Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kazuomi Nakamura"'
Autor:
Kaoru Kobayashi, Tsuneo Deguchi, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Shoko Takehara, Kazuomi Nakamura, Atsushi Kurihara, Mitsuo Oshimura, Yasuhiro Kazuki
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract UDP‐glucuronosyltransferases (UGTs) catalyze the conjugation of various substrates with sugars. Since the UGT2 family forms a large cluster spanning 1.5 Mb, transgenic mouse lines carrying the entire human UGT2 family have not been constru
Externí odkaz:
https://doaj.org/article/8792878571ce483887e7d51d35ed617c
Autor:
Takashi Baba, Dai Miyazaki, Kodai Inata, Ryu Uotani, Hitomi Miyake, Shin-ichi Sasaki, Yumiko Shimizu, Yoshitsugu Inoue, Kazuomi Nakamura
Publikováno v:
eLife, Vol 9 (2020)
Age-associated sterile inflammation can cause dysregulated choroidal neovascularization (CNV) as age-related macular degeneration (AMD). Intraocular fluid screening of 234 AMD patients identified high levels of IL-4. The purpose of this study was to
Externí odkaz:
https://doaj.org/article/6e247087dff2431eb8dd28e7d1056dcb
Autor:
Kumi Morikawa, Kazuomi Nakamura, Yoshiko Suyama, Kenshiro Yamamoto, Kohei Fukuoka, Shunjiro Yagi, Yasuaki Shirayoshi, Tetsuya Ohbayashi, Ichiro Hisatome
Publikováno v:
Biochemistry and Biophysics Reports, Vol 18, Iss , Pp - (2019)
In the present study, we have established a novel transgenic mouse and transgenic rats with dual reporters of EGFP and ELuc. In these transgenic (Tg) rodents, both GFP fluorescent and luciferase luminescent signals were ubiquitously detected in the h
Externí odkaz:
https://doaj.org/article/8962e8e7fe674a9bb106a4fd4356505a
Autor:
Yasuhiro Watanabe, Yasuhiro Kazuki, Kanako Kazuki, Mitsutaka Ebiki, Mami Nakanishi, Kazuomi Nakamura, Miho Yoshida Yamakawa, Hiroyuki Hosokawa, Tetsuya Ohbayashi, Mitsuo Oshimura, Kenji Nakashima
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
A human artificial chromosome (HAC) is maintained as an episome within a cell and avoids random integration into the host genome. It can transfer multiple and/or large transgenes along with their regulatory elements thereby resembling native chromoso
Externí odkaz:
https://doaj.org/article/7b3cad4755e34e48bf6e1eb705d7d900
Autor:
Yuki Yoshimura, Kazuomi Nakamura, Misako Seno, Misa Mochizuki, Kenji Kawai, Satoshi Koba, Tatsuo Watanabe
Publikováno v:
Experimental Animals. 72:95-102
Autor:
Misako Seno, Hermawan Wibisono, Tasuku Harada, Yuki Yoshimura, Kazuomi Nakamura, Kayoko Morimoto, Fuminori Taniguchi
Publikováno v:
Experimental Animals. 71:184-192
The pathogenesis of endometriosis has not been fully elucidated. We focused on the behavior of the ectopic endometrium, that is, the origin of the endometriotic lesion, before adhering to the peritoneal cavity. To observe lesion formation in the very
Autor:
Kaoru Kobayashi, Tsuneo Deguchi, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Shoko Takehara, Kazuomi Nakamura, Atsushi Kurihara, Mitsuo Oshimura, Yasuhiro Kazuki
Publikováno v:
Pharmacology Research & Perspectives. 10
UDP-glucuronosyltransferases (UGTs) catalyze the conjugation of various substrates with sugars. Since the UGT2 family forms a large cluster spanning 1.5 Mb, transgenic mouse lines carrying the entire human UGT2 family have not been constructed becaus
Autor:
Yuki, Yoshimura, Kazuomi, Nakamura, Misako, Seno, Misa, Mochizuki, Kenji, Kawai, Satoshi, Koba, Tatsuo, Watanabe
Publikováno v:
Experimental animals.
c-Fos is a useful marker gene of neuron activation for neuroscience and physiology research. The mechanism and function of neural networks have been elucidated using c-Fos reporter knock-in (KI) mice, but the small size of the mice makes it difficult
Autor:
Tomoaki Takata, Shintaro Hamada, Yukari Mae, Takuji Iyama, Ryohei Ogihara, Misako Seno, Kazuomi Nakamura, Miki Takata, Takaaki Sugihara, Hajime Isomoto
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9410
Uromodulin, a urinary protein synthesized and secreted from the thick ascending limb (TAL) of the loop of Henle, is associated with hypertension through the activation of sodium reabsorption in the TAL. Uromodulin is a potential target for hypertensi
Autor:
Kazuomi Nakamura, Yoshitsugu Inoue, Ryu Uotani, Hitomi Miyake, Shin-ichi Sasaki, Dai Miyazaki, Kodai Inata, Takashi Baba, Yumiko Shimizu
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Age-associated sterile inflammation can cause dysregulated choroidal neovascularization (CNV) as age-related macular degeneration (AMD). Intraocular fluid screening of 234 AMD patients identified high levels of IL-4. The purpose of this study was to