Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kazuma Ohtaka"'
Publikováno v:
European Journal of Breast Health, Vol 18, Iss 2, Pp 195-198 (2022)
Granulomatous mastitis (GM) is a chronic inflammatory disease of the breast that usually occurs in women of reproductive age. However, GM during pregnancy is unusual and only one case of GM in the accessory breast has been reported so far. Here, we r
Externí odkaz:
https://doaj.org/article/de21a00f35774ad7880dc575610c7e7d
Autor:
Takao Ohtsuka, Takao Ide, Kohji Miyazaki, Kazuma Ohtaka, Atsushi Miyoshi, Yoshihiko Kitajima, Mayumi Mitsuno
Publikováno v:
Annals of Surgical Oncology. 14:2600-2607
Pancreatic cancer is one of the representative solid tumors, in which the hypoxic microenvironment plays a crucial role in malignant progression. We previously demonstrated that tumor-stromal interaction under hypoxia enhances the invasiveness of pan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a076275d059d58d0024eb620ce5dce
https://doi.org/10.1245/s10434-007-9435-3
https://doi.org/10.1245/s10434-007-9435-3
Autor:
Yoshihiko Kitajima, Kazuyoshi Hashiguchi, Kazuma Ohtaka, Kohji Miyazaki, Naohiko Kohya, Hirokazu Noshiro, Keita Kai, Masatsugu Hiraki, Osamu Tokunaga, Jun Nakamura
Publikováno v:
International journal of oncology. 37(4)
Gemcitabine is a commonly used chemotherapeutic agent for advanced biliary tract carcinoma (BTC), although its efficacy is insufficient. Therefore, it is essential to establish new diagnostic methods, which can predict responders before the treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0858646688d7eea3160c5ec3f148c4
https://pubmed.ncbi.nlm.nih.gov/20811706
https://pubmed.ncbi.nlm.nih.gov/20811706
Autor:
Mayumi, Mitsuno, Yoshihiko, Kitajima, Kazuma, Ohtaka, Keita, Kai, Kazuyoshi, Hashiguchi, Jun, Nakamura, Masatsugu, Hiraki, Hirokazu, Noshiro, Kohji, Miyazaki
Publikováno v:
International journal of oncology. 36(2)
Gemcitabine (Gem) is a dFdC analogue with activity against several solid tumors. Gem is intracellularly phosphorylated by dCK, leading to the production of the metabolite dFdCDP. dFdCDP exhibits the cytotoxic effect by inactivating ribonucleotide red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82bc9a943a311fb9dfcebd2747278976
https://pubmed.ncbi.nlm.nih.gov/20043067
https://pubmed.ncbi.nlm.nih.gov/20043067
Autor:
Mayumi Mitsuno, Masatsugu Hiraki, Kazuma Ohtaka, Yoshihiko Kitajima, Keita Kai, Kazuyoshi Hashiguchi, Kohji Miyazaki, Hirokazu Noshiro, Jun Nakamura
Publikováno v:
International Journal of Oncology. 36
Gemcitabine (Gem) is a dFdC analogue with activity against several solid tumors. Gem is intracellularly phosphorylated by dCK, leading to the production of the metabolite dFdCDP. dFdCDP exhibits the cytotoxic effect by inactivating ribonucleotide red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c73a26259017bd2cb6b9bc531318c46e
https://doi.org/10.3892/ijo_00000505
https://doi.org/10.3892/ijo_00000505
Autor:
Naohiko Kohya, Kazuma Ohtaka, Yoshihiko Kitajima, Mayumi Mitsuno, Kohji Miyazaki, Takao Ide, Ken Sato
Publikováno v:
Oncology reports. 20(2)
Biliary tract carcinoma is a relatively rare tumor with a poor prognosis. Surgical resection is the only potential cure. However, the efficacy of chemotherapeutic agents is disappointing in advanced or recurrent cases. Gemcitabine (GEM) appears to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73807ddbf006ec016eaa0195edb12da2
https://pubmed.ncbi.nlm.nih.gov/18636187
https://pubmed.ncbi.nlm.nih.gov/18636187
Publikováno v:
Oncology reports. 19(6)
The loss of a DNA mismatch repair occurs in approximately 15% of sporadic colorectal cancer (CRC) and is usually caused by the lack of expression of the hMLH1 gene due to promoter methylation. Despite undergoing adjuvant 5-fluorouracil (5-FU) therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e1cb408e5394062c089bcbec333168
https://pubmed.ncbi.nlm.nih.gov/18497967
https://pubmed.ncbi.nlm.nih.gov/18497967
Autor:
Kohji Miyazaki, Kazuma Ohtaka, Yoshihiko Kitajima, Yuji Nakafusa, Seiji Sato, Masayuki Tanaka, Mayumi Mitsuno
Publikováno v:
Oncology reports. 19(1)
Runx3, a member of the human runt-related transcription factor family, is known as a possible tumor suppressor gene for gastric cancer. Runx 3 expression is frequently suppressed by the promoter hypermethylation in gastric cancer cell lines and tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddf06d6693ab4dc63bf6e4d648c43ad
https://pubmed.ncbi.nlm.nih.gov/18097595
https://pubmed.ncbi.nlm.nih.gov/18097595
Autor:
Masayuki Tanaka, Kohji Miyazaki, Kazuma Ohtaka, Mayumi Mitsuno, Seiji Satoh, Yoshihiko Kitajima, Takao Ide
Publikováno v:
Journal of gastroenterology. 42(11)
Aberrant methylation of some cancer-related genes has been reported to correlate with sensitivity to chemotherapeutic agents. The present study was designed to determine whether DNA methylation in six cancer-related genes affects recurrence of gastri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32d7bc0359d65cb7488dfc6d619dcd5
https://pubmed.ncbi.nlm.nih.gov/18008030
https://pubmed.ncbi.nlm.nih.gov/18008030
Publikováno v:
Anticancer research. 27(2)
Biliary tract cancer is of highly malignancy with a poor 5-year survival. However, established chemotherapeutic regimens have not yet been established. Previously, we have reported that hMLH1, a mismatch repair (MMR) gene was frequently (57%) found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04e73248f051e5f3852422d72c838dd4
https://pubmed.ncbi.nlm.nih.gov/17465213
https://pubmed.ncbi.nlm.nih.gov/17465213