Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Kazunao Kondo"'
Autor:
Yui Suganuma, Chiho Sumi-Ichinose, Taiki Kano, Kazuhisa Ikemoto, Taei Matsui, Hiroshi Ichinose, Kazunao Kondo
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 3, Pp 173-179 (2022)
Quinonoid dihydropteridine reductase (QDPR) regenerates tetrahydrobiopterin (BH4), which is an essential cofactor for catecholamine and serotonin (5-hydroxytryptamine, 5-HT) biosynthesis. Serotonin is known as an important platelet agonist, but its r
Externí odkaz:
https://doaj.org/article/b9298d8d41f146c1bcc2ec802ea07199
Publikováno v:
Folia Pharmacologica Japonica. 158:134-137
Autor:
Chiho Sumi‐Ichinose, Yui Suganuma, Taiki Kano, Kazuhisa Ikemoto, Noriko Ihira, Hiroshi Ichinose, Kazunao Kondo
Publikováno v:
J Inherit Metab Dis. 45:621-634
6R-L-erythro-5,6,7,8-tetrahydrobiopterin (BH4) is an essential cofactor for aromatic L-amino acid hydroxylases, including tyrosine hydroxylase (TH), alkylglycerol monooxygenase, and three types of nitric oxide (NO) synthases (NOS). Sepiapterin reduct
Autor:
Katsuya Miyajima, Yusuke Sudo, Sho Sanechika, Yoshitaka Hara, Mieko Horiguchi, Feng Xu, Minori Suzuki, Satoshi Hara, Koichi Tanda, Ken‐ichi Inoue, Masahiko Takada, Nozomu Yoshioka, Hirohide Takebayashi, Masayo Mori‐Kojima, Masahiro Sugimoto, Chiho Sumi‐Ichinose, Kazunao Kondo, Keizo Takao, Tsuyoshi Miyakawa, Hiroshi Ichinose
Publikováno v:
Journal of neurochemistry. 161(Issue 2):129-145
Increasing evidence suggests the involvement of peripheral amino acid metabolism in the pathophysiology of neuropsychiatric disorders, whereas the molecular mechanisms are largely unknown. Tetrahydrobiopterin (BH4) is a cofactor for enzymes that cata
Autor:
Takeshi Takayanagi, Yoko Kaneko S., Hiroshi Nagasaki, Yu Kodani, Akira Nakashima, Keiji Mori, Atsushi Suzuki, Mitsuyasu Itoh, Kazunao Kondo, Toshiharu Nagatsu, Miyuki Ota, Akira Ota
Publikováno v:
Fujita Medical Journal, Vol 1, Iss 1, Pp 1-5 (2016)
Objectives: According to our previous work, aripiprazole exerted a protective effect on hydrogen peroxide (H2O2)-treated PC12 cells; haloperidol did not. Because aripiprazole has distinct affinities to a set of neurotransmitter receptor subtypes, thi
Externí odkaz:
https://doaj.org/article/eeb57ba85a9d4a5ea3bfd9bbd9855a6a
Publikováno v:
Journal of Pharmacological Sciences, Vol 114, Iss 1, Pp 17-24 (2010)
5R-l-Erythro-5,6,7,8-tetrahydrobiopterin (BH4) is an essential cofactor for tyrosine hydroxylase (TH). Recently, a type of dopa-responsive dystonia (DRD) (DYT5, Segawa’s disease) was revealed to be caused by dominant mutations of the gene encoding
Externí odkaz:
https://doaj.org/article/6cf2608cf0b942ae9b155bb012d06549
Autor:
Toshiharu Nagatsu, Taiki Kano, Chiho Sumi-Ichinose, Kazunao Kondo, Yui Suganuma, Noriko Ihira, Kazuhisa Ikemoto
Publikováno v:
Journal of biochemistry. 170(4)
Neopterin (NP), biopterin (BP) and monapterin (MP) exist in saliva. The physiological role of salivary NP as well as the pathophysiological role of increased NP in the immune-activated state has been unclear. Saliva is a characteristic specimen diffe
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:3-S38
Autor:
Chiho Sumi-Ichinose, Yui Suganuma, Taiki Kano, Kazuhisa Ikemoto, Noriko Ihira, Hiroshi Ichinose, Kazunao Kondo
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:2-O
Publikováno v:
Clinical Pharmacology in Drug Development
We evaluated the pharmacokinetics and pharmacodynamics of prasugrel used in combination with aspirin in healthy Japanese subjects. All subjects received aspirin 100 mg/day. Subsequently, in the single-administration study, 23 subjects also received p