Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Kazunari Higa"'
Autor:
Asahi Kitamura, Masahito Yamamoto, Hidetomo Hirouchi, Genji Watanabe, Shuichiro Taniguchi, Sayo Sekiya, Satoshi Ishizuka, Juhee Jeong, Kazunari Higa, Shuichiro Yamashita, Shinichi Abe
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0301080 (2024)
Entheses are classified into three types: fibrocartilaginous, fibrous, and periosteal insertions. However, the mechanism behind the development of fibrous entheses and periosteal insertions remains unclear. Since both entheses are part of the temporo
Externí odkaz:
https://doaj.org/article/d8a9a240dbf94d1ab5b07eeac6131d67
Autor:
Kazunari Higa, Reona Kimoto, Takashi Kojima, Murat Dogru, Wolfgang G. K. Müller-Lierheim, Jun Shimazaki
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 523 (2024)
The temporal change in concentration of a novel medicine, Latanoprost (LP), was evaluated in the aqueous humor of rats (6–8-week-old Jcl:Wister rats) when delivered in a very-high-molecular-weight hyaluronic acid (vHiHA) eye drop. Animals were rand
Externí odkaz:
https://doaj.org/article/52bc38743171464b831e18bae76cff0d
Autor:
Sota Nishisako, Takefumi Yamaguchi, Yuki Kusano, Kazunari Higa, Dai Aoki, Chiaki Sasaki, Jun Shimazaki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Descemet's stripping automated endothelial keratoplasty (DSAEK) is used for treating corneal endothelial dysfunction, and the postoperative visual acuity outcome depends on the thickness of the graft. We created a simple nomogram using facto
Externí odkaz:
https://doaj.org/article/74574487c03a4d4ebbc765fdf9b4b887
Autor:
Saki Sakakura, Emi Inagaki, Yuichiro Ochiai, Masatoshi Yamamoto, Naofumi Takai, Taeko Nagata, Kazunari Higa, Yasunori Sato, Hiroshi Toshida, Dogru Murat, Masatoshi Hirayama, Yoko Ogawa, Kazuno Negishi, Shigeto Shimmura
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16510 (2023)
Tear film instability is a major cause of dry eye disease. In order to treat patients with short tear film breakup time (TBUT)-type dry eye, the development of tear film stabilizing agents is essential. However, the lack of an appropriate animal mode
Externí odkaz:
https://doaj.org/article/6b5da6493af744c38b9ce59bccb497e5
Autor:
Takaaki Inaba, Mayumi Ohnishi-Kameyama, Ying Liu, Yasuhisa Tanaka, Masuko Kobori, Shusaku Tamaki, Tomotaka Ito, Kazunari Higa, Jun Shimazaki, Kazuo Tsubota
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Anti-oxidant properties of polyphenols have been gaining medical attention as a preventive factor against aging and/or lifestyle diseases. In this study, we examined the anti-oxidant activity of quercetin improved tear function through its effects on
Externí odkaz:
https://doaj.org/article/ff2eaecf0b44475b9ef25694d69e12a2
Autor:
Hikari Amemiya, Masahito Yamamoto, Kazunari Higa, Genji Watanabe, Shuichiro Taniguchi, Kei Kitamura, Juhee Jeong, Nobuaki Yanagisawa, Ken-ichi Fukuda, Shinichi Abe
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6634 (2023)
Myostatin (Myo) is known to suppress skeletal muscle growth, and was recently reported to control tendon homeostasis. The purpose of the present study was to investigate the regulatory involvement of Myo in the myotendinous junction (MTJ) in vivo and
Externí odkaz:
https://doaj.org/article/47c1f617aff84550945c0d121614ad27
Autor:
Murat Dogru, Takashi Kojima, Kazunari Higa, Ayako Igarashi, Haruka Kudo, Wolfgang G. K. Müller-Lierheim, Kazuo Tsubota, Kazuno Negishi
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 2, p 544 (2023)
Anti-glaucoma eye drop treatment often induces ocular surface problems, including dry eyes, and may be associated with poor medication compliance. This study aimed to investigate the effects of a novel high molecular weight hyaluronic acid and Latano
Externí odkaz:
https://doaj.org/article/df26f2484a8041e1acb3629fa17b4881
Autor:
Sota Nishisako, Takefumi Yamaguchi, Masatoshi Hirayama, Kazunari Higa, Dai Aoki, Chiaki Sasaki, Hisashi Noma, Jun Shimazaki
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
AimsTo identify donor-related risk factors associated with graft endothelial failure and postoperative endothelial cell density (ECD) reduction after Descemet's stripping automated endothelial keratoplasty (DSAEK).MethodsThis was a single-center retr
Externí odkaz:
https://doaj.org/article/7c6ea900b6db41bd811341c48ccaddea
Autor:
Shin Hatou, Tomoko Sayano, Kazunari Higa, Emi Inagaki, Yuji Okano, Yasunori Sato, Hideyuki Okano, Kazuo Tsubota, Shigeto Shimmura
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102497- (2021)
Objective: In order to provide regenerative therapy for millions of patients suffering from corneal blindness globally, we derived corneal endothelial cell substitute (CECSi) cells from induced pluripotent stem cells (iPSCs) to treat corneal edema du
Externí odkaz:
https://doaj.org/article/f5199bef44374887939298d2261c86e9
Autor:
Kazunari Higa, Junko Higuchi, Reona Kimoto, Hideyuki Miyashita, Jun Shimazaki, Kazuo Tsubota, Shigeto Shimmura
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102012- (2020)
Corneal epithelial stem cells reside in the limbal area between the cornea and conjunctiva. We examined the potential use of limbal organoids as a source of transplantable limbal stem cells. After treating tissue with collagenase, limbal cells were s
Externí odkaz:
https://doaj.org/article/359d1e61029d4a46a63a79db0fee64b2