Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Kazuma Mawatari"'
Autor:
Ai Kuzumi, Ayumi Yoshizaki, Kazuki M. Matsuda, Hirohito Kotani, Yuta Norimatsu, Maiko Fukayama, Satoshi Ebata, Takemichi Fukasawa, Asako Yoshizaki-Ogawa, Yoshihide Asano, Kyojiro Morikawa, Yutaka Kazoe, Kazuma Mawatari, Takehiko Kitamori, Shinichi Sato
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Systemic sclerosis (SSc) disease involves multisystem fibrosis and autoimmunity with limited treatment options. Here the authors demonstrate that IL-31 and IL-31RA are overexpressed in dermal fibroblasts from SSc patients and show that fibrosis and c
Externí odkaz:
https://doaj.org/article/77ed6d1edb6547f483a763bb26f767ba
Autor:
Takemichi Fukasawa, Ayumi Yoshizaki, Satoshi Ebata, Asako Yoshizaki-Ogawa, Yoshihide Asano, Atsushi Enomoto, Kiyoshi Miyagawa, Yutaka Kazoe, Kazuma Mawatari, Takehiko Kitamori, Shinichi Sato
Publikováno v:
eLife, Vol 10 (2021)
Despite antigen affinity of B cells varying from cell to cell, functional analyses of antigen-reactive B cells on individual B cells are missing due to technical difficulties. Especially in the field of autoimmune diseases, promising pathogenic B cel
Externí odkaz:
https://doaj.org/article/41969bc1d4ab4eb0b5535a40e0a4f551
Publikováno v:
Micromachines, Vol 12, Iss 8, p 917 (2021)
In microfluidics, especially in nanofluidics, nanochannels with functionalized surfaces have recently attracted attention for use as a new tool for the investigation of chemical reaction fields. Molecules handled in the reaction field can reach the s
Externí odkaz:
https://doaj.org/article/cc42c2e82a4c4e2baf150bb70cdea72f
Publikováno v:
Micromachines, Vol 9, Iss 9, p 423 (2018)
Micro liquid droplets and plugs in the gas-phase in microchannels have been utilized in microfluidics for chemical analysis and synthesis. While higher velocities of droplets and plugs are expected to enable chemical processing at higher efficiency a
Externí odkaz:
https://doaj.org/article/7e55899c8bec4c7b99fbc6b3b013aaa2
Publikováno v:
Micromachines, Vol 7, Iss 8, p 142 (2016)
Microfluidics has been used to perform various chemical operations for pL–nL volumes of samples, such as mixing, reaction and separation, by exploiting diffusion, viscous forces, and surface tension, which are dominant in spaces with dimensions on
Externí odkaz:
https://doaj.org/article/80b3759387384dcb89664456e2833302
Autor:
Takehiko Kitamori, Kazuma Mawatari, Takehiko Tsukahara, Yo Tanaka, Yutaka Kazoe, Philip Dextras
For the past decade, new research fields utilizing microfluidics have been formed. General micro-integration methods were proposed, and the supporting fundamental technologies were widely developed. These methodologies have made various applications
Autor:
Yutaka Kazoe, Keisuke Ikeda, Kensuke Mino, Kyojiro Morikawa, Kazuma Mawatari, Takehiko Kitamori
Publikováno v:
Analytical Sciences. 39:779-784
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f0ed6836990fbb1e34494b93434b2a2
https://doi.org/10.1007/s44211-023-00311-x
https://doi.org/10.1007/s44211-023-00311-x
Publikováno v:
Analytical Sciences. 38:281-287
With developments in analytical devices promoted by nanofluidics, estimation of the flow rate in a nanochannel has become important to calculate volumes of samples and reagents in chemical processing. However, measurement of the flow rate in nanospac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa52bc8a78589d33e2fef064e15fc266
https://doi.org/10.2116/analsci.21p198
https://doi.org/10.2116/analsci.21p198
Autor:
Kyojiro Morikawa, Kazuki M. Matsuda, Ayumi Yoshizaki, Takehiko Kitamori, Ai Kuzumi, Yuta Norimatsu, Maiko Fukayama, Yutaka Kazoe, Asako Yoshizaki-Ogawa, Yoshihide Asano, Takemichi Fukasawa, Shinichi Sato, Hirohito Kotani, Kazuma Mawatari, Satoshi Ebata
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Systemic sclerosis (SSc) is a chronic multisystem disorder characterized by fibrosis and autoimmunity. Interleukin (IL)-31 has been implicated in fibrosis and T helper (Th) 2 immune responses, both of which are characteristics of SSc. The exact role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35593531e593c6af4e9e3a104fd98324
https://doaj.org/article/77ed6d1edb6547f483a763bb26f767ba
https://doaj.org/article/77ed6d1edb6547f483a763bb26f767ba
Autor:
Satoshi Ebata, Takehiko Kitamori, Yutaka Kazoe, Ai Kuzumi, Ayumi Yoshizaki, Yoshihide Asano, Takemichi Fukasawa, Kazuma Mawatari, Hiroko Numajiri, Shinichi Sato, Asako Yoshizaki-Ogawa
Publikováno v:
Arthritis & Rheumatology. 73:2086-2095
OBJECTIVE We undertook this study to investigate the effect of B cell depletion on fibrosis in systemic sclerosis (SSc) and its mechanism of action. METHODS Mice with bleomycin-induced SSc (BLM-SSc) were treated with anti-CD20 antibody, and skin and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b549089a3dde8ed366e5c53fd4392511
https://doi.org/10.1002/art.41798
https://doi.org/10.1002/art.41798