Zobrazeno 1 - 10
of 277
pro vyhledávání: '"Kazuo, Sugamura"'
Autor:
Akira Nakazato, Mai Mochizuki, Rie Shibuya-Takahashi, Haruna Fujimori, Keitaro Fujii, Satoshi Saijoh, Shinkichi Morita, Tomoko Yamazaki, Takayuki Imai, Ikuro Sato, Kennichi Satoh, Kazunori Yamaguchi, Kazuo Sugamura, Jun Yasuda, Kazuto Matsuura, Hideo Shojaku, Yukinori Asada, Keiichi Tamai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract CD271 (also referred to as nerve growth factor receptor or p75NTR) is expressed on cancer stem cells in hypopharyngeal cancer (HPC) and regulates cell proliferation. Because elevated expression of CD271 increases cancer malignancy and correl
Externí odkaz:
https://doaj.org/article/4d23e5b687c8404ca589bd25e53422a8
Autor:
Keiichi Tamai, Mao Nakamura-Shima, Rie Shibuya-Takahashi, Shin-Ichiro Kanno, Akira Yasui, Mai Mochizuki, Wataru Iwai, Yuta Wakui, Makoto Abue, Kuniharu Yamamoto, Koh Miura, Masamichi Mizuma, Michiaki Unno, Sadafumi Kawamura, Ikuro Sato, Jun Yasuda, Kazunori Yamaguchi, Kazuo Sugamura, Kennichi Satoh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract Cancer stem cells (CSCs) define a subpopulation of cancer cells that are resistant to therapy. However, little is known of how CSC characteristics are regulated. We previously showed that dormant cancer stem cells are enriched with a CD274lo
Externí odkaz:
https://doaj.org/article/46f507a261a544359c2ee01e6ca995c1
Autor:
Keitaro Fujii, Shinkichi Morita, Mai Mochizuki, Rie Shibuya‐Takahashi, Haruna Fujimori, Kazunori Yamaguchi, Jiro Abe, Tomoko Yamazaki, Takayuki Imai, Kazuo Sugamura, Jun Yasuda, Kennichi Satoh, Ikuro Sato, Ryoko Saito‐Koyama, Fumiyoshi Fujishima, Hironobu Sasano, Yukinari Kato, Kazuto Matsuura, Yukinori Asada, Keiichi Tamai
Publikováno v:
Cancer Science. 113:2878-2887
Various proteins are highly expressed in cancer (e.g., epidermal growth factor receptor); however, the majority are also expressed in normal cells, although they may differ in expression intensity. Recently, we reported that CD271 (nerve growth facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55db741bbdf4920db2993b9064b24528
https://doi.org/10.1111/cas.15340
https://doi.org/10.1111/cas.15340
Autor:
Yu Katayose, Jun Yasuda, Kazunori Yamaguchi, Daisuke Fukushi, Keiichi Tamai, Mai Mochizuki, Kazuhiro Murakami, Yuta Wakui, Kennichi Satoh, Kazuo Sugamura, Takayuki Kogure, Chikashi Shibata, Makoto Abue, Haruna Fujimori, Rie Shibuya-Takahashi, Yasuhiro Nakamura, Wataru Iwai, Takahiro Sugai
Publikováno v:
Cancer Science
Cancer stem cells (CSCs) are responsible for therapy resistance and share several properties with normal stem cells. Here, we show that brain‐expressed X‐linked gene 2 (BEX2), which is essential for dormant CSCs in cholangiocarcinoma, is highly e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c43d19dd6dd3fe198755826decd1879
http://europepmc.org/articles/PMC8586677
http://europepmc.org/articles/PMC8586677
Autor:
Mai Mochizuki, Sadafumi Kawamura, Kazuto Matsuura, Keiichi Tamai, Takayuki Imai, Wataru Iwai, Jun Yasuda, Akira Sugawara, Yukinori Asada, Makoto Abue, Tomoko Yamazaki, Haruna Fujimori, Rie Shibuya-Takahashi, Satoshi Saijoh, Ryo Ito, Yukio Katori, Mao Nakamura-Shima, Kazuo Sugamura, Kazunori Yamaguchi, Yu Katayose, Yuta Wakui, Kennichi Satoh
Publikováno v:
Biochemical and Biophysical Research Communications. 537:132-139
Cancer stem cells (CSCs) are believed to cause cancer metastasis and recurrence. BEX2 (brain expressed X-linked gene 2) is a CSC-related gene that is expressed in dormant CSCs in cholangiocarcinoma and induces resistance against chemotherapy. The aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e561f94e494a4d80cb47574f7039444
