Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kazuo Nakahama"'
Autor:
Shigenori Ohkawa, Takeshi Sakane, Osamu Uchikawa, Mitsuru Kawada, Yoichi Nagano, Naoki Tarui, Kiyoharu Matsumoto, Kazuo Nakahama
Publikováno v:
Journal of Bioscience and Bioengineering. 93:44-47
The chiral indan derivative (S)-2 (2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl-amine) was synthesized by enzyme-catalyzed asymmetric hydrolysis of the racemic acetamide 1 (N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddd428ec30181ca0421895217e0e968
https://doi.org/10.1016/s1389-1723(02)80052-4
https://doi.org/10.1016/s1389-1723(02)80052-4
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:865-870
Microbial conversion of deuterium-labelled TAK-637 ((aR,9S)-[10,10,11, 11-2H4]-7-[3,5-bis(trifluoromethyl)benzyl]-8,9,10,11-tetrahydro-9-methyl-5-(4-methylphenyl)-7H-[1,4]diazocino[2,1-g][1,7]naphthyridine-6,13-dione, 1) was carried out using Strepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4f40be7e726c77fa431ddae8cc1a0f
https://doi.org/10.1002/jlcr.513
https://doi.org/10.1002/jlcr.513
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 66:464-466
Racemic indan derivatives have been resolved by the hydrolysis of amide bonds using Corynebacterium ammoniagenes IFO12612 to produce (S)-amine and (R)-amides. In the kinetic resolution of 1 (N-[2-(6-methoxy-indan-1-yl)ethyl]acetamide), it was possibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b10a7d9c75ea4b56bba67fdde1a3895
https://doi.org/10.1271/bbb.66.464
https://doi.org/10.1271/bbb.66.464
Autor:
Toru Yamano, Yumiko Nishiguchi, Isao Aoki, Shinji Tokuyama, Kazuo Nakahama, Kunio Takanohashi
Publikováno v:
Bulletin of the Chemical Society of Japan. 66:1456-1460
The enzyme-catalyzed kinetic resolution of (±)-(3aα,4α,6aα)-4-acetoxy-1,3-dibenzyl-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one [(RS)-(3a)] was examined. Lipase B from Pseudomonas fragi and rabbit liver esterase gave (−)-[3aR-(3aα,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70a38735f4ca5be960af8ca73a9bcf6c
https://doi.org/10.1246/bcsj.66.1456
https://doi.org/10.1246/bcsj.66.1456
Publikováno v:
Chemistry Letters. 22:741-744
An efficient optical resolution of (±)-(3aα,4α,6aα)-1,3-dibenzyl-3a,4,6,6a-tetrahydro-4-hydroxy-1H-thieno[3,4-d]imidazol-2(3H)-one [(RS)-1] was accomplished by acylation with lipoprotein lipase from Pseudomonas aeruginosa TE3285 in toluene. The l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0054cf344fa4a4464bc0a3d5ad020926
https://doi.org/10.1246/cl.1993.741
https://doi.org/10.1246/cl.1993.741
Publikováno v:
Journal of Bioscience and Bioengineering. 92:285-287
The compound TAK-637 ((aR,9R)-7-[3,5-bis(trifluoromethyl)benzyl]-8,9,10,11-tetrahydro-9-methyl-5-(4-methylphenyl)-7H-[1,4]diazocino[2,1-g][1,7]naphthyridine-6,13-dione), a tachykinin receptor antagonist, has been shown to be converted into three meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c1f323b50caa5f5d26cbb9e0375b33
https://doi.org/10.1016/s1389-1723(01)80263-2
https://doi.org/10.1016/s1389-1723(01)80263-2
Autor:
Shinji Tokuyama, Toru Yamano, Kazuo Nakahama, Isao Aoki, Yumiko Nishiguchi, Kunio Takanohashi
Publikováno v:
ChemInform. 24
The enzyme-catalyzed kinetic resolution of (±)-(3aα,4α,6aα)-4-acetoxy-1,3-dibenzyl-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one [(RS)-(3a)] was examined. Lipase B from Pseudomonas fragi and rabbit liver esterase gave (−)-[3aR-(3aα,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff5850dab0e966809d13ec9d6342697
https://doi.org/10.1002/chin.199339297
https://doi.org/10.1002/chin.199339297
Autor:
Hidefumi Yukimasa, Masakuni Kori, Kazuo Nakahama, Kiyoharu Matsumoto, Yoichi Nagano, Toshiaki Nagata, Motowo Izawa, Takashi Miki, Naoki Tarui
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2ed4eb1863055bbf076508caa266353
https://doi.org/10.1002/chin.200229174
https://doi.org/10.1002/chin.200229174
Autor:
Atsushi Kakinuma, Koji Yoshimura, Shizue Nakagawa, Yoshihiko Kaisho, Kenji Kawahara, Yumiko Kitamura, Reiko Sasada, Asae Shintani, Makoto Iwane, Kazuo Nakahama
Publikováno v:
Biochemical and Biophysical Research Communications. 171:116-122
The human NGF gene was isolated and inserted downstream from murine leukemia virus LTR in a plasmid having dihydrofolate reductase cDNA. The expression plasmid was introduced into CHO cells. Selection of the transformants for the resistance to methot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d026f637d0c088b3b6ae6039ba214cf3
https://doi.org/10.1016/0006-291x(90)91364-x
https://doi.org/10.1016/0006-291x(90)91364-x
Autor:
Hidefumi Yukimasa, Takashi Miki, Masakuni Kori, Kazuo Nakahama, Motowo Izawa, Naoki Tarui, Yoichi Nagano, Toshiaki Nagata, Kiyoharu Matsumoto
Publikováno v:
Chemicalpharmaceutical bulletin. 50(1)
Microbial enantioselective ester hydrolysis for the preparation of optically active (3R,5S)-(-)-5-phenyl-4,1-benzoxazepine-3-acetic acid derivatives as potent squalene synthase inhibitors was investigated. Pseudomonas diminuta and Pseudomonas taetrol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3b21dde1b19f6c19c59daa9303de2f
https://pubmed.ncbi.nlm.nih.gov/11824586
https://pubmed.ncbi.nlm.nih.gov/11824586