Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Kazumasa Shimizu"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 136, Iss 1, Pp 26-30 (2018)
Chlorogenic acid (CGA) is a polyphenol found in coffee and medicinal herbs such as Lonicera japonica. In this study, the effect of CGA-induced relaxation on carbachol (CCh)-induced contraction of mouse urinary bladder was investigated. CGA (30–300
Externí odkaz:
https://doaj.org/article/ec6aea9718fb4eaeb06c6701565efd11
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 4, Pp 311-318 (2007)
The mechanism by which ibudilast induces vasodilation was examined in isolated endothelium-denuded rat aorta. Ibudilast inhibited the contractions induced by phenylephrine (PE) and high K+ with decrease of [Ca2+]i level in a concentration-dependent m
Externí odkaz:
https://doaj.org/article/d6aaa64c9e5247eba2053e9e6d5b7171
Autor:
Takeharu Kaneda, Mayumi Takeuchi, Kazumasa Shimizu, Norimoto Urakawa, Shinjiro Nakajyo, Mariko Mochizuki-Kobayashi, Fukiko Ueda, Ryo Hondo
Publikováno v:
Journal of Pharmacological Sciences, Vol 100, Iss 2, Pp 133-141 (2006)
Abstract.: In this study, we examined the inhibitory mechanism of monensin on high K+-induced contraction in guinea-pig urinary bladder. The relaxant effect of monensin (0.001 – 10 µM) was more potent than those of NaCN (100 µM – 1 mM) and fors
Externí odkaz:
https://doaj.org/article/19436369542d46a99c6a0ac1ab9d632b
Autor:
Takeharu Kaneda, Yukako Takeuchi, Hirozumi Matsui, Kazumasa Shimizu, Norimoto Urakawa, Shinjiro Nakajyo
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 3, Pp 275-282 (2005)
We have demonstrated that the relaxing mechanism of papaverine in phasic muscles such as ileum, urinary bladder, and uterus is different from tonic muscles such as aorta. In this study, we examined the inhibitory mechanism of papaverine on carbachol
Externí odkaz:
https://doaj.org/article/9a569b381167459d903e22bf74f39853
Publikováno v:
The Journal of Veterinary Medical Science
Exposure to chronic hypoxic conditions causes various gastric diseases, including gastric ulcers. It has been suggested that gastric smooth muscle contraction is associated with aerobic metabolism. However, there are no reports on the association bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76101176591961eccbe6a67120cb77f8
http://europepmc.org/articles/PMC5989034
http://europepmc.org/articles/PMC5989034
Publikováno v:
The Journal of Veterinary Medical Science
The mechanism of imidazole-induced contraction on the bovine tracheal smooth muscle was investigated. Imidazole induced muscle contraction in a concentration-dependent manner on bovine, porcine and guinea-pig tracheas, but not in rat or mouse. In bov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9756247a1727fb911d4f2e69fca61f
https://doi.org/10.1292/jvms.17-0526
https://doi.org/10.1292/jvms.17-0526
Publikováno v:
Journal of Pharmacological Sciences, Vol 136, Iss 1, Pp 26-30 (2018)
Chlorogenic acid (CGA) is a polyphenol found in coffee and medicinal herbs such as Lonicera japonica. In this study, the effect of CGA-induced relaxation on carbachol (CCh)-induced contraction of mouse urinary bladder was investigated. CGA (30–300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064b166db0ab7f1b9e5f5b76d3d2e4cf
http://www.sciencedirect.com/science/article/pii/S1347861317302098
http://www.sciencedirect.com/science/article/pii/S1347861317302098
Publikováno v:
The Journal of Veterinary Medical Science
The present study was designed to clarify phosphodiesterase 9 (PDE9) expression in bovine tracheal smooth muscle tissue, and to elucidate that PDE9 may contribute to the regulation of airway relaxation. PDE9 mRNA expression was detected in bovine tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6783251d7216b4af5996ea0d5c19e5c8
http://europepmc.org/articles/PMC5880833
http://europepmc.org/articles/PMC5880833
Autor:
Akira Kawaguchi, Kazumasa Shimizu, Takeharu Kaneda, Tsuyoshi Tajima, Hiroetsu Suzuki, Hidenori Kanda, Noriyasu Sasaki, Norimoto Urakawa
Publikováno v:
Journal of Veterinary Medical Science. 79:593-601
Recent studies have shown that phloridzin, an inhibitor of sodium-glucose cotransporter (SGLT), strongly decreases high K+-induced contraction in phasic muscle, such as tenia coli, but slightly affects tonic muscle, such as trachea . In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8586c01ff618442100d8268737d8d4f8
https://doi.org/10.1292/jvms.16-0560
https://doi.org/10.1292/jvms.16-0560
Autor:
Kazumasa Shimizu, Takuya Yogo, Takeharu Kaneda, Asami Kato, Norimoto Urakawa, Yasusi Hara, Hidenori Kanda, Yasuji Harada
Publikováno v:
The Journal of Veterinary Medical Science
Eyes are supplied O2 through the cornea and vessels of the retina and iris, which are tissues characterized by aerobic metabolism. Meanwhile, there are no reports on the association between iris sphincter contraction and aerobic metabolism. In this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0f215c6327027195ef74ed8d9f2568
https://doi.org/10.1292/jvms.16-0175
https://doi.org/10.1292/jvms.16-0175