Zobrazeno 1 - 10
of 793
pro vyhledávání: '"Kazutaka IKEDA"'
Autor:
Kazutaka Ohi, Daisuke Nishizawa, Taiga Saito, Taichi Goto, Itsuki Kubota, Tomoya Shinoda, Daisuke Fujikane, Junko Hasegawa, Naomi Sato, Fumihiko Tanioka, Haruhiko Sugimura, Kazutaka Ikeda, Toshiki Shioiri
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Dietary habits may impact the prevention and management of schizophrenia (SCZ) and bipolar disorder (BD), and genetic and environmental factors can influence both these habits and these disorders. This study investigated the effects of genet
Externí odkaz:
https://doaj.org/article/552425c9e998439686617c3f7c6be924
Autor:
Ruying Zou, Daisuke Nishizawa, Rie Inoue, Junko Hasegawa, Yuko Ebata, Kyoko Nakayama, Atsuko Hara, Hiroyuki Sumikura, Mari Kitade, Masakazu Hayashida, Kazutaka Ikeda, Izumi Kawagoe
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 3, Pp 650-657 (2024)
Abstract Aim Abundant data are available on the effect of the A118G (rs1799971) single‐nucleotide polymorphism (SNP) of the μ‐opioid receptor OPRM1 gene on morphine and fentanyl requirements for pain control. However, data on the effect of this
Externí odkaz:
https://doaj.org/article/74d643f852724dc89c2c68eb503bbc72
Autor:
Yoshihiko Kosaki, Daisuke Nishizawa, Junko Hasegawa, Kaori Yoshida, Kazutaka Ikeda, Tatsuya Ichinohe
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Midazolam is widely used for intravenous sedation. However, wide interindividual variability is seen in the sensitivity to midazolam. The association between genetic factors and interindividual differences in midazolam sensitivity remains un
Externí odkaz:
https://doaj.org/article/8349feeda5734ba28d8dbb6031cb3555
Autor:
Toshio Kanno, Ryo Konno, Masaru Sato, Atsushi Kurabayashi, Keisuke Miyako, Takahiro Nakajima, Satoru Yokoyama, Shigemi Sasamoto, Hikari K. Asou, Junichiro Ohzeki, Yoshinori Hasegawa, Kazutaka Ikeda, Yusuke Kawashima, Osamu Ohara, Yusuke Endo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Recent studies have highlighted the significance of cellular metabolism in the initiation of clonal expansion and effector differentiation of T cells. Upon exposure to antigens, naïve CD4+ T cells undergo metabolic reprogramming to meet the
Externí odkaz:
https://doaj.org/article/299bfaa138b64b138aeb89989a2a7fb0
Autor:
Hirokazu Masai, Masanori Koshimizu, Hiroki Kawamoto, Hiroyuki Setoyama, Yohei Onodera, Kazutaka Ikeda, Shingo Maruyama, Naoki Haruta, Tohru Sato, Yuji Matsumoto, Chika Takahashi, Teruyasu Mizoguchi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Thermodynamically metastable glasses that can contain metastable species are important functional materials. X-ray absorption near-edge structure (XANES) spectroscopy is an effective technique for determining the valence states of cations, e
Externí odkaz:
https://doaj.org/article/acdc67a0eb224e918315ee267e7090df
Autor:
Shinsei Yambe, Yuki Yoshimoto, Kazutaka Ikeda, Koichiro Maki, Aki Takimoto, Akihide Tokuyama, Shinnosuke Higuchi, Xinyi Yu, Kenta Uchibe, Shigenori Miura, Hitomi Watanabe, Tetsushi Sakuma, Takashi Yamamoto, Kotaro Tanimoto, Gen Kondoh, Masataka Kasahara, Toshihide Mizoguchi, Denitsa Docheva, Taiji Adachi, Chisa Shukunami
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Fibrocartilaginous entheses consist of tendons, unmineralized and mineralized fibrocartilage, and subchondral bone, each exhibiting varying stiffness. Here we examined the functional role of sclerostin, expressed in mature mineralized fibrochondrocyt
Externí odkaz:
https://doaj.org/article/427052bd41564fbcaaa067f05c89e21b
Autor:
Toshiki Shioiri, Midori Soda, Kazutaka Ohi, Mihoko Shimada, Daisuke Nishizawa, Daisuke Fujikane, Kentaro Takai, Ayumi Kuramitsu, Yukimasa Muto, Shunsuke Sugiyama, Junko Hasegawa, Kiyoyuki Kitaichi, Kazutaka Ikeda
Publikováno v:
BMJ Mental Health, Vol 27, Iss 1 (2024)
Background Genetic and environmental factors contribute to the pathogenesis of schizophrenia (SZ) and bipolar disorder (BD). Among genetic risk groups stratified by combinations of Polygenic Risk Score (PRS) deciles for SZ, BD and SZ versus BD, genet
Externí odkaz:
https://doaj.org/article/6ddb017afb7b4d27a4b1935d9b6f253b
Autor:
Naotaka Izuo, Hajime Miyanishi, Daisuke Nishizawa, Takuma Fujii, Junko Hasegawa, Naomi Sato, Fumihiko Tanioka, Haruhiko Sugimura, Kazutaka Ikeda, Atsumi Nitta
Publikováno v:
Neuropsychopharmacology Reports, Vol 43, Iss 4, Pp 570-575 (2023)
Abstract Aims Cigarette smoking is a preventable risk factor for various diseases such as cancer, ischemic stroke, cardiac stroke, and chronic obstructive pulmonary disease. Smoking cessation is of great importance not only for individual smokers but
Externí odkaz:
https://doaj.org/article/56dcf0fd166b4a778b918d1fa292bc06
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Opioid addiction and the opioid overdose epidemic are becoming more serious, and the development of therapeutic agents is essential for the pharmacological treatment of substance use disorders. The κ-opioid receptor (KOP) is a member of the
Externí odkaz:
https://doaj.org/article/4f9c9cb4a3394d6bae338d3b6b6bc1f6
Autor:
Takuma Ogawa, Souichi Yamada, Shuetsu Fukushi, Yuya Imai, Jiro Kawada, Kazutaka Ikeda, Seii Ohka, Shohei Kaneda
Publikováno v:
Bioengineering, Vol 11, Iss 8, p 794 (2024)
Although methods for generating human induced pluripotent stem cell (hiPSC)-derived motor nerve organoids are well established, those for sensory nerve organoids are not. Therefore, this study investigated the feasibility of generating sensory nerve
Externí odkaz:
https://doaj.org/article/fc30343210b547b3a2efbdf179e6a035