Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kazunori Yoshikiyo"'
Autor:
Takafumi Yotsumoto, Naomi Morozumi, Mayumi Furuya, Toshihito Fujii, Keisho Hirota, Yohei Ueda, Kazumasa Nakao, Shigeki Yamanaka, Kazunori Yoshikiyo, Sayaka Yoshida, Tomonari Nishimura, Yasuyuki Abe, Toshimasa Jindo, Hiroyuki Ogasawara, Akihiro Yasoda
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216340 (2019)
C-type natriuretic peptide (CNP)-knockout (KO) rats exhibit impaired skeletal growth, with long bones shorter than those in wild-type (WT) rats. This study compared craniofacial morphology in the CNP-KO rat with that in the Spontaneous Dwarf Rat (SDR
Externí odkaz:
https://doaj.org/article/a87c07389d0e46a7af89d30fa445a359
Autor:
Naomi Morozumi, Takafumi Yotsumoto, Akira Yamaki, Kazunori Yoshikiyo, Sayaka Yoshida, Ryuichi Nakamura, Toshimasa Jindo, Mayumi Furuya, Hiroaki Maeda, Yoshiharu Minamitake, Kenji Kangawa
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212680 (2019)
C-type natriuretic peptide (CNP) and its receptor natriuretic peptide receptor B (NPR-B) are physiological potent positive regulators of endochondral bone growth; therefore, the CNP/NPR-B signaling pathway is one of the most promising therapeutic tar
Externí odkaz:
https://doaj.org/article/a23874efccb247c8b70edd59fc1c6e1e
Autor:
Keisho Hirota, Mayumi Furuya, Naomi Morozumi, Kazunori Yoshikiyo, Takafumi Yotsumoto, Toshimasa Jindo, Ryuichi Nakamura, Koichiro Murakami, Yohei Ueda, Takeshi Hanada, Hiroko Sade, Sayaka Yoshida, Kei Enomoto, Yugo Kanai, Ichiro Yamauchi, Takafumi Yamashita, Yoriko Ueda-Sakane, Toshihito Fujii, Akihiro Yasoda, Nobuya Inagaki
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204172 (2018)
Signaling by C-type natriuretic peptide (CNP) and its receptor, natriuretic peptide receptor-B, is a pivotal stimulator of endochondral bone growth. We recently developed CNP knockout (KO) rats that exhibit impaired skeletal growth with early growth
Externí odkaz:
https://doaj.org/article/542e5c9eb917416c890d01ccb0e2e6b7
ASB20123: A novel C-type natriuretic peptide derivative for treatment of growth failure and dwarfism
Autor:
Hiroaki Maeda, Takafumi Yotsumoto, Mayumi Furuya, Kenji Kangawa, Sayaka Yoshida, Akira Yamaki, Toshimasa Jindo, Kazunori Yoshikiyo, Naomi Morozumi, Yoshiharu Minamitake, Ryuichi Nakamura
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212680 (2019)
PLoS ONE
PLoS ONE
C-type natriuretic peptide (CNP) and its receptor natriuretic peptide receptor B (NPR-B) are physiological potent positive regulators of endochondral bone growth; therefore, the CNP/NPR-B signaling pathway is one of the most promising therapeutic tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f63811ea749e941bc93bda915fd6559
https://doaj.org/article/a23874efccb247c8b70edd59fc1c6e1e
https://doaj.org/article/a23874efccb247c8b70edd59fc1c6e1e
Publikováno v:
Human molecular genetics. 28(1)
Cardio-facio-cutaneous (CFC) syndrome, a genetic disorder caused by germline mutations in BRAF, KRAS, MAP2K1 and MAP2K2, is characterized by growth retardation, heart defects, dysmorphic facial appearance and dermatologic abnormalities. We have previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681d3ae6da8686eda1139ff496934b81
https://pubmed.ncbi.nlm.nih.gov/30239744
https://pubmed.ncbi.nlm.nih.gov/30239744
Autor:
