Zobrazeno 1 - 10
of 399
pro vyhledávání: '"Kazuo OKAMOTO"'
Autor:
Nam Cong-Nhat Huynh, Rui Ling, Masatsugu Komagamine, Tianshu Shi, Masayuki Tsukasaki, Kotaro Matsuda, Kazuo Okamoto, Tatsuo Asano, Ryunosuke Muro, Warunee Pluemsakunthai, George Kollias, Yuko Kaneko, Tsutomu Takeuchi, Sakae Tanaka, Noriko Komatsu, Hiroshi Takayanagi
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-18 (2024)
Abstract Background Recent single-cell RNA sequencing (scRNA-seq) analysis revealed the functional heterogeneity and pathogenic cell subsets in immune cells, synovial fibroblasts and bone cells in rheumatoid arthritis (RA). JAK inhibitors which ameli
Externí odkaz:
https://doaj.org/article/ea3736b484c44dd68e91bd945e1b9dbe
Autor:
Yutaro Ando, Masayuki Tsukasaki, Nam Cong-Nhat Huynh, Shizao Zang, Minglu Yan, Ryunosuke Muro, Kazutaka Nakamura, Masatsugu Komagamine, Noriko Komatsu, Kazuo Okamoto, Kenta Nakano, Tadashi Okamura, Akira Yamaguchi, Kazuyuki Ishihara, Hiroshi Takayanagi
Publikováno v:
International Journal of Oral Science, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract The immune-stromal cell interactions play a key role in health and diseases. In periodontitis, the most prevalent infectious disease in humans, immune cells accumulate in the oral mucosa and promote bone destruction by inducing receptor acti
Externí odkaz:
https://doaj.org/article/ef68d310d1a64d4c82fa538d60156728
Autor:
Masatsugu Komagamine, Noriko Komatsu, Rui Ling, Kazuo Okamoto, Shi Tianshu, Kotaro Matsuda, Tsutomu Takeuchi, Yuko Kaneko, Hiroshi Takayanagi
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-14 (2023)
Abstract Background The types of bone damage in rheumatoid arthritis (RA) include joint erosion, periarticular osteoporosis, and systemic osteoporosis. Janus kinase (JAK) inhibitors ameliorate inflammation and joint erosion in RA, but their effect on
Externí odkaz:
https://doaj.org/article/d2dde201594e419d8b474911715267a4
Autor:
Minglu Yan, Masayuki Tsukasaki, Ryunosuke Muro, Yutaro Ando, Kazutaka Nakamura, Noriko Komatsu, Takeshi Nitta, Tadashi Okamura, Kazuo Okamoto, Hiroshi Takayanagi
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract The bony skeleton is continuously renewed throughout adult life by the bone remodeling process, in which old or damaged bone is removed by osteoclasts via largely unknown mechanisms. Osteocytes regulate bone remodeling by producing the osteo
Externí odkaz:
https://doaj.org/article/a84accbec20048e48a0b1505927f768f
Autor:
Takehito Ono, Ryosuke Denda, Yuta Tsukahara, Takashi Nakamura, Kazuo Okamoto, Hiroshi Takayanagi, Tomoki Nakashima
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Impaired locomotion has been extensively studied worldwide because those afflicted with it have a potential risk of becoming bedridden. Physical exercise at times can be an effective remedy for frailty, but exercise therapy cannot be applied
Externí odkaz:
https://doaj.org/article/6a423d0218e3443181205c2da744d03b
Autor:
Masayuki Tsukasaki, Noriko Komatsu, Takako Negishi-Koga, Nam Cong-Nhat Huynh, Ryunosuke Muro, Yutaro Ando, Yuka Seki, Asuka Terashima, Warunee Pluemsakunthai, Takeshi Nitta, Takashi Nakamura, Tomoki Nakashima, Shinsuke Ohba, Haruhiko Akiyama, Kazuo Okamoto, Roland Baron, Hiroshi Takayanagi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Intramembranous and endochondral bone formation have been considered to be independent processes mediated by independent stem cells. Here the authors show that periosteal stem cells participate in both types of bone formation, supporting endochondral
Externí odkaz:
https://doaj.org/article/84b0cf37270643d4a190d9226bc66f24
Publikováno v:
Symmetry, Vol 14, Iss 8, p 1620 (2022)
Diluters play a crucial role for reducing the rotational viscosity of liquid crystal (LC) materials for improving the response property of LC displays (LCDs). However, conventional diluters tend to deteriorate relatively easily under ultraviolet (UV)
Externí odkaz:
https://doaj.org/article/8d64d03eefc34a84aeb86e4ad7fe0d5a
Autor:
Masayuki Tsukasaki, Noriko Komatsu, Kazuki Nagashima, Takeshi Nitta, Warunee Pluemsakunthai, Chisa Shukunami, Yoichiro Iwakura, Tomoki Nakashima, Kazuo Okamoto, Hiroshi Takayanagi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
IL-17-producing T cells are protective against infection, but the authors of this article previously showed that these cells also contribute to inflammatory bone destruction. Here they show in the context of periodontitis that microbiota-driven Th17-
Externí odkaz:
https://doaj.org/article/89c1ce4662c546e1b7232d546be96290
Autor:
Takehito Ono, Kazuo Okamoto, Tomoki Nakashima, Takeshi Nitta, Shohei Hori, Yoichiro Iwakura, Hiroshi Takayanagi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
γδ T cells are innate-like lymphocytes that regulate immune responses by producing IL-17A or IFN-γ, but have no known role in bone healing. Here the authors show a nonimmune bone-regenerative function of IL-17A produced by the Vγ6+ subset in mice
Externí odkaz:
https://doaj.org/article/679616e474a54998a71bde011fcf764b
Autor:
Yousuke Ohyama, Kazuo Okamoto
Publikováno v:
Annales de la Faculté des sciences de Toulouse : Mathématiques. 29:1053-1062
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87a6a352207f9f05d45a300b38ff013d
https://doi.org/10.5802/afst.1656
https://doi.org/10.5802/afst.1656