Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kazuya Kawano"'
Autor:
Yosuke Kurashima, Takaaki Kigoshi, Sayuri Murasaki, Fujimi Arai, Kaoru Shimada, Natsumi Seki, Yun-Gi Kim, Koji Hase, Hiroshi Ohno, Kazuya Kawano, Hiroshi Ashida, Toshihiko Suzuki, Masako Morimoto, Yukari Saito, Ai Sasou, Yuki Goda, Yoshikazu Yuki, Yutaka Inagaki, Hideki Iijima, Wataru Suda, Masahira Hattori, Hiroshi Kiyono
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Glycoprotein-2 (GP-2) can protect the intestinal epithelial barrier from bacteria and is associated with protection against Crohn’s disease. Here, the authors show pancreatic GP-2 is the source of the intestine’s luminal GP-2 that binds bacteria
Externí odkaz:
https://doaj.org/article/f5da787852fa46ccab231d2284892574
Autor:
Yutaka Inagaki, Yuki Goda, Masahira Hattori, Natsumi Seki, Wataru Suda, Hideki Iijima, Yoshikazu Yuki, Toshihiko Suzuki, Yun Gi Kim, Hiroshi Ohno, Hiroshi Kiyono, Masako Morimoto, Hiroshi Ashida, Fujimi Arai, Koji Hase, Yukari Saito, Ai Sasou, Kaoru Shimada, Takaaki Kigoshi, Sayuri Murasaki, Kazuya Kawano, Yosuke Kurashima
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Increases in adhesive and invasive commensal bacteria, such as Escherichia coli, and subsequent disruption of the epithelial barrier is implicated in the pathogenesis of inflammatory bowel disease (IBD). However, the protective systems against such b
Autor:
Kinji Shirota, Takashi Kato, Ryosuke Kobayashi, Junichi Kamiie, Shoko Ishihara, Makoto Ishikawa, Rio Saito, Tomoshige Baba, Kazuya Kawano, Kyohei Yasuno, Kikumi Ogihara
Publikováno v:
Journal of Veterinary Medical Science. 72:1319-1327
Progressive glomerular injury associated with early-onset proteinuria was investigated in male Osborne-Mendel (OM) rats aged 5 to 20 weeks. Age-matched male Fischer 344 (F344) rats were used for comparison. OM rats developed mild hypertension and sel
Autor:
Hiroshi Ohno, Kazuya Kawano, Kikuji Itoh, Sayaka Kawano, Satoshi Tsuneda, Masashi Ebisawa, Yasuhiro Date, Atsushi Hijikata, Shinji Fukuda, Koji Hase
Publikováno v:
Cell Structure and Function. 32:115-126
Pregnancy-specific glycoproteins (Psgs) secreted by the placenta regulate the immune system to ensure the survival of the fetal allograft by inducing IL-10, an anti-inflammatory cytokine. However, it is unknown whether Psgs are involved in more gener
Autor:
Kikuji Itoh, Hiroyuki Takatsu, Sayaka Ohshima, Risa Chihara, Mitsutoshi Iimura, Hiroshi Ohno, Kazuya Kawano, Takeshi Shimaoka, Kimiyo Hamura, Koji Hase, Takaya Murakami, Shin Yonehara
Publikováno v:
The Journal of Immunology. 176:43-51
The recently identified CXCL16 has dual functions as a transmembrane adhesion molecule and a soluble chemokine. In this study we found that CXCL16 mRNA and protein were expressed constitutively on the follicle-associated epithelium covering Peyer’s
Autor:
Jae Ho Kim, Kazuya Kawano, Yong Jung Kang, Pann-Ghill Suh, Eun Su Jeon, Mark Donowitz, Whaseon Lee-Kwon, Jung Woong Choi, Hyeon Soo Kim
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1683:59-68
Lysophosphatidic acid (LPA) stimulates Na(+)/H(+) exchanger 3 (NHE3) activity in opossum kidney proximal tubule (OK) cells by increasing the apical membrane amount of NHE3. This occurs by stimulation of exocytic trafficking of NHE3 to the apical plas
Recovery from heat shock injury by activation of Na+-glucose cotransporter in renal epithelial cells
Autor:
Akira Ikari, Mika Nakano, Kuniaki Takagi, Yasunobu Suketa, Hitoshi Harada, Mihoko Ishibashi, Kazuya Kawano
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1643:47-53
Exposure of cells or organs to sublethal physical or chemical stresses induces disruption of cellular structures and functions. Here, we examined whether Na(+)-glucose cotransporter (SGLT1) is involved in the recovery from heat shock (HS) injury in p
Publikováno v:
Journal of Biological Chemistry. 277:33338-33343
Heat shock stress induces some heat shock proteins, including Hsp70, and activates sodium-dependent glucose transport in porcine renal LLC-PK(1) cells, but its mechanisms have not been described in detail. We investigated whether sodium-dependent glu
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 281:R222-R229
CCK-A receptors and neurons of the nucleus of the solitary tract (NTS) are involved in the regulation of food intake, and in rats, there is evidence for involvement of an intestinal vagal afferent pathway. Studies investigating the role of CCK-A rece
Publikováno v:
Metabolism. 49:108-114
With respect to the connection between triglyceride (TG) and non-insulin-dependent diabetes mellitus (NIDDM), previous reports have shown that TG accumulation in the liver and muscle is one of the causes of insulin resistance, and TG accumulation in