Lara G. Phillips, Kouji Hirota, Toshiki Tsurimoto, Takeo Narita, Kazunori Yoshikiyo, Alan R. Lehmann, Shunichi Takeda, Julian E. Sale, Kana Nishihara, Junko Murai, Kaori Kobayashi, Kouich Yamada, Yves Pommier, Masataka Tsuda, Jun Nakamura, Guillaume Guilbaud
Publikováno v:
Nucleic Acids Research
The replicative DNA polymerase Polδ consists of a catalytic subunit POLD1/p125 and three regulatory subunits POLD2/p50, POLD3/p66 and POLD4/p12. The ortholog of POLD3 in Saccharomyces cerevisiae, Pol32, is required for a significant proportion of sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae4371ec9dfcef82c8609074ea44c6c
https://doi.org/10.1093/nar/gkv023
https://doi.org/10.1093/nar/gkv023
Autor:
Goh Murayama, Yoshinari Takasaki, Mie Kitagaichi, Ken Yamaji, Naoto Tamura, Sachiko Miyake, Kazunori Yoshikiyo, Asako Chiba
Publikováno v:
Arthritis Research & Therapy
Background Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes constituting a large proportion of peripheral blood T cells expressing αβ T-cell receptor in humans. In this study, we aimed to investigate their involvement in syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a33f4667ba83392f334de864ac543de
https://doi.org/10.1186/s13075-017-1257-5
https://doi.org/10.1186/s13075-017-1257-5
Autor:
Hiroshi Wakao, Kazunori Yoshikiyo, Kei Enomoto, Hiroyoshi Fujita, Hisanori Minakami, Manami Ohtaka, Tomoko Furukawa, Mahito Nakanishi, Yusuke Yasutomi, Nobuyuki Harada, Rika Wakao, Olivier Lantz, Jyunji Tanaka, Ken Nishimura, Uichi Koshimizu, Kazue Higuchi, Tomoyuki Sasaki, Atsushi Oda, Tomofumi Tanaka, Takashi Yamada, Yukie Sekiya, Tadashi Udagawa, Tomomi Matsunaga
Publikováno v:
Cell Stem Cell. 12(5):546-558
SummaryMucosal-associated invariant T (MAIT) cells play an important physiological role in host pathogen defense and may also be involved in inflammatory disorders and multiple sclerosis. The rarity and inefficient expansion of these cells have hampe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0a0f383eeaf3d182ed47eefd16d62d
Autor:
Yuichi Mazaki, Uichi Koshimizu, Toshiyuki Fukazawa, Chie Sugimoto, Hidenao Sasaki, Makoto Hirotani, Hiroshi Wakao, Kazunori Yoshikiyo, Takahiro Horinouchi, Rika Wakao, Hiroyoshi Fujita, Tsunehiko Higashi
Publikováno v:
SpringerPlus
Background Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory demyelination, gliosis and axonal loss in the Central Nervous System. Although the etiology of the disease has remained enigmatic, recent studies have suggested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020de600b6349c1e6a7356db3f5c1e91
http://europepmc.org/articles/PMC4974206
http://europepmc.org/articles/PMC4974206
Autor:
Sayaka Yoshida, Kei Enomoto, Toshimasa Jindo, Keisho Hirota, Yohei Ueda, Koichiro Murakami, Hiroko Sade, Takeshi Hanada, Akihiro Yasoda, Yugo Kanai, Yoriko Ueda-Sakane, Naomi Morozumi, Kazunori Yoshikiyo, Nobuya Inagaki, Ryuichi Nakamura, Ichiro Yamauchi, Takafumi Yamashita, Toshihito Fujii, Takafumi Yotsumoto, Mayumi Furuya
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0204172 (2018)
PLoS ONE, Vol 13, Iss 9, p e0204172 (2018)
Signaling by C-type natriuretic peptide (CNP) and its receptor, natriuretic peptide receptor-B, is a pivotal stimulator of endochondral bone growth. We recently developed CNP knockout (KO) rats that exhibit impaired skeletal growth with early growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232ecc809b1585a2ef4361195a87ca16
https://doi.org/10.1371/journal.pone.0204172
https://doi.org/10.1371/journal.pone.0204172