Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kazuki Shimane"'
Autor:
Shingo Mizunaga, Takefumi Hara, Shinji Hagiwara, Tanaka Yasuhito, Kazuki Shimane, Kawano Takaki, Nozomi Nakajima, Toshiyuki Nakatani, Haba Ryota
Publikováno v:
Journal of Hepatology. 70:e465-e466
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4769c8ec5a1626bce156d97aab0454
https://doi.org/10.1016/s0618-8278(19)30919-3
https://doi.org/10.1016/s0618-8278(19)30919-3
Autor:
Masao Matsuoka, Atsuko Hachiya, Eiichi Kodama, Stefan G. Sarafianos, Masafumi Takiguchi, Shinichi Oka, Kazuki Shimane, Hiroyuki Gatanaga, Fujie Negishi, Hirokazu Koizumi, Yasuko Sakagami
Publikováno v:
Antiviral Research. 82:115-121
Some mutations in the connection subdomain of the polymerase domain and in the RNase H domain of HIV-1 reverse transcriptase (RT) have been shown to contribute to resistance to RT inhibitors. However, the clinical relevance of such mutations is not w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83c24405ea9ad7553b963ea4d7e1bec
https://doi.org/10.1016/j.antiviral.2009.02.189
https://doi.org/10.1016/j.antiviral.2009.02.189
Autor:
Kentaro Watanabe, Kazuya Shimura, Yasuko Sakagami, Mitsuo Kaku, Fusako Miyamoto, Kazuki Shimane, Nobutaka Fujii, Stefan G. Sarafianos, Shinya Oishi, Kumi Kawaji, Eiichi Kodama, Masao Matsuoka
Publikováno v:
Antimicrobial agents and chemotherapy. 57(8)
T-20EK is a novel fusion inhibitor designed to have enhanced α-helicity over T-20 (enfuvirtide) through engineered electrostatic interactions between glutamic acid (E) and lysine (K) substitutions. T-20EK efficiently suppresses wild-type and T-20-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80778b673ee5d5eed18d6fb48c480640
https://pubmed.ncbi.nlm.nih.gov/23689710
https://pubmed.ncbi.nlm.nih.gov/23689710
Autor:
Mitsuo Kaku, Kazuki Shimane, Eiichi Kodama, Masao Matsuoka, Kumi Kawaji, Stefan G. Sarafianos, Kazuki Izumi, Shinya Oishi, Fusasko Miyamoto, Kazuya Shimura, Nobutaka Fujii, Toshio Hattori, Yasuko Sakagami, Kentaro Watanabe
T-20 (enfuvirtide) resistance is caused by the N43D primary resistance mutation at its presumed binding site at the N-terminal heptad repeat (N-HR) of gp41, accompanied by the S138A secondary mutation at the C-terminal HR of gp41 (C-HR). We have disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a01bedf3e9f3e4b6156b572040f1a3
https://europepmc.org/articles/PMC4136414/
https://europepmc.org/articles/PMC4136414/
Autor:
Ikuhiko Nakase, Kazuki Shimane, Toshio Hattori, Yasuteru Sakurai, Masao Matsuoka, Yasuko Sakagami, Eiichi Kodama, Shiroh Futaki, Stefan G. Sarafianos, Xiaoguang Li
Publikováno v:
The international journal of biochemistrycell biology. 42(9)
Rev, a viral regulatory protein of HIV-1, binds through its arginine-rich domain to the Rev-responsive element (RRE), a secondary structure in transcribed HIV-1 RNA. Binding of Rev to RRE mediates export of singly spliced or unspliced mRNAs from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4336653793b7736c2d90c972e381a681
https://pubmed.ncbi.nlm.nih.gov/20580677
https://pubmed.ncbi.nlm.nih.gov/20580677
Autor:
Shinya Oishi, Nobutaka Fujii, Tadafumi S. Tochikura, Hajime Tsujimoto, Masao Matsuoka, Hiroki Nishikawa, Fuminori Mizukoshi, Kazuki Shimane, Yasuyo Kodera, Eiichi Kodama, Hirotaka Kamitani, Hiroaki Ohno, Tsuyoshi Watabe
Publikováno v:
Bioorganicmedicinal chemistry. 17(14)
Feline immunodeficiency virus (FIV) is a pathogenic virus that causes an AIDS-like syndrome in the domestic cats. For viral entry and infection, fusion between the virus and the cell membrane is the critical process and this process is mediated by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155a30d92f1829b30afd3882fc3333ed
https://pubmed.ncbi.nlm.nih.gov/19541488
https://pubmed.ncbi.nlm.nih.gov/19541488