Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Kazutaka Fukumura"'
Autor:
Cheng-Kai Shiau, Lina Lu, Rachel Kieser, Kazutaka Fukumura, Timothy Pan, Hsiao-Yun Lin, Jie Yang, Eric L. Tong, GaHyun Lee, Yuanqing Yan, Jason T. Huse, Ruli Gao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Single-cell nanopore sequencing of full-length mRNAs transforms single-cell multi-omics studies. However, challenges include high sequencing errors and dependence on short-reads and/or barcode whitelists. To address these, we develop scNanoG
Externí odkaz:
https://doaj.org/article/43beb0e6e87041e6ac17042241fa61ab
Autor:
Won-Chul Lee, Alexandre Reuben, Xin Hu, Nicholas McGranahan, Runzhe Chen, Ali Jalali, Marcelo V. Negrao, Shawna M. Hubert, Chad Tang, Chia-Chin Wu, Anthony San Lucas, Whijae Roh, Kenichi Suda, Jihye Kim, Aik-Choon Tan, David H. Peng, Wei Lu, Ximing Tang, Chi-Wan Chow, Junya Fujimoto, Carmen Behrens, Neda Kalhor, Kazutaka Fukumura, Marcus Coyle, Rebecca Thornton, Curtis Gumbs, Jun Li, Chang-Jiun Wu, Latasha Little, Emily Roarty, Xingzhi Song, J. Jack Lee, Erik P. Sulman, Ganesh Rao, Stephen Swisher, Lixia Diao, Jing Wang, John V. Heymach, Jason T. Huse, Paul Scheet, Ignacio I. Wistuba, Don L. Gibbons, P. Andrew Futreal, Jianhua Zhang, Daniel Gomez, Jianjun Zhang
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract Background Metastasis is the primary cause of cancer mortality accounting for 90% of cancer deaths. Our understanding of the molecular mechanisms driving metastasis is rudimentary. Results We perform whole exome sequencing (WES), RNA sequenc
Externí odkaz:
https://doaj.org/article/c29b76fbdc184076acd46b769c6e95c6
Autor:
Evan D. H. Gates, Jie Yang, Kazutaka Fukumura, Jonathan S. Lin, Jeffrey S. Weinberg, Sujit S. Prabhu, Lihong Long, David Fuentes, Erik P. Sulman, Jason T. Huse, Dawid Schellingerhout
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background: Treatment effectiveness and overall prognosis for glioma patients depend heavily on the genetic and epigenetic factors in each individual tumor. However, intra-tumoral genetic heterogeneity is known to exist and needs to be managed. Curre
Externí odkaz:
https://doaj.org/article/0e2fdedf54be427fab9129620dff1a0c
Autor:
Hiroyuki Mano, Tatsuya Yamasoba, Stephen D. Nimer, Kohei Miyazono, Mineo Kurokawa, Yasushi Miyazaki, Takahiro Asakage, Yoshihiro Yamashita, Eirin Sai, Manabu Soda, Azusa Yamato, Kazutaka Fukumura, Hiroyuki Yamaguchi, Takahiko Yasuda, Keisuke Kataoka, Junji Koya, Koji Ando, Daizo Koinuma, Toshihide Ueno, Masahito Kawazu, Mizuo Ando
Expression level of ELF4 in stably transduced T3M-1 Cl-10 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558a7184c8df417742e95d996a01abeb
https://doi.org/10.1158/0008-5472.22409871.v1
https://doi.org/10.1158/0008-5472.22409871.v1
Autor:
Hiroyuki Mano, Tatsuya Yamasoba, Stephen D. Nimer, Kohei Miyazono, Mineo Kurokawa, Yasushi Miyazaki, Takahiro Asakage, Yoshihiro Yamashita, Eirin Sai, Manabu Soda, Azusa Yamato, Kazutaka Fukumura, Hiroyuki Yamaguchi, Takahiko Yasuda, Keisuke Kataoka, Junji Koya, Koji Ando, Daizo Koinuma, Toshihide Ueno, Masahito Kawazu, Mizuo Ando
Caspase activities in T3M-1 Cl-10 cells infected with recombinant retroviruses for the indicated proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a82adcd78e1036c5e3bfb2ed31a9b39
https://doi.org/10.1158/0008-5472.22409844
https://doi.org/10.1158/0008-5472.22409844
