Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Kazuta Oguri"'
Autor:
Yasushi Yamazoe, Peter I. Mackenzie, Shuso Takeda, Yuji Ito, Megumi Iwanaga, Kiyoshi Nagata, Yuji Ishii, Arief Nurrochmad, Hideyuki Yamada, Kazuta Oguri
Publikováno v:
Flinders University PURE
We have reported that the protein-protein interaction between UDP-glucuronosyltransferase (UGT) 2B7 and cytochrome P450 3A4 (CYP3A4) alters UGT2B7 function. However, the domain(s) involved in the interaction are largely unknown. To address this issue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922b2e370a977b3298c05965f0ef8133
https://doi.org/10.1124/mol.108.052001
https://doi.org/10.1124/mol.108.052001
Autor:
Yurie Kitajima, Hideyuki Yamada, Kazuta Oguri, Peter I. Mackenzie, Yoshio Nishimura, Shuso Takeda, Yuji Ishii
Publikováno v:
Flinders University PURE
Glucuronidation of morphine in humans is predominantly catalyzed by UDP-glucuronosyltransferase 2B7 (UGT2B7). Since our recent research suggested that cytochrome P450s (P450s) interact with UGT2B7 to affect its function [Takeda S et al. (2005) Mol Ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928f21337ebad06af781e2fc345d44f5
https://doi.org/10.1124/dmd.106.009738
https://doi.org/10.1124/dmd.106.009738
Publikováno v:
福岡醫學雜誌. 96(5):204-213
This review deals with the three candidate compounds which may combat with dioxins' toxicity. Geranylgeranylacetone (GGA), an antiulcer drug, counteracts suppression of body weight gain and lethality produced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d0d448865c894c80c935916c62e490ef
http://hdl.handle.net/2324/19281
http://hdl.handle.net/2324/19281
Publikováno v:
Journal of Dermatological Science Supplement. 1:S105-S112
Summary Background: Dioxins and related compounds, exemplified by 2,3,7,8-tetrachlorodibenzo-p-dioxin, are recognized as widespread, persistent and highly toxic environmental pollutants. Although numerous studies have been performed to clarify the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a02f7a9d1c782eba34b0a227e52e8b35
https://doi.org/10.1016/j.descs.2005.03.011
https://doi.org/10.1016/j.descs.2005.03.011
Publikováno v:
Biological and Pharmaceutical Bulletin. 28:1087-1090
The effect of an aryl hydrocarbon receptor (AhR) ligand on the carbonic anhydrase III (CAIII) mRNA level was studied using primary cultured hepatocytes of rats. CAIII gene which is highly suppressible by dioxins in vivo, was also suppressible in prim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547a51db81bd769df1ae2253b28a07f0
https://doi.org/10.1248/bpb.28.1087
https://doi.org/10.1248/bpb.28.1087
Publikováno v:
Journal of Health Science. 51:1-7
Abuse of drugs remains a serious and world-wide problem. As exemplified by opioids, there are large inter-individual differences in the effects and toxicity of drugs. However, the mechanism underlying such inter-individual differences remains largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc3a439ea796c2614a8b8ece9fe0824
https://doi.org/10.1248/jhs.51.1
https://doi.org/10.1248/jhs.51.1
Publikováno v:
Biological and Pharmaceutical Bulletin. 27:56-60
The effects of cytochrome P450 (P450, CYP) ligands and permeabilization of microsomes on 3-hydroxybenzo(a)pyrene [3-OH-B(a)P] glucuronidation mediated by rat hepatic microsomes were studied. While the UDP-glucuronosyltransferase (UGT) activity with n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e916322259a8c7eff86c3b6c5bade262
https://doi.org/10.1248/bpb.27.56
https://doi.org/10.1248/bpb.27.56
Publikováno v:
Drug Metabolism and Pharmacokinetics. 19:290-296
The role of selenium-binding protein (SeBP), which has a high ability to associate with acetaminophen (AAP), on the cytotoxicity of AAP was studied. To clarify this issue, we examined the cytotoxic effect of AAP using COS cells stably expressing SeBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5be39f7aacdb008feb228fd3d6cfe7
https://doi.org/10.2133/dmpk.19.290
https://doi.org/10.2133/dmpk.19.290
Autor:
Satoru Ishida, Hideyuki Yamada, Midori Yamamoto, Sanae Matsumoto, Noriko Gohyama, Kazuta Oguri, Masashi Mise, Curtis J. Omiecinski, Shoich Ito, Yasuhiro Sagara
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 18:124-130
Potential mechanisms were investigated whereby CYP2B18, a cytochrome P450 gene exhibiting high constitutive expression but only low levels of phenobarbital-inducibility in the guinea pig liver, may be differentially regulated versus the highly induci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680c197be949a31847dc053e8f551b1d
https://doi.org/10.1002/jbt.20016
https://doi.org/10.1002/jbt.20016
Autor:
Akifumi Akamine, Junpei Mutoh, Yuji Ishii, Takumi Ishida, Hideyuki Yamada, Isao Hashiguchi, Tomomi Oshimo, Kazuta Oguri, Akihisa Nishimura, Nobuyuki Koga
Publikováno v:
Biological and Pharmaceutical Bulletin. 27:1397-1402
The protective effect of geranylgeranylacetone (GGA), an antiulcer drug, against the acute toxicity and teratogenicity produced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was examined in C57BL/6J mice. When mice were co-treated, GGA reduced the lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1915a6e26d31f5fd874737bb89588078
https://doi.org/10.1248/bpb.27.1397
https://doi.org/10.1248/bpb.27.1397