Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Kazutoyo, Osoegawa"'
Autor:
Qin Ma, Danillo G. Augusto, Gonzalo Montero-Martin, Stacy J. Caillier, Kazutoyo Osoegawa, Bruce A. C. Cree, Stephen L. Hauser, Alessandro Didonna, Jill A. Hollenbach, Paul J. Norman, Marcelo Fernandez-Vina, Jorge R. Oksenberg
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThe HLA-DRB1 gene in the major histocompatibility complex (MHC) region in chromosome 6p21 is the strongest genetic factor identified as influencing multiple sclerosis (MS) susceptibility. DNA methylation changes associated with MS have been
Externí odkaz:
https://doaj.org/article/e17816670eb94ed78dd6ec595e2f543c
Autor:
Victoria N. Parikh, Alexander G. Ioannidis, David Jimenez-Morales, John E. Gorzynski, Hannah N. De Jong, Xiran Liu, Jonasel Roque, Victoria P. Cepeda-Espinoza, Kazutoyo Osoegawa, Chris Hughes, Shirley C. Sutton, Nathan Youlton, Ruchi Joshi, David Amar, Yosuke Tanigawa, Douglas Russo, Justin Wong, Jessie T. Lauzon, Jacob Edelson, Daniel Mas Montserrat, Yongchan Kwon, Simone Rubinacci, Olivier Delaneau, Lorenzo Cappello, Jaehee Kim, Massa J. Shoura, Archana N. Raja, Nathaniel Watson, Nathan Hammond, Elizabeth Spiteri, Kalyan C. Mallempati, Gonzalo Montero-Martín, Jeffrey Christle, Jennifer Kim, Anna Kirillova, Kinya Seo, Yong Huang, Chunli Zhao, Sonia Moreno-Grau, Steven G. Hershman, Karen P. Dalton, Jimmy Zhen, Jack Kamm, Karan D. Bhatt, Alina Isakova, Maurizio Morri, Thanmayi Ranganath, Catherine A. Blish, Angela J. Rogers, Kari Nadeau, Samuel Yang, Andra Blomkalns, Ruth O’Hara, Norma F. Neff, Christopher DeBoever, Sándor Szalma, Matthew T. Wheeler, Christian M. Gates, Kyle Farh, Gary P. Schroth, Phil Febbo, Francis deSouza, Omar E. Cornejo, Marcelo Fernandez-Vina, Amy Kistler, Julia A. Palacios, Benjamin A. Pinsky, Carlos D. Bustamante, Manuel A. Rivas, Euan A. Ashley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
There is a genetic component to the risk of severe COVID-19, but the genetic effects are difficult to separate from social constructs that covary with genetic ancestry. To address this, the authors identify determinants of COVID-19 severity using adm
Externí odkaz:
https://doaj.org/article/10002eca5587461185e42393a7dc16a5
Autor:
Kazutoyo Osoegawa, Lisa E. Creary, Gonzalo Montero-Martín, Kalyan C. Mallempati, Sridevi Gangavarapu, Stacy J. Caillier, Adam Santaniello, Noriko Isobe, Jill A. Hollenbach, Stephen L. Hauser, Jorge R. Oksenberg, Marcelo A. Fernández-Viňa
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Multiple sclerosis (MS) susceptibility shows strong genetic associations with HLA alleles and haplotypes. We genotyped 11 HLA genes in 477 non-Hispanic European MS patients and their 954 unaffected parents using a validated next-generation sequencing
Externí odkaz:
https://doaj.org/article/6f58a3c695d94969889570db0135d153
Autor:
Robert P. Milius, Kazutoyo Osoegawa, Kalyan C. Mallempati, Marcelo Fernandez-Vina, Martin Maiers, Miranda Bauer, Gonzalo Montero-Martín, Steven J. Mack
Publikováno v:
Hum Immunol
Next generation sequencing (NGS) is being applied for HLA typing in research and clinical settings. NGS HLA typing has made it feasible to sequence exons, introns and untranslated regions simultaneously, with significantly reduced labor and reagent c
