Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Kazumi Toyama"'
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Unripe peach ( Prunus persica ) extract ameliorates damage from UV irradiation and improved collagen XVIII expression in 3D skin model
Autor: Toshitaka Oohashi, Tomohiro Hakozaki, Kazumi Toyama, Chieko Soh, Hideki Iwano, Tomoko Yonezawa, Ryusuke Momota, Steven Zhao, Shigetoyo Sawaki
Publikováno v: Journal of Cosmetic Dermatology. 18:1507-1515
Introduction Collagen type XVIII regulates cellular activities of adjacent cells at the dermal-epidermal junction (DEJ). To investigate its possible changes during aging, we compared its mRNA levels and protein localization in skin samples from femal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66a7ed38db50358d58cfc50f0d823e1
https://doi.org/10.1111/jocd.12841
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2
Phlorizin, an Active Ingredient ofEleutherococcus senticosus, Increases Proliferative Potential of Keratinocytes with Inhibition of MiR135b and Increased Expression of Type IV Collagen
Autor: Akira Date, Hye-Ryung Choi, Kyoung-Chan Park, Youngsoo Kim, Kazumi Toyama, Seung-Hye Yang, Hyun-Sun Lee, Kyung-Mi Nam, Jongsung Lee
Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Oxidative Medicine and Cellular Longevity
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
E. senticosusextract (ESE), known as antioxidant, has diverse pharmacologic effects. It is also used as an antiaging agent for the skin and phlorizin (PZ) is identified as a main ingredient. In this study, the effects of PZ on epidermal stem cells we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752004c7de97acb30da242148567edd1
https://doi.org/10.1155/2016/3859721
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3
Aging rather than sun exposure is a major determining factor for the density ofmiR-125b-positive epidermal stem cells in human skin
Autor: Tamae Wada, Shinya Toyokuni, Ayaka Hirao, Akira Kawada, Kazumi Toyama, Shenqi Wang, Chieko Soh, Li Jiang
Publikováno v: Pathology International. 65:415-419
Sunlight exposure and aging are two major factors in the deterioration of skin function. In the present study, we used eighty formalin-fixed human skin samples from sun-exposed and unexposed areas from old and young individuals to evaluate the presen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ab13ffd8ad1d86d00e38aef1fd66388
https://doi.org/10.1111/pin.12320
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4
Age-induced and photoinduced changes in gene expression profiles in facial skin of Caucasian females across 6 decades of age
Autor: Joyce Y. Tung, Alexa B. Kimball, Nikki E. Annunziata, Raghu Kainkaryam, Dionne D. Swift, Heather L. Rocchetta, Xianghong Yan, Robert J. Isfort, Makio Tamura, Jun Xu, Emily D. Conley, Robert Lloyd Binder, Bradley B. Jarrold, Lisa Ann Mullins, Chieko Soh, Charles C. Bascom, Neil Houston, Rosemarie Osborne, Kazumi Toyama, Jay P. Tiesman, Maria B. Alora-Palli
Publikováno v: Journal of the American Academy of Dermatology. 78(1)
Background Intrinsic and extrinsic factors, including ultraviolet irradiation, lead to visible signs of skin aging. Objective We evaluated molecular changes occurring in photoexposed and photoprotected skin of white women 20 to 74 years of age, some
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e347eed34a324bfaa6ddcb17fe48ad93
https://pubmed.ncbi.nlm.nih.gov/29146147
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5
Phloridzin isolated from Acanthopanax senticosus promotes proliferation of α6 integrin (CD 49f) and β1 integrin (CD29) enriched for a primary keratinocyte population through the ERK-mediated mTOR pathway
Autor: Jongsung Lee, Youngsoo Kim, Kazumi Toyama, Eunsun Jung, Deokhoon Park, Jienny Lee, Akira Date
Publikováno v: Archives of Dermatological Research. 305:747-754
We investigated the proliferative effect of a Acanthopanax senticosus extract (ASE) on human CD49f(+)/CD29(+) keratinocytes and isolated phloridzin from A. senticosus as an active compound. In addition, the possible mechanisms of action were examined
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8dee2cc9f0f0f7a37de92da93b9e3f
https://doi.org/10.1007/s00403-013-1398-6
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6
Aging rather than sun exposure is a major determining factor for the density of miR-125b-positive epidermal stem cells in human skin
Autor: Shinya, Toyokuni, Li, Jiang, Shenqi, Wang, Ayaka, Hirao, Tamae, Wada, Chieko, Soh, Kazumi, Toyama, Akira, Kawada
Publikováno v: Pathology international. 65(8)
Sunlight exposure and aging are two major factors in the deterioration of skin function. In the present study, we used eighty formalin-fixed human skin samples from sun-exposed and unexposed areas from old and young individuals to evaluate the presen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21c9a6834528516339c6c68ee84b11cf
https://pubmed.ncbi.nlm.nih.gov/26081223
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7
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10
[Trastuzumab treatment for breast cancer]
Autor: Hiroyasu, Yamashiro, Kazumi, Toyama, Hiroko, Bando, Shigehira, Saji, Masakazu, Toi
Publikováno v: Nihon rinsho. Japanese journal of clinical medicine. 62(7)
Trastuzumab is a recombinant humanized monoclonal antibody directed against the HER-2. HER-2 is overexpressed in 20-25% of invasive breast cancer and known as poor prognostic factor and its status of a tumor is related to response to trastuzumab. Com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6c14e9bb6d68a74b06e6db5ffab064ba
https://pubmed.ncbi.nlm.nih.gov/15283148
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