Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Kazunori Maebashi"'
Autor:
Yoko Hirai, Ko Kumura, Keiko Yamada, Kazunori Maebashi, Yoshinari Wakiyama, Eijiro Umemura, Keiichi Ajito
Publikováno v:
The Journal of antibiotics. 74(2)
Methicillin-resistant Staphylococcus aureus (MRSA) is one of causative bacteria for hospital- and community-acquired infections. In order to overcome MRSA infection, we synthesized compound A, a lincomycin derivative, and evaluated the biological pro
Autor:
Shoichi Murakami, Yoshihisa Akiyama, Hideki Fushimi, Yoko Hirai, Yukiko Hiraiwa, Kazunori Maebashi, Daishiro Ikeda, Takayuki Usui, Nobuto Minowa
Publikováno v:
The Journal of Antibiotics. 71:363-371
To overcome serious methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa infections, we synthesized TS2037, 5,4″-diepi-arbekacin, a novel aminoglycoside antibiotic, and evaluated its biological properties. TS2037 showed bro
Autor:
Mari Maeda, Mohamed Mahdi Alshahni, Yuji Tabata, Kazunori Maebashi, Shigeru Abe, Sho Takahata, Kubota Natsuki, Tsuyoshi Yamada, Naomi Takei-Masuda
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:873-880
Despite the existing treatment options for onychomycosis, there remains a strong demand for potent topical medications. ME1111 is a novel antifungal agent that is active against dermatophytes, has an excellent ability to penetrate human nails, and is
Autor:
Sho Takahata, Naomi Takei-Masuda, Makoto Ohyama, Yuji Tabata, Maiko Iida, Kazunori Maebashi, Kubota Natsuki, Kaori Kaneda
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:1035-1039
Fungal nail infection (onychomycosis) is a prevalent disease in many areas of the world, with a high incidence approaching 23%. Available antifungals to treat the disease suffer from a number of disadvantages, necessitating the discovery of new effic
Autor:
Kaori Kaneda, Yuji Tabata, Naomi Takei-Masuda, Sho Takahata, Yu Nagira, Xiaoying Hui, Masahiro Nomoto, Natsuki Kubota-Ishida, Howard I. Maibach, Tsubasa Chikada, Kazunori Maebashi
Publikováno v:
Antimicrobial agents and chemotherapy, vol 62, iss 1
ME1111 is a novel antifungal agent currently under clinical development as a topical onychomycosis treatment. A major challenge in the application of topical onychomycotics is penetration and dissemination of antifungal agent into the infected nail p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9606d621f3ccbe3379f8bba134472b2
https://europepmc.org/articles/PMC5740379/
https://europepmc.org/articles/PMC5740379/
Autor:
David M. Livermore, Takashi Ida, Akihiro Morinaka, Kazunori Maebashi, Russell Hope, Shazad Mushtaq
Publikováno v:
Journal of Antimicrobial Chemotherapy. 68:153-158
Objectives: ME1071 is a maleic acid that inhibits metallo-b-lactamases (MBLs). We examined its ability to potentiate different carbapenems against MBL-producing Enterobacteriaceae in relation to its inhibition kinetics. Methods: Enterobacteriaceae an
Autor:
Kazunori Maebashi, Shoichi Murakami, Chizuko Kaji, Matsuhira Takashi, Kazuhiko Katayama, Naokazu Takeda, Tomoichiro Oka
Publikováno v:
Experimental Animals. 61:35-40
We isolated a novel murine norovirus (MNV), MT30-2 strain, from feces of conventional mice in Japan to evaluate the virucidal activity of four antiseptics. The MNV MT30-2 strain was inactivated by as little as 0.2% (w/v) povidone-iodine (PVP-I) and 0
Publikováno v:
Journal of Antimicrobial Chemotherapy. 65:37-45
Objectives: To further understand the mechanism of intermediate-level glycopeptide resistance, resulting from multiple endogenous mutations, in both laboratory-derived and clinically isolated Staphylococcus aureus. Methods: Laboratory-derived S. aure
Autor:
Kazunori Maebashi, Yumiko Sanbongi, Atsuyuki Shimizu, Takahisa Suzuki, Hiroshi Nagaso, Takashi Ida, Naomasa Gotoh
Publikováno v:
Microbiology and Immunology. 53:361-367
A total of 99 clinical isolates of metallo-ss-lactamase-negative Pseudomonas aeruginosa collected in Japan between 1998 and 2001 were studied for their susceptibilities to carbapenem agents and corresponding oprD gene mutations. The OprD sequence of
Autor:
Kazunori Maebashi, Atsuyuki Shimizu, Kimiko Ubukata, Takeshi Mikuniya, Masashi Niida, Muneo Hikida
Publikováno v:
Journal of Korean Medical Science
The in vitro antibacterial activities of oral cephem antibiotics and ketolide telithromycin against major respiratory pathogens possessing beta-lactam-resistant mutations (within the pbp gene) and/or macrolide-resistant genes (erm and mef) were exami