Autor:
James R Priest, Kazutoyo Osoegawa, Nebil Mohammed, Vivek Nanda, Ramendra Kundu, Kathleen Schultz, Edward J Lammer, Santhosh Girirajan, Todd Scheetz, Daryl Waggott, Francois Haddad, Sushma Reddy, Daniel Bernstein, Trudy Burns, Jeffrey D Steimle, Xinan H Yang, Ivan P Moskowitz, Matthew Hurles, Richard P Lifton, Debbie Nickerson, Michael Bamshad, Evan E Eichler, Seema Mital, Val Sheffield, Thomas Quertermous, Bruce D Gelb, Michael Portman, Euan A Ashley
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005963 (2016)
Congenital heart disease (CHD) has a complex genetic etiology, and recent studies suggest that high penetrance de novo mutations may account for only a small fraction of disease. In a multi-institutional cohort surveyed by exome sequencing, combining
Externí odkaz:
https://doaj.org/article/897b1c0c4e4048629f49fa89a99239df
Autor:
Regina Spinnler, Nayera Hamdy, Ingrid Fae, Tamara Vayntrub, Katerina Tarassi, Marcelo Fernandez-Vina, Michael Halagan, Alexandra Tsirogianni, Bernd M. Spriewald, Medhat Askar, Maria Beatriz Rodriguez, Leah Zhrebker, Gideon Hönger, Gottfried Fischer, Karin Padros, Abeer Madbouly, Reem Ameen, Arthur Dunk, Shawna Kennedy, Ronald K. Charlton, Ghada I. Mossallam, Christian Bach, Salem Al Shemmari, Amanda Willis, Kazutoyo Osoegawa
Publikováno v:
Human Immunology. 80:897-905
Since their inception, the International HLA & Immunogenetics Workshops (IHIW) served as a collaborative platform for exchange of specimens, reference materials, experiences and best practices. In this report we present a subset of the results of hum
Autor:
Victoria N. Parikh, Alexander G. Ioannidis, David Jimenez-Morales, John E. Gorzynski, Hannah N. De Jong, Xiran Liu, Jonasel Roque, Victoria P. Cepeda-Espinoza, Kazutoyo Osoegawa, Chris Hughes, Shirley C. Sutton, Nathan Youlton, Ruchi Joshi, David Amar, Yosuke Tanigawa, Douglas Russo, Justin Wong, Jessie T. Lauzon, Jacob Edelson, Daniel Mas Montserrat, Yongchan Kwon, Simone Rubinacci, Olivier Delaneau, Lorenzo Cappello, Jaehee Kim, Massa J. Shoura, Archana N. Raja, Nathaniel Watson, Nathan Hammond, Elizabeth Spiteri, Kalyan C. Mallempati, Gonzalo Montero-Martín, Jeffrey Christle, Jennifer Kim, Anna Kirillova, Kinya Seo, Yong Huang, Chunli Zhao, Sonia Moreno-Grau, Steven G. Hershman, Karen P. Dalton, Jimmy Zhen, Jack Kamm, Karan D. Bhatt, Alina Isakova, Maurizio Morri, Thanmayi Ranganath, Catherine A. Blish, Angela J. Rogers, Kari Nadeau, Samuel Yang, Andra Blomkalns, Ruth O’Hara, Norma F. Neff, Christopher DeBoever, Sándor Szalma, Matthew T. Wheeler, Christian M. Gates, Kyle Farh, Gary P. Schroth, Phil Febbo, Francis deSouza, Omar E. Cornejo, Marcelo Fernandez-Vina, Amy Kistler, Julia A. Palacios, Benjamin A. Pinsky, Carlos D. Bustamante, Manuel A. Rivas, Euan A. Ashley
Publikováno v:
Nature communications, vol 13, iss 1
The SARS-CoV-2 pandemic has differentially impacted populations across race and ethnicity. A multi-omic approach represents a powerful tool to examine risk across multi-ancestry genomes. We leverage a pandemic tracking strategy in which we sequence v
Autor:
