Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Kazunari K. Yokoyama"'
Publikováno v:
Cells, Vol 13, Iss 19, p 1648 (2024)
Control of oxidation/antioxidation homeostasis is important for cellular protective functions, and disruption of the antioxidation balance by exogenous and endogenous ligands can lead to profound pathological consequences of cancerous commitment with
Externí odkaz:
https://doaj.org/article/025df5fc7cae4cf7a65b159659c29a32
Autor:
Kenly Wuputra, Ming-Ho Tsai, Kohsuke Kato, Chia-Chen Ku, Jia-Bin Pan, Ya-Han Yang, Shigeo Saito, Chun-Chieh Wu, Ying-Chu Lin, Kuang-Hung Cheng, Kung-Kai Kuo, Michiya Noguchi, Yukio Nakamura, Tohru Yoshioka, Deng-Chyang Wu, Chang-Shen Lin, Kazunari K. Yokoyama
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-25 (2023)
Abstract Background Crosstalk between the aryl hydrocarbon receptor (AhR) and nuclear factor (erythroid-derived 2)-like 2 (Nrf2) signaling is called the “AhR–Nrf2 gene battery”, which works synergistically in detoxification to support cell surv
Externí odkaz:
https://doaj.org/article/f50a183d230244a7b496aebd1acd211c
Autor:
Kenly Wuputra, Chia-Chen Ku, Kohsuke Kato, Deng-Chyang Wu, Shigeo Saito, Kazunari K. Yokoyama
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract It is postulated as a general concept of cancer stem cells (CSCs) that they can produce cancer cells overtly and repopulate cancer progenitor cells indefinitely. The CSC niche is part of a specialized cancer microenvironment that is importan
Externí odkaz:
https://doaj.org/article/086755e83663415891d7d24d0c0f5eed
Autor:
Chia-Chen Ku, Kenly Wuputra, Kohsuke Kato, Jia-Bin Pan, Chia-Pei Li, Ming-Ho Tsai, Michiya Noguchi, Yukio Nakamura, Chung-Jung Liu, Te-Fu Chan, Ming-Feng Hou, Shigeharu Wakana, Yang-Chang Wu, Chang-Shen Lin, Deng-Chyang Wu, Kazunari K. Yokoyama
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Background The cerebellum is the sensitive region of the brain to developmental abnormalities related to the effects of oxidative stresses. Abnormal cerebellar lobe formation, found in Jun dimerization protein 2 (Jdp2)-knockout (KO) mice, is
Externí odkaz:
https://doaj.org/article/b8496ffdb402479db4a2d01cb6b9945a
Autor:
Ker-Kong Chen, Moeko Minakuchi, Kenly Wuputra, Chia-Chen Ku, Jia-Bin Pan, Kung-Kai Kuo, Ying-Chu Lin, Shigeo Saito, Chang-Shen Lin, Kazunari K. Yokoyama
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-22 (2020)
Abstract Triggered in response to external and internal ligands in cells and animals, redox homeostasis is transmitted via signal molecules involved in defense redox mechanisms through networks of cell proliferation, differentiation, intracellular de
Externí odkaz:
https://doaj.org/article/765a8bf7651344a5ba4f8542c290d3c5
Autor:
Kenly Wuputra, Chia-Chen Ku, Deng-Chyang Wu, Ying-Chu Lin, Shigeo Saito, Kazunari K. Yokoyama
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-24 (2020)
Abstract Human pluripotent embryonic stem cells have two special features: self-renewal and pluripotency. It is important to understand the properties of pluripotent stem cells and reprogrammed stem cells. One of the major problems is the risk of rep
Externí odkaz:
https://doaj.org/article/bbea83d8a3f846d884cf96409bb4ee49
Autor:
Chia-Chen Ku, Kenly Wuputra, Jia-Bin Pan, Chia-Pei Li, Chung-Jung Liu, Yi-Chang Liu, Shigeo Saito, Te-Fu Chan, Chang-Shen Lin, Deng-Chyang Wu, Kazunari K. Yokoyama
Publikováno v:
Cells, Vol 11, Iss 2, p 184 (2022)
There is considerable cellular diversity in the human stomach, which has helped to clarify cell plasticity in normal development and tumorigenesis. Thus, the stomach is an interesting model for understanding cellular plasticity and for developing pro
Externí odkaz:
https://doaj.org/article/06d13911944e4303a01881a0b0c991de
Autor:
Kenly Wuputra, Chang-Shen Lin, Ming-Ho Tsai, Chia-Chen Ku, Wen-Hsin Lin, Ya-Han Yang, Kung-Kai Kuo, Kazunari K. Yokoyama
Publikováno v:
Inflammation and Regeneration, Vol 37, Iss 1, Pp 1-7 (2017)
Abstract The cancer stem cell (CSC) hypothesis postulates that cancer originates from the malignant transformation of stem/progenitor cells and is considered to apply to many cancers, including liver cancer. Identification that CSCs are responsible f
Externí odkaz:
https://doaj.org/article/3d63e057c1f04068ae979b4ba9c9e8a0
Autor:
Shigeo Saito, Ying-Chu Lin, Ming-Ho Tsai, Chang-Shen Lin, Yoshinobu Murayama, Ryuji Sato, Kazunari K. Yokoyama
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 31, Iss 6, Pp 279-286 (2015)
Eukaryotic organisms require oxygen homeostasis to maintain proper cellular function for survival. During conditions of low oxygen tension (hypoxia), cells activate the transcription of genes that induce an adaptive response, which supplies oxygen to
Externí odkaz:
https://doaj.org/article/0a8690e36887413496895de7b8ac8513
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 28, Iss 6, Pp 352-354 (2012)
Externí odkaz:
https://doaj.org/article/8cd5b7113ee94486bf0ad84673c3c9fc