Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kazuto, Yazawa"'
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(1):17-24
Publikováno v:
British Journal of Pharmacology. 151:1198-1203
Background and purpose: Stonefish (Synanceia genus) are commonly found in shallow waters of the Pacific and Indian Oceans. The venom of stonefish is stored in the dorsal fine spines and contains a proteinaceous toxin, verrucotoxin (VTX). The stings p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6cf167530d1cb86be4fcfab0fe2724e
https://doi.org/10.1038/sj.bjp.0707340
https://doi.org/10.1038/sj.bjp.0707340
Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway
Publikováno v:
European Journal of Pharmacology. 563:172-179
Verrucotoxin is the major component of venom from the stonefish (Synanceia verrucosa). Stings from the dorsal spines of the stonefish produce intensive pain, convulsions, hypotension, paralysis, respiratory weakness and collapse of the cardiovascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6afe7fdbd0984267831de09e6db2e4
https://doi.org/10.1016/j.ejphar.2007.02.004
https://doi.org/10.1016/j.ejphar.2007.02.004
Autor:
Kazuto Yazawa, Min Chen, Chun-Yang Xiao, Hong Ma, Akiyoshi Hara, Hiroko Hashizume, Yasushi Abiko
Publikováno v:
Cardiovascular Drug Reviews. 15:335-353
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e03a305e673a90aa8d233a0197e8a201
https://doi.org/10.1111/j.1527-3466.1997.tb00340.x
https://doi.org/10.1111/j.1527-3466.1997.tb00340.x
Publikováno v:
Japanese Journal of Pharmacology. 90:125-130
The effect of mibefradil, known as a T- and L-type Ca(2+) channel antagonist, on the histamine-induced Cl(-) current and Ca(2+) entry was investigated in human aortic endothelial cells by the fluorescence measurement of intracellular Ca(2+) concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a87690f989e2a4b85e9b5ed9cc803f2
https://doi.org/10.1254/jjp.90.125
https://doi.org/10.1254/jjp.90.125
Publikováno v:
Japanese Journal of Pharmacology. 79:17-24
We examined the effects of quinaprilat, an active metabolite of quinapril (an angiotensin converting enzyme (ACE) inhibitor) on the increase in intracellular concentration of Ca2+ ([Ca2+]i) (Ca2+-overload) induced by lysophosphatidylcholine (LPC) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3dca0f4b10ec4ccb1607e9a3bc3efd1
https://doi.org/10.1254/jjp.79.17
https://doi.org/10.1254/jjp.79.17
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 433:557-562
The role of adenosine triphosphate (ATP) in the regulation of L-type Ca2+ channel activity was investigated in inside-out patches from guinea-pig ventricular cells, in which the Ca2+ channel activity had been reprimed by application of cytoplasm from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a14931f01e035e2d9fcaab56e6ee93
https://doi.org/10.1007/s004240050314
https://doi.org/10.1007/s004240050314
Autor:
Asako Kameyama, Jianjun Xu, Masaki Kameyama, Lifeng Yu, Rui Feng, Kazuto Yazawa, Etsuko Minobe, Lei Yang
Publikováno v:
The journal of physiological sciences : JPS. 63(6)
Although Cav1.2 Ca(2+) channels are modulated by reactive oxygen species (ROS), the underlying mechanisms are not fully understood. In this study, we investigated effects of hydrogen peroxide (H2O2) on the Ca(2+) channel using a patch-clamp technique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cb44934efcc59cfa14bd6c48e0fcb9
https://pubmed.ncbi.nlm.nih.gov/23839268
https://pubmed.ncbi.nlm.nih.gov/23839268
Autor:
Kazuto Yazawa, Masaki Kameyama, Etsuko Minobe, Liying Hao, Dong-Yun Han, Xiao-yan Bai, Hadhimulya Asmara, Feng Guo
Publikováno v:
Biochemical and biophysical research communications. 391(2)
We investigated the concentration- and Ca(2+)-dependent effects of CaM mutants, CaM(12) and CaM(34), in which Ca(2+)-binding to its N- and C-lobes was eliminated, respectively, on the Ca(V)1.2 Ca(2+) channel by inside-out patch clamp in guinea-pig ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb11088e863ac7973385ce94c8caf9c
https://pubmed.ncbi.nlm.nih.gov/20006578
https://pubmed.ncbi.nlm.nih.gov/20006578
Publikováno v:
The Japanese Journal of Physiology. 40:157-163
An improved method for isolating cardiac myocytes is described. This method consists of the initial dispersion of the myocytes with a new type of collagenase and the following treatment of the cells with a non-specific protease. This method gives mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a27776b91a3b054775931073db5b4c5
https://doi.org/10.2170/jjphysiol.40.157
https://doi.org/10.2170/jjphysiol.40.157