Zobrazeno 1 - 10
of 450
pro vyhledávání: '"Kazunari, Akiyoshi"'
Autor:
Daisuke Muraoka, Meng Ling Moi, Osamu Muto, Takaaki Nakatsukasa, Situo Deng, Chieko Takashima, Rui Yamaguchi, Shin-ichi Sawada, Haruka Hayakawa, Thi Thanh Ngan Nguyen, Yasunari Haseda, Takatoshi Soga, Hirokazu Matsushita, Hiroaki Ikeda, Kazunari Akiyoshi, Naozumi Harada
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Vaccine-induced T cells and neutralizing antibodies are essential for protection against SARS-CoV-2. Previously, we demonstrated that an antigen delivery system, pullulan nanogel (PNG), delivers vaccine antigen to lymph node medullary macrop
Externí odkaz:
https://doaj.org/article/4fe9413ee54f426598c15d2588d785e7
Autor:
Mako Kobayashi, Jun Negishi, Naoki Ishida, Yoshihide Hashimoto, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida
Publikováno v:
Science and Technology of Advanced Materials, Vol 25, Iss 1 (2024)
Decellularized tissues have been used as implantable materials for tissue regeneration because of their high biofunctionality. We have reported that high hydrostatic pressured (HHP) decellularized tissue developed in our laboratory exhibits good in v
Externí odkaz:
https://doaj.org/article/b5108176b71340cfbac82312d8fd78df
Autor:
Shingo Umemoto, Rika Nakahashi-Ouchida, Yoshikazu Yuki, Shiho Kurokawa, Tomonori Machita, Yohei Uchida, Hiromi Mori, Tomoyuki Yamanoue, Takehiko Shibata, Shin-ichi Sawada, Kazuya Ishige, Takashi Hirano, Kohtaro Fujihashi, Kazunari Akiyoshi, Yosuke Kurashima, Daisuke Tokuhara, Peter B Ernst, Masashi Suzuki, Hiroshi Kiyono
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Respiratory syncytial virus (RSV) is a leading cause of upper and lower respiratory tract infection, especially in children and the elderly. Various vaccines containing the major transmembrane surface proteins of RSV (proteins F and G) have
Externí odkaz:
https://doaj.org/article/27bafa5bb1384d08a0dc201789536623
Autor:
Kenta Yamamoto, Shin-Ichi Sawada, Satoru Shindo, Shin Nakamura, Young M. Kwon, Nazanin Kianinejad, Saynur Vardar, Maria Hernandez, Kazunari Akiyoshi, Toshihisa Kawai
Publikováno v:
Gels, Vol 10, Iss 6, p 377 (2024)
Osteoclast stimulatory transmembrane protein (OC-STAMP) plays a pivotal role in the promotion of cell fusion during osteoclast differentiation (osteoclastogenesis) in the context of pathogenic bone resorption. Thus, it is plausible that the suppressi
Externí odkaz:
https://doaj.org/article/c641e1ddfb294b369c85bdaeb6f10516
Autor:
Tetsuya Adachi, Yoshiro Tahara, Kenta Yamamoto, Toshiro Yamamoto, Narisato Kanamura, Kazunari Akiyoshi, Osam Mazda
Publikováno v:
Gels, Vol 10, Iss 3, p 206 (2024)
Novel functional biomaterials are expected to bring about breakthroughs in developing immunotherapy and regenerative medicine through their application as drug delivery systems and scaffolds. Nanogels are defined as nanoparticles with a particle size
Externí odkaz:
https://doaj.org/article/2f71342c17bf42b68343a8afd80b294f
Autor:
Worachat Namangkalakul, Shigenori Nagai, Chengxue Jin, Ken-ichi Nakahama, Yuki Yoshimoto, Satoshi Ueha, Kazunari Akiyoshi, Kouji Matsushima, Tomoki Nakashima, Masaki Takechi, Sachiko Iseki
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Fibroblast growth factor (FGF) signaling plays essential roles in various biological events. FGF18 is one of the ligands to be associated with osteogenesis, chondrogenesis and bone healing. The mouse critical-sized calvarial defect healing induced by
Externí odkaz:
https://doaj.org/article/81cdec4b4dc8450da5d5cbe4e3b6cf0d
Publikováno v:
FEBS Open Bio, Vol 12, Iss 6, Pp 1178-1187 (2022)
Extracellular vesicles (EVs) have potential biomedical applications, particularly as a means of transport for therapeutic agents. There is a need for rapid and efficient EV‐liposome membrane fusion that maintains the integrity of hybrid EVs. We rec
Externí odkaz:
https://doaj.org/article/eb0f09b88d7944199d2eee43a6fc8d4f
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest gastrointestinal cancers with a 5-year survival rate of less than 10%. Biomarkers for early PDAC detection are useful in treating patients with PDAC. Extracellular ve
Externí odkaz:
https://doaj.org/article/beecb7c34e294c41935cfdb38a7f0c4e
Autor:
Kohei Yabuuchi, Mika Suzuki, Chen Liang, Yoshihide Hashimoto, Tsuyoshi Kimura, Kazunari Akiyoshi, Akio Kishida
Publikováno v:
Gels, Vol 9, Iss 11, p 866 (2023)
Nanogels are candidate biomaterials for tissue engineering and drug delivery. In the present study, a cholesterol–hyaluronic acid hydrogel was developed, and the pro-inflammatory response of macrophages to the hydrogel was investigated to determine
Externí odkaz:
https://doaj.org/article/c8b596fcaea445d0974d23aa7271fbe7
Autor:
Cangyou Xie, Fatma Rashed, Yosuke Sasaki, Masud Khan, Jia Qi, Yuri Kubo, Yoshiro Matsumoto, Shinichi Sawada, Yoshihiro Sasaki, Takashi Ono, Tohru Ikeda, Kazunari Akiyoshi, Kazuhiro Aoki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9751 (2023)
The receptor activator of NF-κB ligand (RANKL)-binding peptide is known to accelerate bone morphogenetic protein (BMP)-2-induced bone formation. Cholesterol-bearing pullulan (CHP)-OA nanogel-crosslinked PEG gel (CHP-OA nanogel-hydrogel) was shown to
Externí odkaz:
https://doaj.org/article/ca83ce7b75af4656877af98a271bdb56