolated from a soil sample. All of the molecular formulas of 1-4 were established as C(33)H(38)N(6)O(10) by high-r
Autor:
Masahiko Seki, Kazuya Nakao
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 63:1304-1307
Oxazoline-4-acetate derivative 3 that could be readily obtained from L-aspartic acid was subjected to highly stereoselective hydroxylation, and subsequent Mitsunobu inversion of the hydroxyl group led to (2S,3R)-3-amino-3-benzyl-2-hydroxybutanoic aci
Publikováno v:
Tetrahedron. 52:5751-5764
Stereoselective β-bromination ofN-formyl-α, β-dehydroamino acid esters 5 was investigated. A reaction of 5 with NBS affordedα-bromo-N-formylimines 10 which successively isomerized to giveβ-bromo-N-formyl-α, β-dehydroamino acid esters 4 . The m