Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kazumi Nishijima"'
Autor:
Tetsuya Terasaki, Michihisa Koyama, Carlos A. Del Carpio, Ewa Broclawik, Akira Endou, Qiang Pei, Momoji Kubo, Akira Miyamoto, Kazumi Nishijima, Hideyuki Tsuboi
Publikováno v:
MATERIALS TRANSACTIONS. 48:735-739
ATP binding subunit is known as a subunit of ABC transporter, providing energy through the binding of ATP with the subunit and the subsequent hydrolysis reaction of the bound ATP. In this study, density functional theory (DFT) method was used to stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edf0f7b5bedba90e98399a7de0c1bd49
https://doi.org/10.2320/matertrans.48.735
https://doi.org/10.2320/matertrans.48.735
Autor:
Tetsuya Terasaki, Akira Miyamoto, Momoji Kubo, Michihisa Koyama, Carlos A. Del Carpio, Kotaro Okushi, Kazumi Nishijima, Ewa Broclawik, Hideyuki Tsuboi
Publikováno v:
International Congress Series. 1284:296-301
Understanding pharmacokinetics in the human body is of the utmost relevance in various stages of medical services. However, a problem arises when conveying pharmacokinetic knowledge to people unfamiliar with the discipline. To overcome this communica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1d5adda38c8ea99782916e270fd7cb5
https://doi.org/10.1016/j.ics.2005.06.025
https://doi.org/10.1016/j.ics.2005.06.025
Synthesis and diuretic activity of 2,3-dihydro-4(1H)-quinolinone 4-oxime-O-sulfonic acid derivatives
Autor:
Kikuo Ohtomo, Hidemitsu Nishida, Masahiro Mizota, Yoshiaki Yamashita, Kazuo Kato, Kazumi Nishijima, Naofumi Sato, Tomoaki Shinkawa, Sotaro Miyano, Yoshiaki Onuki
Publikováno v:
European Journal of Medicinal Chemistry. 33:267-277
The diuretic activity of 6-chloro-2,3-dihydro-1-propionyl-4(1H)-quinolinone 4-oxime 1 (M12285) was previously shown to derive from a 6-chloro-2,3-dihydro-1-propionyl-4(1H)-quinolinone 4-oxime-O-sulfonic acid salt as a rat metabolite. Thus, in the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df6f9d5c6927c3be353d893f254f9715
https://doi.org/10.1016/s0223-5234(98)80061-5
https://doi.org/10.1016/s0223-5234(98)80061-5
Autor:
Yoshio Katsuya, Kazumi Nishijima
Publikováno v:
Nihon Kessho Gakkaishi. 44:389-391
The Pharmaceutical Industry Beamline was constructed by the Pharmaceutical Consortium for Protein Structure Analysis which was established in April 2001. The consortium is composed of 22 pharmaceutical companies affiliating with the Japan Pharmaceuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93bf564f400b865953cdbf713d3ea736
https://doi.org/10.5940/jcrsj.44.389
https://doi.org/10.5940/jcrsj.44.389
Autor:
Tomoaki Shinkawa, Fumiaki Yamasaki, Masanori Nakakuki, Kazumi Nishijima, Tatsuto Notsu, Masashi Imai, Koji Yoshitomi
Publikováno v:
European Journal of Pharmacology. 238:317-325
We investigated the mechanism of action of a novel ‘high ceiling’ diuretic, M17055, in in vivo clearance studies with anesthetized dogs during water diuresis and in vitro microperfusion studies of isolated rabbit renal tubules. In the clearance s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb0c33aab1645054d518c0e0ff03e0b
https://doi.org/10.1016/0014-2999(93)90863-d
https://doi.org/10.1016/0014-2999(93)90863-d
Autor:
Masahiro Mizota, A. Kikuchi, F Yamasaki, Y. Orita, Akio Uemura, T. Skinkawa, Nakakuki M, Kazumi Nishijima
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5bcff20f1e8df6608d3aae77c5a319d
https://doi.org/10.1002/chin.199313303
https://doi.org/10.1002/chin.199313303
Autor:
Tomoaki Shinkawa, Naofumi Sato, Yoshiaki Yamashita, Yoshiaki Onuki, Hidemitsu Nishida, Sotaro Miyano, Masahiro Mizota, Kazuo Kato, Kikuo Ohtomo, Kazumi Nishijima
Publikováno v:
ChemInform. 29
The diuretic activity of 6-chloro-2,3-dihydro-1-propionyl-4(1H)-quinolinone 4-oxime 1 (M12285) was previously shown to derive from a 6-chloro-2,3-dihydro-1-propionyl-4(1H)-quinolinone 4-oxime-O-sulfonic acid salt as a rat metabolite. Thus, in the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::919cc932c359749537da38940033bda6
https://doi.org/10.1002/chin.199837164
https://doi.org/10.1002/chin.199837164
Autor:
Hidemitsu Nishida, Yoshiaki Onuki, Ichirou Yamamoto, Hitoshi Inaba, Kazumi Nishijima, Tomoaki Shinkawa, S. Miyano, Manabu Ito
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12dd26ecd1a73ba0577b1b8e08f83517
https://doi.org/10.1002/chin.199910270
https://doi.org/10.1002/chin.199910270
Autor:
Yoshiaki Onuki, Kazumi Nishijima, Yoshiaki Yamashita, Sotaro Miyano, Hidemitsu Nishida, Masahiro Mizota, Manabu Ito
Publikováno v:
ChemInform. 31
In order to investigate the origin of the loop-type diuretic activity of M17055 (1), several variants (3–9) were designed and synthesized by modifying the quinolinone skeleton, and their diuretic activities were compared with the lead 1 and furosem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::918a564726e8a8a18bb727f02c92a0b4
https://doi.org/10.1002/chin.200031152
https://doi.org/10.1002/chin.200031152
A graph theoretical approach for analysis of protein flexibility change at protein complex formation
Autor:
Carlos A, Del Carpio M, Abdul Rajjak, Shaikh, Eichiro, Ichiishi, Michihisa, Koyama, Momoji, Kubo, Kazumi, Nishijima, Akira, Miyamoto
Publikováno v:
Genome informatics. International Conference on Genome Informatics. 16(2)
Hitherto analyses of protein complexes are frequently confined to the changes in the interface of the protein subunits undergoing interaction, while the holistic picture of the protein monomers' structure transformation, or the pervasive rigidity ado
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80ebe8a1a2bc27f825d37a79dd659a7b
https://pubmed.ncbi.nlm.nih.gov/16901098
https://pubmed.ncbi.nlm.nih.gov/16901098