Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Kazunori Akimoto"'
Autor:
Ayako Maeda-Minami, Tomoki Nishikawa, Hideki Ishikawa, Michihiro Mutoh, Kazunori Akimoto, Yutaka Matsuyama, Yasunari Mano, Hiroji Uemura
Publikováno v:
Genes and Environment, Vol 45, Iss 1, Pp 1-8 (2023)
Abstract Background Prostate cancer is one of the most common cancers among men worldwide and the fourth most common cause of death. The number of prostate cancer cases and deaths is increasing every year because of population aging. This study aimed
Externí odkaz:
https://doaj.org/article/43662652bae640e3975d0df652abdd06
Autor:
Sayaka Nagamoto, Miyuki Agawa, Emi Tsuchitani, Kazunori Akimoto, Saki Kondo Matsushima, Yumi Kanegae
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Genome editing techniques such as CRISPR/Cas9 have both become common gene engineering technologies and have been applied to gene therapy. However, the problems of increasing the efficiency of genome editing and reducing off-target effects t
Externí odkaz:
https://doaj.org/article/9512eab23097458da241c37a9e457778
Autor:
Chotaro Onaga, Shoma Tamori, Izumi Matsuoka, Ayaka Ozaki, Hitomi Motomura, Yuka Nagashima, Tsugumichi Sato, Keiko Sato, Yuyun Xiong, Kazunori Sasaki, Shigeo Ohno, Kazunori Akimoto
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268799 (2022)
Estrogen receptor-positive (ER+) breast cancer intrinsically confers satisfactory clinical outcomes in response to endocrine therapy. However, a significant proportion of patients with ER+ breast cancer do not respond well to this treatment. Therefor
Externí odkaz:
https://doaj.org/article/e9147898669549f3baefc812aae176a9
Autor:
Yuji Kuramochi, Tomonari Awaya, Mami Matsuo-Takasaki, Miho Takami, Yuri An, Jingyue Li, Yasuko Hemmi, Tamami Wakabayashi, Yutaka Arai, Jun Inoue, Michiya Noguchi, Yukio Nakamura, Isao Asaka, Kazunori Akimoto, Megumu K. Saito, Yohei Hayashi
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102337- (2021)
Adrenoleukodystrophy (ALD) is an X-linked genetic disorder, characterized by demyelination in the central nervous system and adrenal insufficiency. Human induced pluripotent stem cell (hiPSC) lines derived from two Japanese male patients with ALD wer
Externí odkaz:
https://doaj.org/article/193cf00ce38e4473be44dc32ab02b779
Autor:
Yuka Nozaki, Hitomi Motomura, Shoma Tamori, Yumiko Kimura, Chotaro Onaga, Shotaro Kanai, Yuka Ishihara, Ayaka Ozaki, Yasushi Hara, Yohsuke Harada, Yasunari Mano, Tsugumichi Sato, Keiko Sato, Kazunori Sasaki, Hitoshi Ishiguro, Shigeo Ohno, Kazunori Akimoto
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235747 (2020)
Despite development of markers for identification of cancer stem cells, the mechanism underlying the survival and division of cancer stem cells in breast cancer remains unclear. Here we report that PKCλ expression was enriched in basal-like breast c
Externí odkaz:
https://doaj.org/article/b04cfed37c1b4f8ab79263c66008449a
Autor:
Li-Ping Liu, Dong-Xu Zheng, Zheng-Fang Xu, Hu-Cheng Zhou, Yun-Cong Wang, Hang Zhou, Jian-Yun Ge, Daisuke Sako, Mi Li, Kazunori Akimoto, Yu-Mei Li, Yun-Wen Zheng
Publikováno v:
Cells, Vol 11, Iss 1, p 70 (2021)
Amniotic epithelial stem cells (AESCs) are considered as potential alternatives to keratinocytes (KCs) in tissue-engineered skin substitutes used for treating skin damage. However, their clinical application is limited since similarities and distinct
Externí odkaz:
https://doaj.org/article/b1846d5cb47947d08a1f82e16b8fbf92
Autor:
Tomoyuki Yamanaka, Asako Tosaki, Masaru Kurosawa, Kazunori Akimoto, Tomonori Hirose, Shigeo Ohno, Nobutaka Hattori, Nobuyuki Nukina
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84036 (2013)
Cell polarity plays a critical role in neuronal differentiation during development of the central nervous system (CNS). Recent studies have established the significance of atypical protein kinase C (aPKC) and its interacting partners, which include P
Externí odkaz:
https://doaj.org/article/0b1eb06fb55f45fabcd8d32a2974d11e
Autor:
Tomonori Hirose, Daisuke Satoh, Hidetake Kurihara, Chiho Kusaka, Hiroko Hirose, Kazunori Akimoto, Taiji Matsusaka, Iekuni Ichikawa, Tetsuo Noda, Shigeo Ohno
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4194 (2009)
Glomerular visceral epithelial cells (podocytes) contain interdigitated processes that form specialized intercellular junctions, termed slit diaphragms, which provide a selective filtration barrier in the renal glomerulus. Analyses of disease-causing
Externí odkaz:
https://doaj.org/article/34963a7f651a4c7bb23169ef0133c434
Autor:
Takahiro Kasai, Shoma Tamori, Yuta Takasaki, Izumi Matsuoka, Ayaka Ozaki, Chika Matsuda, Yohsuke Harada, Kazunori Sasaki, Shigeo Ohno, Kazunori Akimoto
Publikováno v:
Biochemical and Biophysical Research Communications. 669:85-94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92794618cebf49f463d1552ddd3be815
https://doi.org/10.1016/j.bbrc.2023.05.086
https://doi.org/10.1016/j.bbrc.2023.05.086
Publikováno v:
Cancer Genomics & Proteomics (1109-6535); May/Jun2024, Vol. 21 Issue 3, p316-326, 11p