https://doi.org/10.1016/j.bbrc.2020.11.022
https://doi.org/10.1016/j.bbrc.2020.11.022
Autor:
Kazunori Yamaguchi, Wataru Iwai, Michiaki Unno, Kazuo Sugamura, Keiichi Tamai, Yuta Wakui, Makoto Abue, Tomoka Takanashi, Yuuri Hatsuzawa, Jun Yasuda, Ikuro Sato, Mai Mochizuki, Masamichi Mizuma, Kuniharu Yamamoto
Publikováno v:
Pancreatology. 20:493-500
Background Accumulating evidence indicates that CD109, a glycosylphosphatidylinositol-anchored glycoprotein, is highly expressed in human epithelial carcinomas of multiple organs including the pancreas, but its functional role in carcinoma developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ce095718734e1bdce27c2d0024a281
https://doi.org/10.1016/j.pan.2020.01.013
https://doi.org/10.1016/j.pan.2020.01.013
Autor:
Jun Yasuda, Sadafumi Kawamura, Shinkichi Morita, Kazunori Yamaguchi, Mai Mochizuki, Kennichi Satoh, Keiichi Tamai, Kazuo Sugamura, Yukinori Asada, Yukio Katori, Mao Nakamura-Shima, Tomoko Yamazaki, Kazuto Matsuura, Takayuki Imai, Rie Shibuya-Takahashi
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 39:6-11
CD271 is a common receptor for all neurotrophins that is localized to neurons, endothelial cells, and the basal layer of the epithelium in normal tissue. Recently, we and others reported that CD271 plays essential roles in the development of squamous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff31f59874640d81916e89fbcfe16627
https://doi.org/10.1089/mab.2019.0040
https://doi.org/10.1089/mab.2019.0040
Autor:
Kazunori Yamaguchi, Takayuki Imai, Mai Mochizuki, Mao Nakamura, Ikuro Sato, Kennichi Satoh, Satomi Takahashi, Tomoyuki Yokose, Tomoko Yamazaki, Yohei Miyagi, Rie Sibuya, Toshimasa Okazaki, Keiichi Tamai, Jiro Abe, Atsushi Takano, Hiroyuki Ito, Yataro Daigo, Takayuki Nakagawa, Kazuo Sugamura
Publikováno v:
Laboratory Investigation. 99:1349-1362
Squamous cell carcinoma is a major type of cancer in the lung. While several therapeutic target molecules for lung adenocarcinoma have been identified, little is known about lung squamous cell carcinoma (LSCC). We recently reported that CD271 (p75 ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76d606098e366d75d8b85e0c15b1e846
https://doi.org/10.1038/s41374-019-0246-5
https://doi.org/10.1038/s41374-019-0246-5
Autor:
Takayuki Imai, Keiichi Tamai, Sayuri Oizumi, Kyoko Oyama, Kazunori Yamaguchi, Ikuro Sato, Kennichi Satoh, Kazuto Matsuura, Shigeru Saijo, Kazuo Sugamura, Nobuyuki Tanaka
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62002 (2013)
Cancer stem cells contribute to the malignant phenotypes of a variety of cancers, but markers to identify human hypopharyngeal cancer (HPC) stem cells remain poorly understood. Here, we report that the CD271(+) population sorted from xenotransplanted
Externí odkaz:
https://doaj.org/article/c77e94ee6931454bbe14da98b8252b9c
Autor:
Hiroyuki Endo, Takeharu Shiroki, Takayuki Nakagawa, Misa Yokoyama, Keiichi Tamai, Hideaki Yamanami, Tsuneaki Fujiya, Ikuro Sato, Kazunori Yamaguchi, Nobuyuki Tanaka, Katsunori Iijima, Tooru Shimosegawa, Kazuo Sugamura, Kennichi Satoh
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77070 (2013)
The long non-coding RNA HOTAIR has been reported to be a poor prognostic biomarker in a variety of malignant tumors. However, little is known about the association of HOTAIR with gastric cancer. We examined the expression of HOTAIR in 68 gastric canc
Externí odkaz:
https://doaj.org/article/56393c871a7c4375bd80c9fed5411dab