Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Kazuto, Nosaka"'
Publikováno v:
Molecules, Vol 27, Iss 4, p 1191 (2022)
The burkholdines are a family of cyclic lipopeptides reported to exhibit antifungal activity. We synthesized a series of 18 burkholdine analogues in good yield by conventional Fmoc-SPPS followed by cyclization with DIPCI/HOBt in the solution phase. A
Externí odkaz:
https://doaj.org/article/3595df763d9a42e3bab928e4c16753ca
Publikováno v:
Chemicalpharmaceutical bulletin. 71(1)
Propan-1,3-diol (PD) and propan-1,2-diol (propylene glycol, PG) are very similar compounds because their structures, safety data, and anti-microbial activities are almost the same. Actually, both compounds are made up of three carbon atoms and two hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969209d8096fb4c3fcbd760c3ab03473
https://pubmed.ncbi.nlm.nih.gov/36596515
https://pubmed.ncbi.nlm.nih.gov/36596515
Autor:
Nobuhiro Tsuchiya, Ako Hosono, Toshiaki Yoshikawa, Kayoko Shoda, Kazuto Nosaka, Manami Shimomura, Junichi Hara, Chika Nitani, Atsushi Manabe, Hiroki Yoshihara, Yosuke Hosoya, Hide Kaneda, Yoshiaki Kinoshita, Kenichi Kohashi, Kenichi Yoshimura, Norihiro Fujinami, Keigo Saito, Shoichi Mizuno, Tetsuya Nakatsura
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
The carcinoembryonic antigen glypican-3 (GPC3) is a good target of anticancer immunotherapy against pediatric solid tumors expressing GPC3. In this non-randomized, open-label, phase I clinical trial, we analyzed the safety and efficacy of GPC3-peptid
Externí odkaz:
https://doaj.org/article/5f76819309494872a07ab5ff75f4dada
Autor:
Hiroaki Kajiyama, Kazuhisa Kitami, Manami Shimomura, Toshiaki Yoshikawa, Kazuto Nosaka, Fumitaka Kikkawa, Shiro Suzuki, Kosuke Yoshida, Tetsuya Nakatsura, Masato Yoshihara
Publikováno v:
Anticancer Research. 41:4741-4751
Background/aim Heat shock protein 105 (HSP105) is overexpressed in various cancers, but not in normal tissues. We investigated the expression levels of HSP105 in cervical cancer and the efficacy of immunotherapy targeting HSP105. Materials and method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e1991b205f31244c9e8f15b8628475
https://doi.org/10.21873/anticanres.15289
https://doi.org/10.21873/anticanres.15289
Autor:
Toshiaki Yoshikawa, Tetsuya Nakatsura, Keigo Saito, Yu Akazawa, Yuki Saito, Kazuto Nosaka, Shoichi Mizuno, Manami Shimomura, Yasunari Nakamoto
Publikováno v:
Cancer Science
Lung cancer is the leading cause of cancer-related deaths worldwide. Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) have often good clinical activity against non-small cell lung cancer (NSCLC) with activating EGFR mutations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0235abc48c3165fc62ac98627fed0f73
https://doi.org/10.1111/cas.14451
https://doi.org/10.1111/cas.14451
Autor:
Kayoko Shoda, Hideaki Bando, Takashi Kojima, Tetsuro Sasada, Itaru Endo, Satoshi Wada, Kenichi Kohashi, Kazuto Nosaka, Toshiaki Yoshikawa, Yasuhiro Shimizu, Yuki Fujimoto, Tetsuya Nakatsura, Shoichi Mizuno
Publikováno v:
Cancer Science
Heat shock protein 105 (HSP105) is overexpressed in many cancers, including colorectal cancer (CRC) and esophageal cancer (EC). We carried out a phase I clinical trial of HLA‐A24‐ and HLA‐A2‐restricted HSP105 peptide vaccines in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c4ec159f81875892fc11550e58e31b
http://europepmc.org/articles/PMC6778658
http://europepmc.org/articles/PMC6778658
Autor:
Kenichi Akaji, Kazuya Kobayashi, Ryosuke Uchiyama, Hiroyuki Konno, Kazuto Nosaka, Risako Kameda, Yasunao Hattori, Takuto Sohma
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:253-257
The plant alkaloids, iso-6-spectaline and spectaline, isolated from the Cassia or Senna genera contain a characteristic 2,6-disubstituted piperidin-3-ol scaffold. Although both natural products are reported to exhibit a variety of interesting biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38358681389ee48d0d672abacb91468c
https://doi.org/10.1248/cpb.c18-00817
https://doi.org/10.1248/cpb.c18-00817
Autor:
Shigekazu Yano, Mio Sasaki, So Chida, Kazuto Nosaka, Toma Kadowaki, Hiroyuki Konno, Seiya Kato
Publikováno v:
Tetrahedron Letters. 87:153542
The synthesis of xylose-bearing cyclic octalipopeptides burkholdine-1213 analogues is described. Sugar-containing lipopeptides are generally highly amphiphilic and often exhibit potent antifungal activities, but a synthesis of a xylose-bearing burkho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::499bed6eb3862a6c06aef2d0795998aa
https://doi.org/10.1016/j.tetlet.2021.153542
https://doi.org/10.1016/j.tetlet.2021.153542
Autor:
Risako, Kameda, Takuto, Sohma, Kazuya, Kobayashi, Ryosuke, Uchiyama, Kazuto, Nosaka, Hiroyuki, Konno, Kenichi, Akaji, Yasunao, Hattori
Publikováno v:
Chemicalpharmaceutical bulletin. 67(3)
The plant alkaloids, iso-6-spectaline and spectaline, isolated from the Cassia or Senna genera contain a characteristic 2,6-disubstituted piperidin-3-ol scaffold. Although both natural products are reported to exhibit a variety of interesting biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c780f44cdf464d785be39a73adc44e7
https://pubmed.ncbi.nlm.nih.gov/30828001
https://pubmed.ncbi.nlm.nih.gov/30828001
Autor:
Ryosuke Uchiyama, Yurina Endo, Hitomi Mimuro, Hiroyuki Konno, Maria Hayashi, Kazuto Nosaka, Kyo Tadano
Publikováno v:
Microbiology (Reading, England). 165(2)
Helicobacter pylori lacks the genes involved in the de novo synthesis of thiamin, and is therefore a thiamin auxotroph. The PnuT transporter, a member of the Pnu transporter family, mediates the uptake of thiamin across the membrane. In the genome of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f12325d32ddb9a091c4a6e2a048ba9
https://pubmed.ncbi.nlm.nih.gov/30620266
https://pubmed.ncbi.nlm.nih.gov/30620266