Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Kazuko Ogawa"'
Autor:
Naoyuki Taniguchi, Kazuko Ogawa, Soichi Kojima, Koichi Honke, Rie Imamaki, Yusuke Komi, Takashi Honda, Yasuhiko Kizuka, Shinobu Kitazume, Norihiro Kotani
Publikováno v:
Oncogene. 37(31)
Most of the angiogenesis inhibitors clinically used in cancer treatment target the vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) pathway. However, the current strategies for treating angiogenesis have limited efficacy. The issue of
Autor:
Naoki Tomita, Shinobu Kitazume, Nobuhisa Iwata, Takaomi C. Saido, Yasuchika Takeishi, Naoyuki Taniguchi, Akiomi Yoshihisa, Yoshiaki Hagiwara, Masayoshi Oikawa, Naomasa Yamamoto, Takayoshi Yamaki, Yuriko Tachida, Katsutoshi Furukawa, Rie Imamaki, Kazuko Ogawa, Hiroyuki Arai, Noriaki Kinoshita
Publikováno v:
Journal of Biological Chemistry. 287:40817-40825
Most Alzheimer disease (AD) patients show deposition of amyloid β (Aβ) peptide in blood vessels as well as the brain parenchyma. We previously found that vascular endothelial cells express amyloid β precursor protein (APP) 770, a different APP iso
Autor:
Ritsuko Oka, Eiji Miyoshi, Michio Kato, Akinori Kasahara, Naoyuki Taniguchi, Yoshiaki Hagiwara, Satoshi Futakawa, Yasuhiro Hashimoto, Shinobu Kitazume, Hajime Takikawa, Kazuko Ogawa
Publikováno v:
Glycobiology. 19:479-487
Beta-galactoside alpha2,6-sialyltransferase (ST6Gal I), which is highly expressed in the liver, is mainly cleaved by Alzheimer's beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1) and secreted into the serum. During our studies to elucidat
Autor:
Yasuhiro Hashimoto, Kazuko Ogawa, Satoshi Futakawa, Yoshiaki Hagiwara, Ritsuko Oka, Akinori Kinoshita, Shinobu Kitazume, Kazuya Miyashita
Publikováno v:
Analytica Chimica Acta. 631:116-120
Previous reports, including our work, have shown that plasma beta-galactoside alpha2,6-sialyltransferase (ST6Gal I) activity is significantly increased in particular hepatopathological situations, suggesting that it may represent a sensitive biomarke
Autor:
Ritsuko Oka, Yasuhiro Hashimoto, Ichiro Sugimoto, Satoshi Futakawa, Naoyuki Taniguchi, Jamey D. Marth, Eiji Miyoshi, Shinobu Kitazume, Kazuko Ogawa
Publikováno v:
Journal of Biological Chemistry. 282:34896-34903
BACE1 (β-site amyloid precursor protein-cleaving enzyme-1) is a membrane-bound aspartic protease that cleaves amyloid precursor protein to produce a neurotoxic peptide, amyloid β-peptide, and has been implicated in triggering the pathogenesis of Al
Autor:
Naoshi Dohmae, Kazuko Ogawa, Yasuhiro Hashimoto, Takaomi C. Saido, Yuriko Tachida, Norihiro Kotani, Shinobu Kitazume, Koji Takio, Ritsuko Oka, Minoru Suzuki
Publikováno v:
Journal of Biological Chemistry. 278:14865-14871
BACE1 is a membrane-bound aspartic protease that cleaves the amyloid precursor protein (APP) at the beta-secretase site, a critical step in the Alzheimer disease pathogenesis. We previously found that BACE1 also cleaved a membrane-bound sialyltransfe
Publikováno v:
Genes to Cells. 7:629-638
Background: We have shown recently that read-through of a normal stop codon by a suppressor tRNA in specific genes possessing a Rho-independent terminator leads to SsrA-mediated tagging of extended proteins in Escherichia coli cells. Miscoding antibi
Publikováno v:
Genes to Cells. 7:509-519
Backgrounds: Bacterial SsrA RNA (also known as tmRNA or 10Sa RNA) mediates the addition of a short peptide tag to the C-terminus of the nascent polypeptide when a ribosome is stalled at the 3′ end of an mRNA lacking a stop codon. This process, call
Autor:
Ayako Kurimoto, Katsunori Tanaka, Rie Imamaki, Yoshiki Yamaguchi, Hiromune Ando, Kazuko Ogawa, Naoyuki Taniguchi, Makoto Kiso, Hideharu Ishida, Nana Kawasaki, Masaki Kato, Noritaka Hashii, Shinobu Kitazume
Publikováno v:
The Journal of biological chemistry. 289(40)
The luminal sides of vascular endothelial cells are heavily covered with a so-called glycocalyx, but the precise role of the endothelial glycocalyx remains unclear. Our previous study showed that N-glycan α2,6-sialylation regulates the cell surface
Publikováno v:
The EMBO Journal. 19:3762-3769
SsrA RNA of Escherichia coli , also known as 10Sa RNA or tmRNA, acts both as tRNA and mRNA when ribosomes are paused at the 3′ end of an mRNA lacking a stop codon. This process, referred to as trans ‐translation, leads to the addition of a short