Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kazuko Miyazaki"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune responses are primarily mediated by adaptive and innate immune cells. Adaptive immune cells, such as T and B cells, evoke antigen-specific responses through the recognition of specific antigens. This antigen-specific recognition relies on the
Externí odkaz:
https://doaj.org/article/d3add3a6647c4f6b81bcf1cb1f9967e8
Autor:
Kazuko Miyazaki, Seung Chik Jwa, Eri Katayama, Shunsuke Tamaru, Osamu Ishihara, Yoshimasa Kamei
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Surgical site infection (SSI) is a common but potentially serious maternal complication of cesarean section (CS). C-reactive protein (CRP) can be used in early detection of SSI. However, its predictive value for post-cesarean SSI has never been inves
Externí odkaz:
https://doaj.org/article/62b9e690dad144469db2be5680ed942d
Autor:
Kazuko Miyazaki, Masaki Miyazaki
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cell type-specific gene expression is driven through the interplay between lineage-specific transcription factors (TFs) and the chromatin architecture, such as topologically associating domains (TADs), and enhancer-promoter interactions. To elucidate
Externí odkaz:
https://doaj.org/article/113cf3f22a134c7f8cb5dc3ec38221b7
Autor:
Masaki Miyazaki, Kazuko Miyazaki
Publikováno v:
Journal of biochemistry. 172(5)
Our bodies are constantly threatened with the invasion of pathogens, such as bacteria and virus. Immune responses against pathogens are evoked in collaboration with adaptive and innate immune systems. Adaptive immune cells including T and B cells rec
Autor:
Gen Kondoh, Yotaro Ochi, Masaki Miyazaki, Kai Osawa, Osamu Takeuchi, Reiko Hidaka, Kazuko Miyazaki, Shizue Tani-ichi, Hitomi Watanabe, Rie Takeda, Hiroyuki Ogata, Kenian Chen, Genki Yoshikawa, Takuya Uehata, Koichi Ikuta, Yin C. Lin, Yuki Aitani, Seishi Ogawa
Publikováno v:
Science Immunology. 5
Cell type-specific gene expression is driven by the interplay between lineage-specific transcription factors and cis-regulatory elements to which they bind. Adaptive immunity relies on RAG-mediated assembly of T cell receptor (TCR) and immunoglobulin
Autor:
Kazuko, Miyazaki, Hitomi, Watanabe, Genki, Yoshikawa, Kenian, Chen, Reiko, Hidaka, Yuki, Aitani, Kai, Osawa, Rie, Takeda, Yotaro, Ochi, Shizue, Tani-Ichi, Takuya, Uehata, Osamu, Takeuchi, Koichi, Ikuta, Seishi, Ogawa, Gen, Kondoh, Yin C, Lin, Hiroyuki, Ogata, Masaki, Miyazaki
Publikováno v:
Science immunology. 5(51)
Cell type-specific gene expression is driven by the interplay between lineage-specific transcription factors and cis-regulatory elements to which they bind. Adaptive immunity relies on RAG-mediated assembly of T cell receptor (
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5888, p 5888 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 5888, p 5888 (2021)
Adaptive immunity relies on the V(D)J DNA recombination of immunoglobulin (Ig) and T cell receptor (TCR) genes, which enables the recognition of highly diverse antigens and the elicitation of antigen-specific immune responses. This process is mediate
Autor:
Kazuko Miyazaki, Susumu Kageyama, Akihiro Kawauchi, Masayuki Nagasawa, Koji Terada, Yasutoshi Agata, Hiroshi Kawamoto, Masaki Miyazaki, Daisuke Okuzaki, Kenta Kondo, Kosuke Tomimatsu, Daisuke Motooka, Tetsuya Yoshida
Publikováno v:
Biochemical and biophysical research communications. :S0006
Androgen receptor (AR)-negative castration-resistant prostate cancer (CRPC) is highly aggressive and is resistant to most of the current therapies. Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive hig
Autor:
Shuwen Chen, Hans Reimer Rodewald, Rintaro Saito, Hiroshi Kawamoto, Keisuke Wagatsuma, Yasutoshi Agata, Aaron N. Chang, Nissi Varki, Kazuko Miyazaki, Masaki Miyazaki, Cornelis Murre, Vivek Chandra
Publikováno v:
Genes & Development. 29:409-425
It is now well established that the E and Id protein axis regulates multiple steps in lymphocyte development. However, it remains unknown how E and Id proteins mechanistically enforce and maintain the naïve T-cell fate. Here we show that Id2 and Id3
Publikováno v:
Trends in Immunology. 35:205-210
In B cell progenitors, E-proteins E2A and HEB (HeLa E-box binding protein) are crucial for the induction of a B lineage-specific program of gene expression and for orchestrating the assembly of the immunoglobulin loci. In the thymus E2A and HEB act d