Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Kazushi Imai"'
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69777 (2013)
The binding of p120-catenin and β-catenin to the cytoplasmic domain of E-cadherin establishes epithelial cell-cell adhesion. Reduction and loss of catenin expression degrades E-cadherin-mediated carcinoma cell-cell adhesion and causes carcinomas to
Externí odkaz:
https://doaj.org/article/9d95ddbd4fc448019a1718fcfe851804
Autor:
Takashi Hashimoto, Yuichi Soeno, Genta Maeda, Yuji Taya, Takaaki Aoba, Masanori Nasu, Shuichi Kawashiri, Kazushi Imai
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47899 (2012)
The cadherin switch from E-cadherin to N-cadherin is considered as a hallmark of the epithelial-mesenchymal transition and progression of carcinomas. Although it enhances aggressive behaviors of adenocarcinoma cells, the significance and role of cadh
Externí odkaz:
https://doaj.org/article/157384b87b8c40d69f37bf20d290034d
Supplementary Figures 1-3, Tables 1-2 from Epigenetic Loss of Mucosa-Associated Lymphoid Tissue 1 Expression in Patients with Oral Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db206fb39bbc31875d9e562ebfb9efb
https://doi.org/10.1158/0008-5472.22377620
https://doi.org/10.1158/0008-5472.22377620
Autor:
Noritaka Yamazaki, Haruka Sudo, Yuji Taya, Yuuichi Soeno, Hideo Matsumoto, Yasunori Okada, Kazushi Imai
Increased vascularity in the synovium of patients with rheumatoid arthritis (RA) is thought to result from angiogenesis. However, other possibilities to develop vasculatures by mechanism(s) like vasculogenic mimicry remain elusive. In this study, exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::588317cf4b4c55207daa9c985386249c
https://doi.org/10.21203/rs.3.rs-2127147/v1
https://doi.org/10.21203/rs.3.rs-2127147/v1
Autor:
Kazushi Imai, Nozomi Mihara-Tomiyama, Yuki Kodama, Kiran Chada, Masaru Igarashi, Yoshiaki Ide, Devipriya Harinath, Noriko Tominaga, Jeanine D'Armiento, Taka Nakahara, Munehiro Maeda
Publikováno v:
Biochemical and Biophysical Research Communications. 509:1008-1014
Tooth formation is accomplished under strict genetic programs. Although patients with chromosome 12q14 aberration shows tooth phenotype including the size and eruption timing with bone growth anomaly, its etiology is uncertain. Here, we examined expr
Publikováno v:
Biochemical and biophysical research communications. 542
Loss of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) expression closely associates with increased aggressive behaviors of oral carcinoma cells. It emphasizes that a mechanism to suppress the expression is an important su
Publikováno v:
Biochemical and biophysical research communications. 508(2)
An increase in the vasculature is one of most representative changes in the synovial tissue of joints in rheumatoid arthritis (RA) and is closely associated with disease progression. Although the vasculatures are believed to be a result of VE-cadheri
Autor:
Yuji Taya, Shuichi Kawashiri, Kazushi Imai, Yasunori Okada, Haruka Sudo, Hisao Yagishita, Yuichi Soeno, Tadashige Chiba, Youichi Shirako
Publikováno v:
Journal of Dental Research. 95:446-452
The expression of mucosa-associated lymphoid tissue 1 (MALT1) that activates nuclear factor (NF)–κB in lymphocyte lineages is rapidly inactivated in oral carcinoma cells at the invasive front and the patients with worst prognosis. However, its mec
Autor:
Yuji Taya, Tadashige Chiba, Yoshihito Shimazu, Kaori Sato, Takaaki Aoba, Kazushi Imai, Youichi Shirako, Yuuichi Soeno
Publikováno v:
Journal of Oral Pathology & Medicine. 44:656-668
Background Oral squamous cell carcinoma exhibits a poor prognosis, caused by aggressive progression and early-stage metastasis to cervical lymph nodes. Here, we developed a xenograft mouse model to explore the heterogeneity of the tumor microenvironm
Autor:
Hisao Yagishita, Yoshito Ohyama, Hideaki Sakashita, Kazushi Imai, Tadashige Chiba, Yukihiro Kawamoto
Publikováno v:
International Journal of Oncology. 43:729-736
Progression of oral carcinomas associates with aberrant activation and inactivation of molecules that work in established or unknown pathways. Although mucosa‑associated lymphoid tissue 1 (MALT1) expressed in normal oral epithelium is inactivated i