Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kazuki Okuyama"'
Autor:
Kazuaki Matsumoto, Kazuki Okuyama, Tom Sidwell, Motoi Yamashita, Takaho Endo, Naoko Satoh-Takayama, Hiroshi Ohno, Tomohiro Morio, Ellen V. Rothenberg, Ichiro Taniuchi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BCL11B is a transcription factor with six C2H2-type zinc-finger domains. Studies in mice have shown that Bcl11b plays essential roles in T cell development. Several germline heterozygous BCL11B variants have been identified in human patients with inb
Externí odkaz:
https://doaj.org/article/83c8db04a2b14d88adbf03ead9999ff0
Autor:
Josefine Åhsberg, Pingnan Xiao, Kazuki Okuyama, Rajesh Somasundaram, Tobias Strid, Hong Qian, Mikael Sigvardsson
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/6844f3330f55450b93fd93d849186633
Autor:
Elisa Crisci, Cecilia Svanberg, Rada Ellegård, Mohammad Khalid, Julia Hellblom, Kazuki Okuyama, Pradyot Bhattacharya, Sofia Nyström, Esaki M. Shankar, Kristina Eriksson, Marie Larsson
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Genital herpes is a common sexually transmitted infection caused by herpes simplex virus type 2 (HSV-2). Genital herpes significantly enhances the acquisition and transmission of HIV-1 by creating a microenvironment that supports HIV infection in the
Externí odkaz:
https://doaj.org/article/b704319f49074632a7daba1f6aa7715a
Autor:
Kazuki Okuyama, Tobias Strid, Jacob Kuruvilla, Rajesh Somasundaram, Susana Cristobal, Emma Smith, Mahadesh Prasad, Thoas Fioretos, Henrik Lilljebjörn, Shamit Soneji, Stefan Lang, Jonas Ungerbäck, Mikael Sigvardsson
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008280 (2019)
One of the most frequently mutated proteins in human B-lineage leukemia is the transcription factor PAX5. These mutations often result in partial rather than complete loss of function of the transcription factor. While the functional dose of PAX5 has
Externí odkaz:
https://doaj.org/article/5fcac02b5c7e4662a7aaef4e9b59c486
Autor:
Akihiko Murata, Miya Yoshino, Mari Hikosaka, Kazuki Okuyama, Lan Zhou, Seiji Sakano, Hideo Yagita, Shin-Ichi Hayashi
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108535 (2014)
Notch family members were first identified as cell adhesion molecules by cell aggregation assays in Drosophila studies. However, they are generally recognized as signaling molecules, and it was unclear if their adhesion function was restricted to Dro
Externí odkaz:
https://doaj.org/article/bf2a0d7dc70c429794fb611410d4672f
Autor:
Metwally, Hozaifa, Elbrashy, Maha M., Tatsuhiko Ozawa, Kazuki Okuyama, White, Jason T., Janyerkye Tulyeu, Søndergaard, Jonas Nørskov, Wing, James Badger, Muratsu, Arisa, Hisatake Matsumoto, Masahito Ikawa, Hiroyuki Kishi, Ichiro Taniuchi, Tadamitsu Kishimoto
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 4/23/2024, Vol. 121 Issue 17, p1-12, 39p
Autor:
Kazuaki Matsumoto, Kazuki Okuyama, Sidwell, Tom, Motoi Yamashita, Takaho Endo, Naoko Satoh-Takayama, Hiroshi Ohno, Tomohiro Morio, Rothenberg, Ellen V., Ichiro Taniuchi
Publikováno v:
Frontiers in Immunology; 2024, p1-14, 14p
Autor:
Kazuki Okuyama, Aneela Nomura, Kohei Nishino, Hirokazu Tanaka, Christelle Harly, Risa Chihara, Yasuyo Harada, Sawako Muroi, Masato Kubo, Hidetaka Kosako, Ichiro Taniuchi
Publikováno v:
The Journal of Immunology. 210:1728-1739
Posttranslational modification, such as phosphorylation, is an important biological event that modulates and diversifies protein function. Bcl11b protein is a zinc-finger transcription factor that plays a crucial role in early T cell development and
Autor:
Kazuki Okuyama, Keitaro Yamaguchi, Keita Atsuumi, Kazuhiro Matsui, Hiroaki Hirai, Atsushi Nishikawa, Kazuhiro Taniguchi
Publikováno v:
Journal of the Robotics Society of Japan. 40:841-844
Autor:
Osamu Ohara, Tomohiro Morio, Hirokazu Kanegane, Naoki Shimojo, Ichiro Taniuchi, Noriko Mitsuiki, Sergio D. Rosenzweig, Hye Sun Kuehn, Kam Y. J. Zhang, Masatoshi Takagi, Kazuki Okuyama, Motoi Yamashita, Jean-Laurent Casanova, Aditya K. Padhi, Yuzaburo Inoue, Kohsuke Imai, Miyuki Tsumura, Satoshi Okada, Bertrand Boisson, Masahiro Takeuchi
Publikováno v:
Nat Immunol
In the present study, we report a human-inherited, impaired, adaptive immunity disorder, which predominantly manifested as a B cell differentiation defect, caused by a heterozygous IKZF3 missense variant, resulting in a glycine-to-arginine replacemen