Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Kazuro, Ikawa"'
Autor:
Shiro Beppu, Takuro Nishikawa, Dan Tomomasa, Atsushi Hijikata, Hiroshi Kasabata, Hideyuki Terazono, Kazuro Ikawa, Tatsuro Nakamura, Shogo Horikawa, Jun Nagahama, Aki Nakamura, Takanari Abematsu, Shunsuke Nakagawa, Kaoru Oketani, Hirokazu Kanegane, Yasuhiro Okamoto
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundNewborn screening (NBS) for severe combined immunodeficiency (SCID) has improved the prognosis of SCID. In Japan, NBS testing (measurement of the T-cell receptor excision circles (TREC) and kappa-deleting recombination excision circles (KRE
Externí odkaz:
https://doaj.org/article/3b2f6d45857942f99c846397a9129779
Autor:
Takuro Nishikawa, Emiko Miyahara, Ieharu Yamazaki, Kazuro Ikawa, Shunsuke Nakagawa, Yuichi Kodama, Yoshifumi Kawano, Yasuhiro Okamoto
Publikováno v:
Diseases, Vol 12, Iss 5, p 85 (2024)
The pathogenesis of cyclophosphamide (CY)-induced cardiotoxicity remains unknown, and methods for its prevention have not been established. To elucidate the acute structural changes that take place in myocardial cells and the pathways leading to myoc
Externí odkaz:
https://doaj.org/article/b336b9aa697f456f93e25672498f1198
Autor:
Erika Watanabe, Kazuaki Matsumoto, Kazuro Ikawa, Yuta Yokoyama, Akari Shigemi, Yuki Enoki, Yasuhiro Umezaki, Koyo Nakamura, Keiichiro Ueno, Hideyuki Terazono, Norifumi Morikawa, Yasuo Takeda
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 24, Iss , Pp 83-87 (2021)
Objectives: Pharmacokinetic/pharmacodynamic (PK/PD) analysis using murine infection models is a well-established methodology for optimising antimicrobial therapy. Therefore, we investigated the PK/PD indices of teicoplanin againstStaphylococcus aureu
Externí odkaz:
https://doaj.org/article/074a031110824a18ab1ea363f3b857a3
Autor:
Tetsushu Onita, Kazuro Ikawa, Noriyuki Ishihara, Hiroki Tamaki, Takahisa Yano, Kohji Naora, Norifumi Morikawa
Publikováno v:
Antibiotics, Vol 12, Iss 2, p 303 (2023)
This study aimed to assess the dosing regimens of ampicillin/sulbactam for pneumonia based on pulmonary pharmacokinetic (PK)/pharmacodynamic (PD) target attainment. Using the literature data, we developed pulmonary PK models and estimated the probabi
Externí odkaz:
https://doaj.org/article/0d79a52d3dbd4783b3b902d59a8418b7
Autor:
Yasuhiro Umezaki, Kazuaki Matsumoto, Kazuro Ikawa, Yuta Yokoyama, Yuki Enoki, Akari Shigemi, Erika Watanabe, Koyo Nakamura, Keiichiro Ueno, Hideyuki Terazono, Norifumi Morikawa, Yasuo Takeda
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 982 (2022)
The bacterium Pseudomonas aeruginosa is known to be associated with nosocomial infections around the world. Pazufloxacin, a potent DNA gyrase inhibitor, is known to be an effective drug candidate. However, it has not been clarified whether the pharma
Externí odkaz:
https://doaj.org/article/e687c3b1dc6a46fab35f201068aa9fb1
Autor:
Kosuke Yoshimura, Hiroki Ohge, Kazuro Ikawa, Shinnosuke Uegami, Yusuke Watadani, Norifumi Shigemoto, Toshinori Hirano, Hiroki Kitagawa, Yuki Kaiki, Norifumi Morikawa, Shinya Takahashi
Publikováno v:
Infectious Diseases and Therapy. 12:193-207
Recently, complicated intra-abdominal infections (cIAI) have been caused not only by Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, and Pseudomonas aeruginosa, but also by extended-spectrum β-lactamase-producing Enterobacterales memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b569b1b91a75977a348de91598986f
https://doi.org/10.1007/s40121-022-00720-x
https://doi.org/10.1007/s40121-022-00720-x
Pharmacodynamic Evaluation of Ampicillin-sulbactam in Pediatric Patients Using Plasma and Urine Data
Autor:
Tetsushu Onita, Kazuro Ikawa, Noriyuki Ishihara, Hiroki Tamaki, Takahisa Yano, Kohji Naora, Norifumi Morikawa
Publikováno v:
Pediatric Infectious Disease Journal. 41:411-416
We aimed to develop population pharmacokinetic (PK) models of ampicillin and sulbactam using pooled data analysis and to optimize dosing regimens of ampicillin-sulbactam (combination ratio of 2:1) in pediatric patients.Population PK models of ampicil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7d9db2025023f19a121a023ca117ba
https://doi.org/10.1097/inf.0000000000003496
https://doi.org/10.1097/inf.0000000000003496
Autor:
Noriyuki Ishihara, Nobuhiro Nishimura, Kazuro Ikawa, Fumi Karino, Kiyotaka Miura, Hiroki Tamaki, Takahisa Yano, Takeshi Isobe, Norifumi Morikawa, Kohji Naora
Publikováno v:
Antibiotics, Vol 9, Iss 3, p 113 (2020)
The aim of this study was to develop a population pharmacokinetic model for piperacillin (PIPC)/tazobactam (TAZ) in late elderly patients with pneumonia and to optimize the administration planning by applying pharmacokinetic/pharmacodynamic (PK/PD) c
Externí odkaz:
https://doaj.org/article/474fde183f65439c94434d4bcc2f6ad8
Autor:
Yuki Kaiki, Hiroki Ohge, Kazuro Ikawa, Shinnosuke Uegami, Yusuke Watadani, Norifumi Shigemoto, Toshinori Hirano, Kosuke Yoshimura, Hiroki Kitagawa, Norifumi Morikawa, Shinya Takahashi
Publikováno v:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
Cefmetazole (CMZ) has gained interest as a carbapenem-sparing alternative to the epidemic of extended-spectrum β-lactamase (ESBL)-producing Enterobacterales (ESBL-E). In this study, we investigated the pharmacokinetics (PK) of CMZ in plasma, periton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ec66b9a539cfc97997464b68b91f3d
https://pubmed.ncbi.nlm.nih.gov/36549644
https://pubmed.ncbi.nlm.nih.gov/36549644
Autor:
Toshinori Hirano, Hiroki Ohge, Kazuro Ikawa, Shinnosuke Uegami, Yusuke Watadani, Norifumi Shigemoto, Kosuke Yoshimura, Hiroki Kitagawa, Yuki Kaiki, Norifumi Morikawa, Shinya Takahashi
Publikováno v:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
Flomoxef is generally used to treat abdominal infections and as antibiotic prophylaxis during lower gastrointestinal surgery. It is reportedly effective against extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae and an increasingly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8196fdd42af1d60e9bd1fc5f5577a9
https://pubmed.ncbi.nlm.nih.gov/36341996
https://pubmed.ncbi.nlm.nih.gov/36341996