Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kazutaka Ogiwara"'
Publikováno v:
Folia Pharmacologica Japonica. 152:147-159
Nusinersen (Spinraza®) was approved as Japan's first antisense oligonucleotide (ASO) drug for treatment of SMA (spinal muscular atrophy) patients with a deletion or mutation of the survival motor neuron (SMN) 1 gene and ≥1 copy of the SMN2 gene. N
Autor:
Yogik Onky Silvana Wijaya, Kimimasa Tobita, Sakae Kumasaka, Ichiro Morioka, Akihiro Takatera, Emma Tabe Eko Niba, Atsuko Takeuchi, Yoichi Kondo, Chisako Mitsuishi, Hisahide Nishio, Isamu Hokuto, Izumi Takayama, Kazutaka Ogiwara, Masakazu Shinohara
Publikováno v:
International Journal of Neonatal Screening
Volume 5
Issue 4
Volume 5
Issue 4
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by SMN1 gene deletion/mutation. The drug nusinersen modifies SMN2 mRNA splicing, increasing the production of the full-length SMN protein. Recent studies have demonstrated the beneficia
Publikováno v:
Biochemical and Biophysical Research Communications. 345:255-259
We constructed photo-reactive epidermal growth factor (EGF) bearing p-azido phenylalanine at the C-terminal (HEGFP) by genetic engineering to investigate the possibility of immobilized EGF as a novel artificial extracellular matrix (ECM). The constru
Publikováno v:
The Journal of Japan Gnathology. 16:19-27
Publikováno v:
Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology). 36:388-398
A. actinomycetemcomitans (Aa), Pgingivalis (Pg), F. nucleotum (Fn) に対するヒト好中球の活性酸素産生 (Chemiluminescence反応: CL反応) と食菌における補体の役割, および関与する補体レセプター型について明
Autor:
Masato Nagaoka, Ezharul Hoque Chowdhury, F.T. Zohra, Koichi Kutsuzawa, Kazutaka Ogiwara, C. Kitamura, Toshihiro Akaike, Seiichi Tada
Publikováno v:
Biochemistry. 44(37)
Extracellular matrix (ECM) proteins, such as collagen and fibronectin, play vital roles in development and maintenance of hard tissue (bone or tooth) and are, consequently, thoroughly investigated for construction of biomimetic scaffolds in combinati
Publikováno v:
Biotechnology letters. 27(20)
The design of artificial extracellular matrices has attracted much attention in tissue engineering as well as in cell biology research. An immobilized recombinant epidermal growth factor (EGF), fused to an immunoglobulin G (IgG) Fc region (abbreviate