Autor:
Hiroyuki Mano, Tatsuya Yamasoba, Stephen D. Nimer, Kohei Miyazono, Mineo Kurokawa, Yasushi Miyazaki, Takahiro Asakage, Yoshihiro Yamashita, Eirin Sai, Manabu Soda, Azusa Yamato, Kazutaka Fukumura, Hiroyuki Yamaguchi, Takahiko Yasuda, Keisuke Kataoka, Junji Koya, Koji Ando, Daizo Koinuma, Toshihide Ueno, Masahito Kawazu, Mizuo Ando
ELF4 (also known as MEF) is a member of the ETS family of transcription factors. An oncogenic role for ELF4 has been demonstrated in hematopoietic malignancies, but its function in epithelial tumors remains unclear. Here, we show that ELF4 can functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35217a22c53ef3ac456cc05261f8d750
https://doi.org/10.1158/0008-5472.c.6507867.v1
https://doi.org/10.1158/0008-5472.c.6507867.v1
Autor:
Cheng-Kai Shiau, Lina Lu, Rachel Kieser, Kazutaka Fukumura, Timothy Pan, Hsiao-Yun Lin, Jie Yang, Eric L. Tong, GaHyun Lee, Yuanqing Yan, Jason T. Huse, Ruli Gao
Publikováno v:
bioRxiv
Single-cell nanopore sequencing of full-length mRNAs (scNanoRNAseq) is transforming singlecell multi-omics studies. However, challenges include computational complexity and dependence on short-read curation. To address this, we developed a comprehens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602a44d33f3b704f4b99b50ef2f49460
https://europepmc.org/articles/PMC9915466/
https://europepmc.org/articles/PMC9915466/
Autor:
Cheng-Kai Shiau, Lina Lu, Rachel Kieser, Kazutaka Fukumura, Timothy Pan, Hsiao-Yun Lin, Jie Yang, Eric L. Tong, GaHyun Lee, Yuanqing Yan, Jason T. Huse, Ruli Gao
Publikováno v:
Cancer Research. 83:2069-2069
Single-cell Nanopore sequencing of full-length mRNAs is transforming single-cell multi-omics studies. However, challenges include computational complexity and dependence on short-read curation. To address this, we developed a comprehensive toolkit, s
Autor:
Bisrat G. Debeb, Jianhua Zhang, Xiaoding Hu, Grant M. Fischer, Jason T. Huse, Sharia Hernandez, Kazutaka Fukumura, Xizeng Mao, Dihua Yu, Michael A. Davies, Prit Benny Malgulwar, Xingzhi Song, Edwin R. Parra, Xiang Zhang
Publikováno v:
Acta Neuropathol
The deadly complication of brain metastasis (BM) is largely confined to a relatively narrow cross-section of systemic malignancies, suggesting a fundamental role for biological mechanisms shared across commonly brain metastatic tumor types. To identi
Autor:
Chang-Jiun Wu, Ximing Tang, David H. Peng, Marcelo V. Negrao, Aik Choon Tan, Kazutaka Fukumura, Stephen G. Swisher, John V. Heymach, Jing Wang, Xin Hu, Latasha Little, Alexandre Reuben, Jianhua Zhang, Anthony San Lucas, Kenichi Suda, Jianjun Zhang, Ali Jalali, P. Andrew Futreal, Won-Chul Lee, Shawna M Hubert, Emily Roarty, Marcus Coyle, Erik P. Sulman, Ganesh Rao, Carmen Behrens, Jason T. Huse, Rebecca Thornton, Neda Kalhor, Jihye Kim, Xingzhi Song, Don L. Gibbons, Runzhe Chen, Whijae Roh, Chia Chin Wu, Chi-Wan Chow, Daniel R. Gomez, Lixia Diao, Chad Tang, Wei Lu, Jun Li, Curtis Gumbs, Nicholas McGranahan, Junya Fujimoto, J. Jack Lee, Paul Scheet, Ignacio I. Wistuba
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-21 (2020)
Genome Biology
Genome Biology
Background Metastasis is the primary cause of cancer mortality accounting for 90% of cancer deaths. Our understanding of the molecular mechanisms driving metastasis is rudimentary. Results We perform whole exome sequencing (WES), RNA sequencing, meth