Zobrazeno 1 - 10
of 435
pro vyhledávání: '"Kazuo Achiwa"'
Publikováno v:
Synthetic Communications. 35:857-865
Racemic trans‐2,3‐di[(3,4‐methylenedioxy)benzyl]‐1,4‐butanediol (dihydrocubebin) 6 was enantioselectively esterified using lipases as catalysts with vinyl acetate. Optically active (S,S)‐1,4‐butanediol 6 obtained was selectively oxygena
Publikováno v:
Chemical and Pharmaceutical Bulletin. 52:1445-1450
Axially chiral biphenyldiphosphine ligands bearing diphenylphosphino group(s) and/or dicyclohexylphosphino group(s) were prepared in enantiomerically pure form starting from 2,6-dimethylnitrobenzene via 8 steps: iodination, reduction, methoxylation t
Publikováno v:
Tetrahedron Letters. 41:499-502
A biocatalytic dediastereomerization method, i.e. reactions allowing the transformation of two diastereomers into one diastereomer in quantitative yield, has been developed.
Publikováno v:
Chemical and Pharmaceutical Bulletin. 48:32-40
For the determination of favorable binding linkages of lipid A analog as a synthetic immunoadjuvant to the antigen moiety for synthetic vaccines, new N-acylated L-serine-containing D-glucosamine analogs (Type A, B, C) were synthesized and their mitog
Autor:
Kazuo Achiwa, Masumi Takemoto
Publikováno v:
Tetrahedron Letters. 40:6595-6598
A new method has been developed for the synthesis of styrenes through the decarboxylation of trans-cinnamic acids by plant cell cultures at room temperature. 4-Hydroxy-3-methoxystyrene (2a), 3-nitrostyrene (2d) and furan (2e) were synthesized quantit
Publikováno v:
Chemical and Pharmaceutical Bulletin. 47:529-535
We have synthesized a series of novel 1-isoindolinone derivatives, which inhibited the contraction of pig coronary artery induced by U-46619, a thromboxane A2 analog.
Autor:
Kazuo Achiwa, Tatsuhisa Kato
Publikováno v:
Current Organic Chemistry. 3:77-106
Since thalidomide shock, it has been recognized that the enantiomers of chiral medicines have the different pharmacological activities, and many chemists have tried to synthesize such medicines in an optically pure form. But most of them were develop
Publikováno v:
Chemical and Pharmaceutical Bulletin. 47:436-439
Novel chiral bisphosphine ligands bearing (2S, 5S)-dimethylphospholano group on a chiral biphenyl back-bone were designed and prepared. Asymmetric hydrogenations of a ketone and an olefin with the rhodium(I) complex catalysts prepared in situ from [R
Publikováno v:
Carbohydrate Research. 312:183-189
5,9-Diacetamido-2,6-anhydro- O -4-carbamoylmethyl-3,5,9-trideoxy- d - glycero - d - galacto -non-2-enonic acid ( 1 ) was synthesized via a key intermediate 2 through the Neu5Ac aldolase [E.C.4.1.3.3]-catalyzed aldol reaction of 2-acetamido-2,6-dideox
Publikováno v:
Tetrahedron: Asymmetry. 9:741-744
Enantioselective allylic substitutions using ketene silyl acetals 3 as a nucleophile have been explored. In the asymmetric reactions of 1,3-diphenylprop-2-enyl pivalate 2 catalyzed by the Pd(0)–chiral amidine 1 complex, excellent levels of stereoco