Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kazushi Shigemasa"'
Autor:
Nobutaka Nagai, Lijun Gu, Timothy J. O'Brien, Hong Hua Jin, Koso Ohama, Yoshiki Kudo, Mayu Yunokawa, Hirotoshi Tanimoto, Kazushi Shigemasa
Publikováno v:
Tumor Biology. 27:274-282
To clarify the biological behavior of TADG-14/KLK8, we investigated TADG-14/KLK8 mRNA by semiquantitative RT-PCR and hK8 expression by immunohistochemistry using 37 normal endometria and 44 endometrial carcinoma tissues. TADG-14/KLK8 mRNA expression
Autor:
Xiurong Tian, Takashi Sawasaki, Kazushi Shigemasa, Timothy J. O'Brien, Lijun Gu, Hirotoshi Tanimoto, John B. Beard
Publikováno v:
British Journal of Cancer
Tumour-associated differentially expressed gene-15 (TADG-15/ST14/matriptase/MT-SP1) is a novel member of the transmembrane serine proteases. Previous studies indicated that TADG-15 is overexpressed in ovarian tumours; however, relationships between e
Publikováno v:
Clinical Cancer Research. 10:2766-2770
Purpose: The purpose of this study was to examine expression levels of the human tissue kallikrein 11 gene (KLK11) in epithelial ovarian tumors and to identify the relationship between KLK11 expression and patient survival. Experimental Design: KLK11
Autor:
K.O. Lloyd, O. Nilsson, H.W.A. de Bruijn, Kari Hauge Olsen, B. Jansson, Timothy J. O'Brien, Kazushi Shigemasa, Yuri Lebedin, K. Nustad
Publikováno v:
Tumor Biology. 23:303-314
CA 125 is found in body fluids in a variety of molecular weight forms. The largest species are found in normal abdominal fluid and cervical mucus. The present study therefore incorporated CA 125 deriv
Autor:
Keiji Mukai, Koso Ohama, Osamu Katoh, Shoji Mihara, Kazushi Shigemasa, Yuko Shiroyama, Nobutaka Nagai
Publikováno v:
Japanese Journal of Cancer Research : Gann
To investigate the potential role of the BCL-2 gene family (BAX, BCL-2, MCL-1, and BCL-XL) in ovarian cancer development and progression, mRNA expression levels of these genes were measured using semi-quantitative PCR in epithelial ovarian tumor tiss
Autor:
Toshihiro Uesaka, Yasuo Takimoto, Hiromitsu Watanabe, Ken Kuramoto, Akiro Kimura, Kenji Oda, Osamu Katoh, Akira Sakai, Kazushi Shigemasa, Takako Tsujimoto, Hideki Asaoku
Publikováno v:
British Journal of Haematology. 116:158-161
Summary. We evaluated the level of MCL1 gene expression using quantitative reverse transcription polymerase chain reaction in lymph nodes of patients with non-Hodgkin lymphoma (NHL). MCL1 expression in patients in complete remission (CR) was signific
Publikováno v:
Obstetrics & Gynecology. 98:680-684
OBJECTIVE: To estimate the probability of and risk factors for the recurrence of invasive cervical carcinoma over 5 years after initial therapy. METHODS: Patients (n = 827) with invasive cervical carcinoma were treated and received follow-up care for
Autor:
Tomoyo Kusuda, Yuko Shiroyama, Tim H. Parmley, Timothy J. O'Brien, Kazushi Shigemasa, Takashi Sawasaki, Tsuneo Fujii, Koso Ohama
Publikováno v:
Journal of the Society for Gynecologic Investigation. 8:179-185
We investigated the relationship between cyclin E mRNA overexpression and p53 protein accumulation in epithelial ovarian cancers. mRNA was isolated and cDNA was prepared from 36 epithelial ovarian tumors (three adenomas, three low malignant potential
Autor:
Yinxiang Wang, Lowell J. Underwood, Hirotoshi Tanimoto, Timothy J. O'Brien, Tim H. Parmley, Kazushi Shigemasa
Publikováno v:
Tumor Biology. 22:104-114
Proteases have been implicated in the extracellular modulation required for tumor growth and invasion. In an effort to categorize those proteases contributing to ovarian carcinoma progression, we have utilized redundant primers to conserved amino aci
Autor:
Timothy J. O'Brien, Kazushi Shigemasa, Lowell J. Underwood, Hirotoshi Tanimoto, Tim H. Parmley, Koso Ohama, John B. Beard
Publikováno v:
Journal of the Society for Gynecologic Investigation. 7:358-362
Objective:In a continued effort to identify and characterized secreted proteases that are overexpressed in ovarian carcinomas, we discovered the testisin protease as such a candidate. When this dis...