Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Kazuko Shibuya"'
Autor:
Yuki Goshima, Shinji Nakaoka, Kazuteru Ohashi, Hisashi Sakamaki, Kazuko Shibuya, Akira Shibuya
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228508 (2020)
DNAM-1 (CD226) is an activating immunoreceptor expressed on T cells and NK cells and involved in the pathogenesis of acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). We previously reported
Externí odkaz:
https://doaj.org/article/c3348a7986b3477db36e3905dff292d5
Selective DNAM-1 expression on small peritoneal macrophages contributes to CD4+ T cell costimulation
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Mouse peritoneal macrophages consist of two subsets: large peritoneal macrophages (LPMs) and small peritoneal macrophages (SPMs), defined as CD11bhiF4/80hi and CD11b+F4/80lo cells, respectively. We reveal that SPMs, but not LPMs, have the ab
Externí odkaz:
https://doaj.org/article/8c34dccbeeeb4050956e420ac25b6467
Autor:
Shin-ichiro Honda, Kazuki Sato, Naoya Totsuka, Satoshi Fujiyama, Manabu Fujimoto, Kensuke Miyake, Chigusa Nakahashi-Oda, Satoko Tahara-Hanaoka, Kazuko Shibuya, Akira Shibuya
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Marginal zone B cells are mostly characterized in the context of host defense against bacterial blood-borne pathogens. Here the authors show that TLR4 signaling in these cells requires Fcα/μR (CD351) and that they are a major source of IL-6 in a mo
Externí odkaz:
https://doaj.org/article/56c8baf3ce2c4f159fbd3742c478ed1d
Autor:
Minoru Kanaya, Kazuko Shibuya, Rei Hirochika, Miyoko Kanemoto, Kazuteru Ohashi, Masafumi Okada, Yukiko Wagatsuma, Yukiko Cho, Hiroshi Kojima, Takanori Teshima, Masahiro Imamura, Hisashi Sakamaki, Akira Shibuya
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0154173 (2016)
Acute graft-versus-host disease (aGVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Because diagnosis of aGVHD is exclusively based on clinical symptoms and pathological findings, reliable and noninvasiv
Externí odkaz:
https://doaj.org/article/da27857650174173b3b5f05bddf893b3
Autor:
Akiko Iguchi-Manaka, Genki Okumura, Hiroshi Kojima, Yukiko Cho, Rei Hirochika, Hiroko Bando, Toyomi Sato, Hiroyuki Yoshikawa, Hisato Hara, Akira Shibuya, Kazuko Shibuya
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152982 (2016)
Emerging evidence suggests that DNAM-1 (CD226) play an important role in the recognition of tumor cells and their lysis by cytotoxic T lymphocytes (CTL) and NK cells. Although the DNAM-1 ligand CD155 is ubiquitously expressed in various tissues, many
Externí odkaz:
https://doaj.org/article/47dac93118794e0d9aa7443efd86b222
Autor:
Yoko Nagumo, Akiko Iguchi-Manaka, Yumi Yamashita-Kanemaru, Fumie Abe, Günter Bernhardt, Akira Shibuya, Kazuko Shibuya
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112415 (2014)
Tumor recognition by immune effector cells is mediated by antigen receptors and a variety of adhesion and costimulatory molecules. The evidence accumulated since the identification of CD155 and CD112 as ligands for DNAM-1 in humans and mice has sugge
Externí odkaz:
https://doaj.org/article/cfda1dca4e3c4101a8c55b98b858da2f
Autor:
Rikito Murata, Shota Kinoshita, Kenshiro Matsuda, Atsushi Kawaguchi, Akira Shibuya, Kazuko Shibuya
Publikováno v:
The Journal of Immunology. 209:2304-2312
Although rs763361, which causes a nonsynonymous glycine-to-serine mutation at residue 307 (G307S mutation) of the DNAX accessory molecule-1 (DNAM-1) immunoreceptor, is a single-nucleotide polymorphism associated with autoimmune disease susceptibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6936890f45000f04e154d78a994304
https://doi.org/10.4049/jimmunol.2200608
https://doi.org/10.4049/jimmunol.2200608
Publikováno v:
Journal of immunology. 209(12):2313-2321
Psoriasis is a chronic inflammatory skin disease. IL-23 plays a critical role in its pathogenesis by inducing production of IL-17A from pathological Th17 cells and IL-17A–producing γδ T cells. However, the mechanisms regulating the IL-23/IL-17 ax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8314b22f9a248705750ed3077c1f5fd6
https://tsukuba.repo.nii.ac.jp/records/2007069
https://tsukuba.repo.nii.ac.jp/records/2007069
Autor:
Toshiki Yamada, Megumi Tatematsu, Shunsuke Takasuga, Akane Fuchimukai, Kenki Yamagata, Shinsuke Seki, Keiji Kuba, Hideyuki Yoshida, Ichiro Taniuchi, Günter Bernhardt, Kazuko Shibuya, Akira Shibuya, Takechiyo Yamada, Takashi Ebihara
Publikováno v:
Journal of Experimental Medicine. 220
While group-2 innate lymphoid cells (ILC2s) are highly proliferative in allergic inflammation, the removal of overactivated ILC2s in allergic diseases has not been investigated. We previously showed that chronic airway allergy induces “exhausted-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c29f3e88c9eaba9613fdae4b2a0c377f
https://doi.org/10.1084/jem.20222005
https://doi.org/10.1084/jem.20222005
Autor:
Kazuko Shibuya, Akira Shibuya
Publikováno v:
International Immunology. 33:687-692
The co-stimulatory and co-inhibitory immunoreceptors, DNAX accessory molecule-1 (DNAM-1) and T-cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibitory motif (ITIM) domain (TIGIT), are paired activating and inhibitory rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8758830d14d8de14f1ab7929bc6ac2d6
https://doi.org/10.1093/intimm/dxab085
https://doi.org/10.1093/intimm/dxab085