Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kazuki Teranishi"'
Autor:
Kazuki Teranishi, Keisuke Wagatsuma, Keisuke Toda, Hiroko Nomaru, Yuichi Yanagihashi, Hiroshi Ochiai, Satoru Akai, Emi Mochizuki, Yuuki Onda, Keiji Nakagawa, Keiki Sugimoto, Shinya Takahashi, Hideto Yamaguchi, Sadao Ota
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Automation and quality control (QC) are critical in manufacturing safe and effective cell and gene therapy products. However, current QC methods, reliant on molecular staining, pose difficulty in in-line testing and can increase manufacturin
Externí odkaz:
https://doaj.org/article/f3710d244fd24222be4aa7e3d538e246
Autor:
Alan K. Okada, Kazuki Teranishi, Mark R. Ambroso, Jose Mario Isas, Elena Vazquez-Sarandeses, Joo-Yeun Lee, Arthur Alves Melo, Priyatama Pandey, Daniel Merken, Leona Berndt, Michael Lammers, Oliver Daumke, Karen Chang, Ian S. Haworth, Ralf Langen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely unexplored whether lysine acetylation regulates the function of membrane proteins. Here, the authors map lysine acetylation predominantly in membrane-intera
Externí odkaz:
https://doaj.org/article/969a6247f4f548d799fa269799855a27
Autor:
J. Mario Isas, Nitin K. Pandey, Hui Xu, Kazuki Teranishi, Alan K. Okada, Ellisa K. Fultz, Anoop Rawat, Anise Applebaum, Franziska Meier, Jeannie Chen, Ralf Langen, Ansgar B. Siemer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Huntingtin exon-1 (HTTex1) consists of a N-terminal N17 domain, the disease causing polyQ domain and a C-terminal proline-rich domain (PRD). Here, the authors combine electron paramagnetic resonance (EPR), solid-state NMR with other biophysical metho
Externí odkaz:
https://doaj.org/article/a3ad6629dcdc4912b80f4ba73af97d8a
Autor:
Masashi Ugawa, Yoko Kawamura, Keisuke Toda, Kazuki Teranishi, Hikari Morita, Hiroaki Adachi, Ryo Tamoto, Hiroko Nomaru, Keiji Nakagawa, Keiki Sugimoto, Evgeniia Borisova, Yuri An, Yusuke Konishi, Seiichiro Tabata, Soji Morishita, Misa Imai, Tomoiku Takaku, Marito Araki, Norio Komatsu, Yohei Hayashi, Issei Sato, Ryoichi Horisaki, Hiroyuki Noji, Sadao Ota
Publikováno v:
eLife, Vol 10 (2021)
Characterization and isolation of a large population of cells are indispensable procedures in biological sciences. Flow cytometry is one of the standards that offers a method to characterize and isolate cells at high throughput. When performing flow
Externí odkaz:
https://doaj.org/article/f18702ec41bd4ff3a24213c793f591a3
Autor:
Alan K. Okada, Kazuki Teranishi, Fleur Lobo, J. Mario Isas, Jialin Xiao, Kelvin Yen, Pinchas Cohen, Ralf Langen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Mitochondrial-derived peptides (MDPs) and their analogs have emerged as wide-spectrum, stress response factors protective in amyloid disease models. MDP cytoprotective functions are generally attributed to anti-apoptotic activity, however, l
Externí odkaz:
https://doaj.org/article/0f99bdda07fa499097deb4fdc1230f9a
Autor:
Yoko Kawamura, Kayoko Nakanishi, Yuri Murata, Kazuki Teranishi, Ryusuke Miyazaki, Keisuke Toda, Toru Imai, Yasuhiro Kajiwara, Keiji Nakagawa, Hidemasa Matsuo, Souichi Adachi, Sadao Ota, Hidefumi Hiramatsu
Publikováno v:
Cytometry. Part A; Mar2024, Vol. 105 Issue 3, p196-202, 7p
Autor:
Asako Tsubouchi, Yuri An, Yoko Kawamura, Yuichi Yanagihashi, Yuri Murata, Kazuki Teranishi, Soh Ishiguro, Hiroyuki Aburatani, Nozomu Yachie, Sadao Ota
Fast enrichment of cells based on morphological information remains a challenge, limiting genome-wide perturbation screening for diverse high-content phenotypes of cells. Here we show that multi-modal ghost cytometry-based cell sorting is applicable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be4d7f8722597c907d34bf0a57baaed5
https://doi.org/10.1101/2023.01.26.525784
https://doi.org/10.1101/2023.01.26.525784
Autor:
Leona Berndt, Elena Vazquez-Sarandeses, Arthur Alves de Melo, Kazuki Teranishi, Ralf Langen, Mark R. Ambroso, Michael Lammers, Daniel Merken, Oliver Daumke, Ian S. Haworth, Joo-Yeun Lee, Alan K Okada, Jose Mario Isas, Karen Chang, Priyatama Pandey
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely unexplored whether lysine acetylation regulates membrane protein function. Here, we use bioinformatics, biophysical analysis of recombinant proteins, live-c
Autor:
Yoko Kawamura, Masashi Ugawa, Keisuke Toda, Kazuki Teranishi, Hikari Morita, Hiroaki Adachi, Ryo Tamoto, Hiroko Nomaru, Keiji Nakagawa, Keiki Sugimoto, Evgeniia Borisova, Yuri An, Yusuke Konishi, Seiichiro Tabata, Soji Morishita, Misa Imai, Tomoiku Takaku, Marito Araki, Norio Komatsu, Yohei Hayashi, Issei Sato, Ryoichi Horisaki, Hiroyuki Noji, Sadao Ota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24ad30b3821534854109f9d7880b71b5
https://doi.org/10.7554/elife.67660.sa2
https://doi.org/10.7554/elife.67660.sa2
Publikováno v:
Journal of the American Chemical Society. 141:14168-14179
Mitochondrially derived peptides (MDPs) such as humanin (HN) have shown a remarkable ability to modulate neurological amyloids and apoptosis-associated proteins in cells and animal models. Recently, we found that humanin-like peptides also inhibit am