Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kazushige Hamada"'
Publikováno v:
Journal of Gastroenterology. 41:151-157
It has been found that the efficacy of lamivudine (LAM) therapy can be improved by preceding administration with a short course of corticosteroid that induces a flare of the disease upon its withdrawal. Because of the side effects of corticosteroid,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c000461892b1b8689645977a9fa5d0ff
https://doi.org/10.1007/s00535-005-1734-5
https://doi.org/10.1007/s00535-005-1734-5
Publikováno v:
Hepatology. 33:1299-1302
A proportion of chronic hepatitis C patients who were treated with interferon have a sustained normalization of transaminase levels after interferon therapy without hepatitis C virus (HCV)-RNA clearance. We determined their clinical characteristics a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a186a839af3209106285be23db40a27
https://doi.org/10.1053/jhep.2001.24100
https://doi.org/10.1053/jhep.2001.24100
Autor:
Shohei Maekawa, Kazushige Hamada, Rie Tatsumi, Tetsuo Ueda, Mikiko Kobayashi, Mari Asada-Kubota, Yoshihiro Sokawa
Publikováno v:
Journal of Interferon & Cytokine Research. 18:71-74
Type I interferons (IFNs) have been used for the treatment of viral hepatitis, but it is unclear which cells in the liver are affected by injected IFN. The effects of IFN have been studied by the production of 2',5'-oligoadenylate synthetase (2'5'OAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ce4d22257b1747db3d2121cbc83e8b
https://doi.org/10.1089/jir.1998.18.71
https://doi.org/10.1089/jir.1998.18.71
Autor:
Akira Iwata, Shohei Maekawa, Shinsuke Kawai, Yoshinori Koh, Yoshihiro Sokawa, Kazushige Hamada, Souji Murayama, Susumu Ueda, Akira Yamamoto
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1395:181-191
We have isolated two types of chicken 2',5'-oligoadenylate synthetase cDNAs, A and B, which encode predicted proteins of 508 amino acids (58316 Da) and 476 amino acids (54336 Da), respectively. The region of A-protein comprising 33 amino acid residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ebb9db6e6884cbdd328bc36acdff44
https://doi.org/10.1016/s0167-4781(97)00148-6
https://doi.org/10.1016/s0167-4781(97)00148-6
Publikováno v:
Gene. 166:233-236
We have confirmed that the DNA replication-related element (DRE) consisting of an 8-bp palindrome, TATCGATA, and not neighboring sequences, are responsible for activating promoters of the Drosophila melanogaster (Dm) PCNA (proliferating cell nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e49e21084fe69810d2c376c906038e0
https://doi.org/10.1016/0378-1119(95)00586-2
https://doi.org/10.1016/0378-1119(95)00586-2
Autor:
Tomoaki Nakajima, Kazushige Hamada, Teruhisa Morikawa, Yuichi Harano, Tadao Okuno, Michiko Shindo
Publikováno v:
Hepatology research : the official journal of the Japan Society of Hepatology. 38(12)
Aim: 2′,5′ oligoadenylate synthetase (2-5AS), an enzyme induced by interferon, is an accurate indicator of the antiviral effect of interferon. We measured it during pegylated interferon based therapies in patients with chronic hepatitis C virus (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0978d5035c81ca7e64ee2c219761e5b1
https://pubmed.ncbi.nlm.nih.gov/18713278
https://pubmed.ncbi.nlm.nih.gov/18713278
Autor:
Christina M. Sax, James R. Flanagan, Joram Piatigorsky, Tomoyuki Nakamura, Heiner Westphal, Kazushige Hamada, B Norman, David M. Donovan, Keiko Ozato
Publikováno v:
Molecular and Cellular Biology. 10:3700-3708
We have shown by site-directed mutagenesis that the sequence between positions -69 and -40 of the mouse alpha A-crystallin gene is crucial for tissue-specific gene expression in a transfected mouse lens epithelial cell line transformed with the early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9db3cf7572d26135f5180bb4a17786bf
https://doi.org/10.1128/mcb.10.7.3700
https://doi.org/10.1128/mcb.10.7.3700
Publikováno v:
Journal of gastroenterology. 39(3)
To determine the best indicator of the effective use of interferon and lamivudine for the treatment of hepatitis B e antigen-positive chronic hepatitis, we retrospectively analyzed histologic and virologic status in 200 patients who were treated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf6c7ab72c706af1a2ae17b5ab99dbb
https://pubmed.ncbi.nlm.nih.gov/15065004
https://pubmed.ncbi.nlm.nih.gov/15065004
Publikováno v:
Liver. 22(2)
Approximately 10% of chronic hepatitis C patients who were treated with interferon have a sustained normalization of aminotransferase levels after interferon therapy without HCV RNA clearance. We investigated genetic change in hypervariable region 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aaad8d79725abd896dfb5adecb0e2ad4
https://pubmed.ncbi.nlm.nih.gov/12028415
https://pubmed.ncbi.nlm.nih.gov/12028415
Publikováno v:
Gene. 271(2)
The 2′,5′-oligoadenylate synthetase (2-5OAS) is a enzyme that catalyzes synthesis of 2′,5′-oligoadenylates (2-5A) in a dsRNA-dependent manner, and known as a major component of the IFN-induced host defense mechanisms against microbial infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4d4be177166c7de629155cdf902807
https://pubmed.ncbi.nlm.nih.gov/11418248
https://pubmed.ncbi.nlm.nih.gov/11418248