Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kazuto Hashimoto"'
Publikováno v:
Journal of Toxicologic Pathology
Extraskeletal osteosarcoma is extremely rare in humans and animals, especially in rodents. This is the first case report on spontaneous extraskeletal osteosarcoma in the neck skeletal muscle of a Crlj:CD1 (ICR) mouse (36 weeks, dead). Necropsy reveal
Autor:
Taishi Miyashita, Hiroaki Nejishima, Kazuto Hashimoto, Haruko Ogawa, Yutaka Yonezawa, Akira Kataoka, Tomoka Ohsumi
Publikováno v:
The Journal of Toxicological Sciences. 40:667-683
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Guinea pigs are the most frequently used animals in phototoxicity studies. However, general toxicity studies most often use Sprague-Dawley (SD) rats. To reduce the number of animals needed for drug development, we examined whethe
Guinea pigs are the most frequently used animals in phototoxicity studies. However, general toxicity studies most often use Sprague-Dawley (SD) rats. To reduce the number of animals needed for drug development, we examined whethe
Autor:
Hiroaki Nejishima, Yutaka Yonezawa, Kazuto Hashimoto, Hiroko Ashizawa, Taishi Miyashita, Haruko Ogawa
Publikováno v:
The Journal of toxicological sciences. 42(2)
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Previously, we showed that phototoxicity assessments in Sprague-Dawley (SD) rats can detect phototoxic potential to the same degree as those in guinea pigs. In this study, we examined whether phototoxicity assessments can be inco
Previously, we showed that phototoxicity assessments in Sprague-Dawley (SD) rats can detect phototoxic potential to the same degree as those in guinea pigs. In this study, we examined whether phototoxicity assessments can be inco
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 811
In vivo phosphatidylinositol glycan, class A (Pig-a) gene mutation assay using peripheral blood is known to be a novel and useful tool to evaluate the mutagenicity of compounds. Recently, the rat PIGRET assay which is an improved method for measuring
Autor:
Isao Karube, Kyong-Hoon Lee, Kazuto Hashimoto, Yoon-Chang Kim, Kazunori Ikebukuro, Hiroaki Suzuki
Publikováno v:
Electroanalysis. 12:1334-1338
A disposable chemical oxygen demand (COD) sensor was constructed using a microfabricated Clark-type oxygen electrode and titanium dioxide (TiO2) fine particles suspended in a sample solution. Under UV irradiation, a decrease in the dissolved oxygen i
Autor:
Kazuko Nakamasu, Yukio Kato, Mitsuhide Noshiro, Takeshi Kawamoto, Ming Shen, Kazuto Hashimoto, Yoshie Kawashima-Ohya, Osamu Gotoh
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1395:288-292
A cDNA for RGD-CAP/beta ig-h3 was cloned from a chick embryo chondrocyte cDNA library. The deduced amino acid sequence showed that the chick RGD-CAP/beta ig-h3 is 76-77% identical with human, mouse and pig forms of the protein, and 43% identical with
Autor:
Hisashi Satakeda, Haiou Pan, Tetsuji Okamoto, Yasumasa Akagawa, Weiqun Yan, Kazuhisa Nakashima, Kazuto Hashimoto, Shigeru Ohno, Yukio Kato, Hiroko Ishida, Ming Shen, Akinobu Okimura, Takeshi Kawamoto, Mitsuhide Noshiro
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (3):303-314
A 66-kDa collagen fiber-associated protein (RGD-CAP) was isolated from a fiber-rich fraction of pig cartilage by ultrafiltration and collagen-affinity chromatography. Amino acid sequencing and cDNA cloning indicated that the RGD-CAP is identical or c
Autor:
Kanata Ibi1 ibi_kanata@kaken.co.jp, Shiori Chiba1, Naomi Koyama1, Kazuto Hashimoto1, Hiroaki Nejishima1
Publikováno v:
Journal of Toxicologic Pathology. 2021, Vol. 34 Issue 2, p147-150. 4p.
Autor:
Yutaka Yonezawa1,2 yonezawa_yutaka@kaken.co.jp, Taishi Miyashita1, Hiroko Ashizawa1, Kazuto Hashimoto1, Hiroaki Nejishima1, Haruko Ogawa3
Publikováno v:
Journal of Toxicological Sciences. Apr2017, Vol. 42 Issue 2, p145-157. 13p.
Autor:
Yutaka Yonezawa1,2 yonezawa_yutaka@kaken.co.jp, Tomoka Ohsumi1, Taishi Miyashita1, Akira Kataoka1, Kazuto Hashimoto1, Hiroaki Nejishima1, Haruko Ogawa3
Publikováno v:
Journal of Toxicological Sciences. Nov2015, Vol. 40 Issue 6, p667-683. 17p.