Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Kazutake, Shimada"'
Autor:
Tatsuya, Higashi, Kazutake, Shimada
Publikováno v:
Biomedical chromatography : BMC. 31(1)
High-performance liquid chromatography (HPLC), LC/mass spectrometry (MS) and LC/tandem mass spectrometry (MS/MS) have been widely used for biomedical analyses, in which chemical derivatization is one of the most important methods to increase the sens
Publikováno v:
Journal of Chromatography B. 878:1654-1661
The measurements of the serum/plasma concentrations of vitamin D metabolites are widely used for the diagnostic assessment and follow-up of several diseases, such as chronic renal failure and osteoporosis. These metabolites have usually been measured
Publikováno v:
Chemical and Pharmaceutical Bulletin. 57:948-956
Naturally occurring constituents of biological or pharmaceutical interest often exist in the form of glycosides or conjugates. Mass spectral investigations of these compounds require soft ionization techniques if information on molecular mass, sugar
Autor:
Tatsuya Higashi, Toshikazu Onishi, Kazutake Shimada, Yujin Shibayama, Ken ichi Kashimada, Makoto Ono, Shuki Mizutani, Kentaro Miyai
Publikováno v:
Journal of Chromatography B. 867:49-56
A sensitive liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-ESI-MS-MS) method for the quantification of 17alpha-hydroxyprogesterone (17OHP) in human saliva has been developed and validated. The saliva was deproteinized wit
Publikováno v:
Biological and Pharmaceutical Bulletin. 31:1646-1650
In this study, we examined the influence of finasteride (FIN), a 5alpha-reductase inhibitor, on the brain levels and metabolism of neurosteroids [allopregnanolone (AP), 3alpha-dihydroprogesterone (3alpha-DHP), progesterone (PROG), 20alpha-dihydroprog
Publikováno v:
Analytical and Bioanalytical Chemistry. 391:229-238
A sensitive liquid chromatography–electrospray ionization–tandem mass spectrometric (LC–ESI–MS/MS) method for the determination of 25-hydroxyvitamin D3 [25(OH)D3] in human saliva has been developed and validated. The saliva was deproteinized
Publikováno v:
Steroids. 72:865-874
The identification and quantification of tetrahydrocorticosterone isomers (THBs; 3alpha,5alpha-, 3beta,5alpha-, 3alpha,5beta- and 3beta,5beta-THB) in rat brains using liquid chromatography (LC)-mass spectrometry (MS) are described. For the identifica
Publikováno v:
Analytical Sciences. 23:1015-1019
A sensitive liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-ESI-MS/MS) method for the determination of the rat brain 5alpha-androstane-3alpha,17beta-diol (3alpha,5alpha-Adiol) has been developed and validated. The brain ex
Publikováno v:
Journal of Chromatography B. 848:188-199
A sensitive liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-ESI-MS-MS) method for the simultaneous determination of 5 alpha-reduced pregnan-type neurosteroids, allopregnanolone (AP), epiallopregnanolone and 5 alpha-dihydro
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 43:1782-1788
A simple and sensitive liquid chromatography-electrospray ionization-mass spectrometric (LC-ESI-MS) method for the simultaneous quantification of representative 17-ketosteroid sulfates, dehydroepiandrosterone sulfate (DHEAS), androsterone sulfate and