Kinya Seo, Jennifer Kim, Douglas Russo, David Jimenez-Morales, Lorenzo Cappello, Nathaniel Watson, Manuel A. Rivas, Archana Raja, Nathan Hammond, Marcelo Fernandez-Vina, Francis deSouza, Nathan Youlton, Steven G. Hershman, Kazutoyo Osoegawa, Olivier Delaneau, Shirley Sutton, Jessie T. Lauzon, Andra L. Blomkalns, Ruth O'Hara, Yongchan Kwon, Amy Kistler, Victoria N. Parikh, Yong Huang, Carlos Bustamante, Matthew T. Wheeler, Elizabeth Spiteri, Benjamin A. Pinsky, Jonasel Roque, Simone Rubinacci, Massa J. Shoura, Thanmayi Ranganath, Samuel Yang, John E. Gorzynski, Alina Isakova, Gary P. Schroth, Kyle Kai-How Farh, Yosuke Tanigawa, Ruchi Joshi, Hannah N. De Jong, Kalyan C. Mallempati, Catherine A. Blish, Christopher R. Hughes, Norma Neff, Justin Wong, Karan D. Bhatt, Sándor Szalma, Julia A. Palacios, Jimmy Zhen, Jack Kamm, Alexander G. Ioannidis, Anna Kirillova, Xiran Liu, Gonzalo Montero-Martín, Angela J. Rogers, Jeffrey W. Christle, David Amar, Maurizio Morri, Karen P. Dalton, Phil Febbo, Jaehee Kim, Victoria P. Cepeda-Espinoza, Sonia Moreno-Grau, Chunli Zhao, Christopher DeBoever, Euan A. Ashley, Kari C. Nadeau, Jacob Edelson, Daniel Mas Montserrat
The SARS-CoV-2 pandemic has differentially impacted populations of varied race, ethnicity and socioeconomic status. Admixture mapping and local ancestry inference represent powerful tools to examine genetic risk within multi-ancestry genomes independ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeee66778d9fd13a5991ed041ddf74c6
https://doi.org/10.1101/2021.08.04.21261547
https://doi.org/10.1101/2021.08.04.21261547
Autor:
Lisa E. Creary, Manuel Muro, María Francisca González-Escribano, Antonio Balas, Jose L. Vicario, Tamara Vayntrub, Maria J. Herrero-Mata, Luis Marín, Florentino Sánchez-García, Marcelo Fernandez-Vina, Javier G. Ocejo-Vinyals, Gonzalo Montero-Martín, Kazutoyo Osoegawa, Kalyan C. Mallempati, José Luis Caro-Oleas, María R. Moya-Quiles, Sridevi Gangavarapu, Dolores Planelles, Carlos Vilches, Rafael González-Fernández, F. Sánchez-Gordo
Publikováno v:
HUMAN IMMUNOLOGY
r-FISABIO. Repositorio Institucional de Producción Científica
instname
Digital.CSIC. Repositorio Institucional del CSIC
Hum Immunol
r-FISABIO. Repositorio Institucional de Producción Científica
instname
Digital.CSIC. Repositorio Institucional del CSIC
Hum Immunol
Next-generation sequencing (NGS) at the HLA-A, -B, -C, -DPA1, -DPB1, -DQA1, -DQB1, -DRB1 and -DRB3/4/5 loci was performed on 282 healthy unrelated individuals from different major regions of Spain. High-resolution HLA genotypes defined by full sequen
Autor:
Marcelo Fernandez-Vina, Stephen L. Hauser, Maneesh K. Misra, Wesley M. Marin, Jorge R. Oksenberg, Jill A. Hollenbach, Neda Nemat-Gorgani, Adam Renschen, Adam Santaniello, Lisa E. Creary, Kirsten M. Anderson, Gonzalo Montero-Martín, Vincent Damotte, Caroline M. Tanner, Kazutoyo Osoegawa, Paul Norman, Peter Parham, Ravi Dandekar, Stacy J. Caillier
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 15
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 15
Significance Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disease with both familial and sporadic forms and a clear genetic component. In addition, underlying immunoregulatory dysfunction and inflammatory processes have been