Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kazunobu Isogaya"'
Autor:
Mayu Arase, Yusuke Tamura, Natsumi Kawasaki, Kazunobu Isogaya, Ryo Nakaki, Anna Mizutani, Shuichi Tsutsumi, Hiroyuki Aburatani, Kohei Miyazono, Daizo Koinuma
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Epithelial-mesenchymal transition (EMT) is induced by transforming growth factor (TGF)-β and facilitates tumor progression. We here performed global mapping of accessible chromatin in the mouse mammary gland epithelial EpH4 cell line and it
Externí odkaz:
https://doaj.org/article/aa345726c13c45a3afa52b00864ccfe5
Publikováno v:
HeartRhythm Case Reports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47e0fbebe4333ac4d100ec524703746
http://europepmc.org/articles/PMC7573383
http://europepmc.org/articles/PMC7573383
Autor:
Borek Vojtesek, Kazunobu Isogaya, Curtis C. Harris, Natalia von Muhlinen, Fatima Alam, David P. Lane, Izumi Horikawa, Delphine Lissa
Publikováno v:
Oncogene
Cellular senescence is a hallmark of normal aging and aging-related syndromes, including the premature aging disorder Hutchinson-Gilford Progeria Syndrome (HGPS), a rare genetic disorder caused by a single mutation in the LMNA gene that results in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519fdaf03e42d735beb6dae97f323cec
https://doi.org/10.1038/s41388-017-0101-3
https://doi.org/10.1038/s41388-017-0101-3
Autor:
Daizo Koinuma, Akiyoshi Komuro, Masato Morikawa, Caname Iwata, Hiroyuki Mano, Yasushi Ino, Keiko Yuki, Kazunobu Isogaya, Nobuhito Saito, Akitake Mukasa, Hiroyuki Aburatani, Hitoshi Okada, Erna Raja, Kohei Miyazono, Manabu Soda, Melissa Ranjit, Tomoki Todo, Hiromichi Suzuki, Atsushi Natsume
Publikováno v:
International Journal of Cancer. 142:1627-1639
Glioblastoma is one of the most malignant forms of cancer, for which no effective targeted therapy has been found. Although The Cancer Genome Atlas has provided a list of fusion genes in glioblastoma, their role in progression of glioblastoma remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f46206bb3fcdc3efb7a29f915fd8255
https://doi.org/10.1002/ijc.31179
https://doi.org/10.1002/ijc.31179
Autor:
Kye-Yoon Park, Katsuhiro Anami, Ana I. Robles, Abdul M. Mondal, Yukiharu Hiyoshi, Izumi Horikawa, Kaori Fujita, Manuel Serrano, Han Li, Kazunobu Isogaya, Curtis C. Harris
Publikováno v:
Cell Death & Differentiation. 24:1017-1028
p53 functions to induce cellular senescence, which is incompatible with self-renewal of pluripotent stem cells such as induced pluripotent stem cells (iPSC) and embryonic stem cells (ESC). However, p53 also has essential roles in these cells through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe136265d4b4feb449f98e6486d41f6
https://doi.org/10.1038/cdd.2017.48
https://doi.org/10.1038/cdd.2017.48
Autor:
Kiyotaka Nagahama, Kazunobu Isogaya, Sayaka Funata, Isao Kataoka, Nobutsugu Abe, Hirohisa Takeuchi, Junji Shibahara
Publikováno v:
Annals of diagnostic pathology. 44
Gastric adenocarcinoma (GA) with enteroblastic differentiation is a subset of gastric cancer with poor prognosis. RNA-Seq data of The Cancer Genome Atlas of GA (TCGA-STAD) revealed a positive correlation between SALL4, a representative enteroblastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8209d4ddcc5975b09c058937b9ef5c4d
https://pubmed.ncbi.nlm.nih.gov/31862523
https://pubmed.ncbi.nlm.nih.gov/31862523
Autor:
Akiyoshi, Komuro, Erna, Raja, Caname, Iwata, Manabu, Soda, Kazunobu, Isogaya, Keiko, Yuki, Yasushi, Ino, Masato, Morikawa, Tomoki, Todo, Hiroyuki, Aburatani, Hiromichi, Suzuki, Melissa, Ranjit, Atsushi, Natsume, Akitake, Mukasa, Nobuhito, Saito, Hitoshi, Okada, Hiroyuki, Mano, Kohei, Miyazono, Daizo, Koinuma
Publikováno v:
International journal of cancer. 142(8)
Glioblastoma is one of the most malignant forms of cancer, for which no effective targeted therapy has been found. Although The Cancer Genome Atlas has provided a list of fusion genes in glioblastoma, their role in progression of glioblastoma remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba643115fb7ae062767b9f5b34b25d94
https://pubmed.ncbi.nlm.nih.gov/29193056
https://pubmed.ncbi.nlm.nih.gov/29193056
Autor:
Daizo Koinuma, Kazunobu Isogaya, Kohei Miyazono, Shuichi Tsutsumi, Hiroyuki Aburatani, R. K. Saito, Keiji Miyazawa
Publikováno v:
Cell Research
Thyroid transcription factor-1 (TTF-1, also known as NKX2-1) is a tissue-specific transcription factor in lung epithelial cells. Although TTF-1 inhibits the epithelial-to-mesenchymal transition induced by transforming growth factor-β (TGF-β) in lun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce03b985e44095ee6b9943884a92968
https://doi.org/10.1038/cr.2014.97
https://doi.org/10.1038/cr.2014.97
Autor:
Masao Saitoh, Kazunobu Isogaya, Hiroaki Ikushima, Takeo Kubota, Kunio Miyake, Keiji Miyazawa, Kohei Miyazono, Mitsuyoshi Motizuki
Publikováno v:
Journal of Biological Chemistry. 288:18911-18922
Transforming growth factor (TGF)-β plays crucial roles in embryonic development and adult tissue homeostasis by eliciting various cellular responses in target cells. TGF-β signaling is principally mediated through receptor-activated Smad proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9d10340d957814c822e360f0be4ed5
https://doi.org/10.1074/jbc.m113.480996
https://doi.org/10.1074/jbc.m113.480996
Autor:
Tsubasa Sakurai, Daizo Koinuma, Kohei Miyazono, Satoshi Sakai, Kazunobu Isogaya, Yasuyuki Morishita, Masato Morikawa, Shogo Ehata
Publikováno v:
Oncogene
RNA-binding proteins provide a new layer of posttranscriptional regulation of RNA during cancer progression. We identified RNA-binding motif protein 47 (RBM47) as a target gene of transforming growth factor (TGF)-beta in mammary gland epithelial cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e8fcec84c4807b3e7a61f261ebd194
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-305331
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-305331
