Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Kazuya, Ikematsu"'
Autor:
Yuki Abe, Takehiko Murase, Masahide Mitsuma, Yoriko Shinba, Hiromi Yamashita, Kazuya Ikematsu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Chronic stress has been implicated in mental illnesses and depressive behaviors. Somatostatin 4 receptor (SSTR4) has been shown to mediate anxiolytic and depression-like effects. Here, we aimed to explore the potential of SSTR4 as a diagnost
Externí odkaz:
https://doaj.org/article/337daa4ff1324c7682be7cb1c99e82f8
Autor:
Keita Shingu, Takehiko Murase, Takuma Yamamoto, Yuki Abe, Yoriko Shinba, Masahide Mitsuma, Takahiro Umehara, Hiromi Yamashita, Kazuya Ikematsu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In sudden unexpected death in infancy cases, postmortem genetic analysis with next-generation sequencing potentially can extract candidate genes associated with sudden death. However, it is difficult to accurately interpret the clinically si
Externí odkaz:
https://doaj.org/article/7c7c566a7d5e473b91676776584a8379
Autor:
Takahiro Umehara, Ryoichi Mori, Kimberly A. Mace, Katsumi Tanaka, Noriho Sakamoto, Kazuya Ikematsu, Hiroaki Sato
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3129 (2022)
Diabetes is known to delay wound healing, and this delay is attributed to prolonged inflammation. We found that microRNAs (miRNAs) might be involved in the dysfunction of diabetic-derived neutrophils, and dynamics of neutrophil and chronic inflammati
Externí odkaz:
https://doaj.org/article/e12ed60c380a495aaebf9547645b5ed3
Autor:
Motoki Osawa, Yasuhiro Ueno, Noriaki Ikeda, Kazuya Ikematsu, Takuma Yamamoto, Wataru Irie, Shuji Kozawa, Hirokazu Kotani, Hideki Hamayasu, Takehiko Murase, Keita Shingu, Marie Sugimoto, Ryoko Nagao, Yu Kakimoto
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0233253 (2020)
BackgroundSudden unexpected death in infancy (SUDI) comprises both natural and unnatural causes of death. However, few epidemiological surveys have investigated SUDI in Japan.ObjectiveThis retrospective study was conducted to investigate the latest t
Externí odkaz:
https://doaj.org/article/ba3ad9ded55d4e1aaad0d554df178737
Autor:
Maiko de Kerckhove, Katsuya Tanaka, Takahiro Umehara, Momoko Okamoto, Sotaro Kanematsu, Hiroko Hayashi, Hiroki Yano, Soushi Nishiura, Shiho Tooyama, Yutaka Matsubayashi, Toshimitsu Komatsu, Seongjoon Park, Yuka Okada, Rina Takahashi, Yayoi Kawano, Takehisa Hanawa, Keisuke Iwasaki, Tadashige Nozaki, Hidetaka Torigoe, Kazuya Ikematsu, Yutaka Suzuki, Katsumi Tanaka, Paul Martin, Isao Shimokawa, Ryoichi Mori
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 10, Pp 1-21 (2018)
Abstract Argonaute 2 bound mature microRNA (Ago2‐miRNA) complexes are key regulators of the wound inflammatory response and function in the translational processing of target mRNAs. In this study, we identified four wound inflammation‐related Ago
Externí odkaz:
https://doaj.org/article/5d5fcb93f7564cd5a95e07278a823ab0
Publikováno v:
Forensic Science International: Reports, Vol 1, Iss , Pp - (2019)
This study presents an autopsy case of unexpected sudden death caused by mitochondrial disorders with a subdural hematoma suspected to have manifested from Pearson’s marrow pancreas syndrome in a four-year-old boy. The cause of death was not determ
Externí odkaz:
https://doaj.org/article/41852a20e1344b028a4cfe21e99ae64a
Autor:
Takuma Yamamoto, Makoto Otsu, Takashi Okumura, Yumi Horie, Yasuharu Ueno, Hideki Taniguchi, Manami Ohtaka, Mahito Nakanishi, Yuki Abe, Takehiko Murase, Takahiro Umehara, Kazuya Ikematsu
Publikováno v:
Stem Cell Research, Vol 39, Iss , Pp - (2019)
We established three iPSC lines from postmortem-cultured fibroblasts derived following the sudden unexpected death of an 8-year-old girl with Lennox-Gastaut syndrome, who turned out to have the R551H-mutant STXBP1 gene. These iPSC clones showed pluri
Externí odkaz:
https://doaj.org/article/c5161fae74104a45a6719e82756dd65f
Autor:
Mohammed N. Islam, Jesmine Khan, Kazuya Ikematsu, Pramod G. Bagali, Vinoth K. Raman, Rustakiah bt M. Ali
Publikováno v:
Arab Journal of Forensic Sciences & Forensic Medicine, Vol 1, Iss 7 (2018)
Digital autopsy is the future of postmortem examination of the human body through digital visualization. Imaging modalities such as CT scanners and MRI scanners use X rays and magnetic fields to visualize the structures within the human body. The out
Externí odkaz:
https://doaj.org/article/6d36167cff054327aa338e28c824b69c
Autor:
Takuma Yamamoto, Hiroyuki Mishima, Hajime Mizukami, Yuki Fukahori, Takahiro Umehara, Takehiko Murase, Masamune Kobayashi, Shinjiro Mori, Tomonori Nagai, Tatsushige Fukunaga, Seiji Yamaguchi, Koh-ichiro Yoshiura, Kazuya Ikematsu
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 5, Iss C, Pp 26-32 (2015)
The recent introduction of metabolic autopsy in the field of forensic science has made it possible to detect hidden inherited metabolic diseases. Since the next generation sequencing (NGS) has recently become available for use in postmortem examinati
Externí odkaz:
https://doaj.org/article/f06cea9104c14fbcb7e234bf5a6a64e5
Autor:
Takahiro Umehara, Ryoichi Mori, Takehiko Murase, Toshiko Tanaka, Kentaro Kasai, Kazuya Ikematsu, Hiroaki Sato
Publikováno v:
Legal medicine (Tokyo, Japan). 59
Forensic diagnosis of fatal hypothermia is considered difficult because no specific findings, such as molecular markers, have been identified. Therefore, determining the molecular mechanism in hypothermia and identifying novel molecular markers to as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3d45861865d32774a6540170a5a951
https://pubmed.ncbi.nlm.nih.gov/36198254
https://pubmed.ncbi.nlm.nih.gov/36198254