Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kazumasa Moriwaki"'
Autor:
Kazumasa Moriwaki, Masaki Wada, Hiroko Kuwabara, Yusuke Ayani, Tetsuya Terada, Masaaki Higashino, Ryo Kawata, Michio Asahi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Parotid gland cancer (PGC) is a rare malignancy and its molecular characteristics remain poorly understood, which has precluded the development of effective drug therapies. Given the poor prognosis of many human cancers in which tropomyosin
Externí odkaz:
https://doaj.org/article/890df08b97d6404babd1766b535604d3
Autor:
Mahito Matsuno, Shunichi Yokoe, Takehiro Nagatsuka, Hirofumi Morihara, Kazumasa Moriwaki, Michio Asahi
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
O-GlcNAc transferase (OGT) modulates many functions of proteins via O-GlcNAcylation that adds O-linked β-N-acetylglucosamine (O-GlcNAc) to the serine/threonine residues of proteins. However, the role of O-GlcNAcylation in cardiac remodeling and func
Externí odkaz:
https://doaj.org/article/da8a0d57575f45aaaab0b8210cb8cc44
Autor:
Michio Asahi, Kazumasa Moriwaki
Supplemental Figure 2. Spontaneous apoptosis in tumor tissues does not differ significantly between WT and Ogt-Tg/+ mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a0c9988e69199941c20bf9b696ccb4
https://doi.org/10.1158/1541-7786.22514407
https://doi.org/10.1158/1541-7786.22514407
Publikováno v:
Biochemical and Biophysical Research Communications. 521:632-638
O-GlcNAcylation is a dynamic and reversible post-translational modification of cytonuclear molecules that regulates cellular signaling. Elevated O-GlcNAcylation is a general property of cancer and plays a critical role in cancer progression. We previ
Autor:
Kazumasa Moriwaki, Hirofumi Morihara, Shunichi Yokoe, Kiichiro Tomoda, Michio Asahi, Shigeo Wakabayashi, Takatoshi Nakagawa
Publikováno v:
Journal of Biological Chemistry. 294:19577-19588
Understanding the specific properties of human induced pluripotent stem cells (iPSCs) is important for quality control of iPSCs. Having incidentally discovered that overexpression of plasma membrane Na+/H+ exchanger 1 (NHE1) induces cell death in iPS
Autor:
Takehiro Yamaguchi, Takatoshi Nakagawa, Tetsuya Hayashi, Ryuji Kato, Shunichi Yokoe, Kazumasa Moriwaki, Michio Asahi, Minoru Yoshiyama, Atsuo Nomura, Yoshio Ijiri, Yuichi Furukawa, Yasukatsu Izumi
Publikováno v:
Hypertension Research. 42:1858-1871
Type 2 diabetes mellitus (T2DM) has been reported to be associated with cardiac remodeling. Although O-GlcNAcylation is known to be elevated in diabetic and ischemic hearts, the effects of O-GlcNAcylation on cardiac remodeling induced by intermittent
Autor:
Kazumasa Moriwaki, Hiroko Kuwabara, Yusuke Ayani, Masaaki Higashino, Tetsuya Terada, Ryo Kawata, Michio Asahi
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:3-B
Publikováno v:
Oncotarget
It has been reported that one of the neurotrophin receptors, tropomyosin receptor kinase B (TRKB), is frequently overexpressed in various tumor tissues including oral squamous cell carcinoma (OSCC), and that its upregulation promotes tumor progressio
Publikováno v:
Biochemical and Biophysical Research Communications. 495:904-910
W9 is a peptide that abrogates osteoclast differentiation via blockade of nuclear factor-κB ligand (RANKL)-RANK signaling, which activates bone formation. However, W9 stimulated osteogenesis in osteoblasts and mesenchymal stem cells. The present stu
Autor:
Kazumasa Moriwaki, Michio Asahi
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO1-8