Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kazutaka Doi"'
Autor:
Guanyu Zhou, Tsutomu Shimura, Taiki Yoneima, Akiko Nagamachi, Akinori Kanai, Kazutaka Doi, Megumi Sasatani
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10213 (2024)
Age at exposure is a critical modifier of the risk of radiation-induced cancer. However, the effects of age on radiation-induced carcinogenesis remain poorly understood. In this study, we focused on tissue stem cells using Lgr5-eGFP-ires-CreERT2 mice
Externí odkaz:
https://doaj.org/article/3fafe3ebf3c94aa5bb3cdf60767aaa2c
Autor:
Keiji Suzuki, Tatsuhiko Imaoka, Masanori Tomita, Megumi Sasatani, Kazutaka Doi, Satoshi Tanaka, Michiaki Kai, Yutaka Yamada, Shizuko Kakinuma
Publikováno v:
Journal of Radiation Research. 64(2):228-249
While epidemiological data have greatly contributed to the estimation of the dose and dose-rate effectiveness factor (DDREF) for human populations, studies using animal models have made significant contributions to provide quantitative data with mech
Autor:
Keiji Suzuki, Tatsuhiko Imaoka, Masanori Tomita, Megumi Sasatani, Kazutaka Doi, Satoshi Tanaka, Michiaki Kai, Yutaka Yamada, Shizuko Kakinuma
Publikováno v:
Journal of Radiation Research. 64:210-227
While epidemiological data are available for the dose and dose-rate effectiveness factor (DDREF) for human populations, animal models have contributed significantly to providing quantitative data with mechanistic insights. The aim of the current revi
Autor:
Megumi Sasatani, Tsutomu Shimura, Kazutaka Doi, Elena Karamfilova Zaharieva, Jianxiang Li, Daisuke Iizuka, Shinpei Etoh, Yusuke Sotomaru, Kenji Kamiya
Publikováno v:
Carcinogenesis. 44:105-118
Age at exposure is a major modifier of radiation-induced carcinogenesis. We used mouse models to elucidate the mechanism underlying age-related susceptibility to radiation-induced tumorigenesis. Radiation exposure in infants was effective at inducing
Autor:
Tatsuhiko Imaoka, Mayumi Nishimura, Kazuhiro Daino, Ayaka Hosoki, Ken-ichi Kudo, Daisuke Iizuka, Kento Nagata, Masaru Takabatake, Yukiko Nishimura, Toshiaki Kokubo, Takamitsu Morioka, Kazutaka Doi, Yoshiya Shimada, Shizuko Kakinuma
Publikováno v:
Radiation Protection Dosimetry. 198:1036-1046
The uncertain cancer risk of protracted radiation exposure at low dose rates is an important issue in radiological protection. Tissue stem/progenitor cells are a supposed origin of cancer and may contribute to the dose-rate effect on carcinogenesis.
Autor:
Maruyama, Kouichi, Wang, Bing, Doi, Kazutaka, Ishibashi, Koji, Ichikawa, Sanei, Furuhata, Yoshiaki, Kubota, Masahide, Watanabe, Yoshito, Kouichi, Maruyama, Bing, Wang, Kazutaka, Doi, Yoshito, Watanabe
Publikováno v:
Journal of Radiation Research. 62(1):79-85
Since the Fukushima Dai-ichi Nuclear Power Plant (F1-NPP) accident in 2011, radiation effects on wildlife in the contaminated areas have been a major concern. The outskirts of the F1-NPP are mainly rural areas, where many rice fields and streams and
Autor:
Yoshito Watanabe, Kouichi Maruyama, San’ei Ichikawa, Masahide Kubota, Kazutaka Doi, Yoshiaki Furuhata, Bing Wang, Koji Ishibashi
Publikováno v:
Journal of Radiation Research
Since the Fukushima Dai-ichi Nuclear Power Plant (F1-NPP) accident in 2011, radiation effects on wildlife in the contaminated areas have been a major concern. The outskirts of the F1-NPP are mainly rural areas, where many rice fields, streams and res
Autor:
Doi, Kazutaka, Kai, Michiaki, Suzuki, Keiji, Imaoka, Tatsuhiko, Sasatani, Megumi, Tanaka, Satoshi, Yamada, Yutaka, Kakinuma, Shizuko, Kazutaka, Doi, Tatsuhiko, Imaoka, Yutaka, Yamada, Shizuko, Kakinuma
Publikováno v:
Radiation Research. 194(5):500-510
Uncertainties due to confounding factors in epidemiological studies have limited our knowledge of the effects of low dose-rate chronic exposure on human health. Animal experiments, wherein each subject is considered to be nearly identical, can comple
Publikováno v:
International Journal of Radiation Biology. 95:1144-1149
Purpose: The aim of this study was to establish a new method of real-time, in vivo detection of radiation damage and recovery.Methods: The thymus was observed under fluorescent light in a g...
Autor:
Maruyama, Kouichi, Iwanami , Norimasa, Takako, Maruyama-Hayakawa, Doi, Kazutaka, Wang, Bing, Kouichi, Maruyama, Kazutaka, Doi, Bing, Wang
Publikováno v:
International journal of radiation biology. 95(8):1144-1149
Purpose: The aim of this study was to establish a new method of real-time, in vivo detection of radiation damage and recovery. Methods: The thymus was observed under fluorescent light in a green fluorescent protein transgenic medaka. After irradiatio