Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kazuki Ojino"'
Autor:
Yukimichi Nakano, Masamitsu Shimazawa, Kazuki Ojino, Hiroshi Izawa, Hiroto Takeuchi, Yuki Inoue, Kazuhiro Tsuruma, Hideaki Hara
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 3, Pp 176-183 (2017)
Toll-like receptor 4 (TLR4) plays key roles in innate immune responses and inflammatory reactions. TAK-242 (resatorvid) is a small-molecule cyclohexene derivative that selectively inhibits TLR4 signaling pathways and suppresses inflammatory reactions
Externí odkaz:
https://doaj.org/article/96a8f6bf4b274bee952db91e1b4fd1e7
Autor:
Masamitsu Shimazawa, Yukimichi Nakano, Kyoko Ishida, Satoshi Inagaki, Kazuhide Kawase, Tetsuya Yamamoto, Tomohiro Otsuka, Kazuki Ojino, Hideaki Hara
Publikováno v:
Ophthalmic Research. 64:68-76
The characteristics of the conjunctival bleb are some of the most important factors for the surgical success of glaucoma filtering surgery. To improve surgical outcome, we investigated bleb histology after 3 different glaucoma surgeries. Surgery was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87bab09d2a66a247b8e8ea5e8917b74
https://doi.org/10.1159/000509135
https://doi.org/10.1159/000509135
Autor:
Yuki Inoue, Kazuhiro Tsuruma, Masamitsu Shimazawa, Takashi Ishibashi, Hiroshi Izawa, Yusuke Nakano, Tomohiro Otsuka, Kazuki Ojino, Hideaki Hara
Publikováno v:
Current Eye Research. 41:1465-1472
Astaxanthin exhibits various pharmacological activities, including anti-oxidative, anti-tumor, and anti-inflammatory effects, and is thought to exert a neuroprotective effect via these mechanisms. The purpose of this study was to investigate the prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087db15db2a1db0dce55492ae3ce03ac
https://doi.org/10.3109/02713683.2015.1127392
https://doi.org/10.3109/02713683.2015.1127392
Autor:
Masamitsu Shimazawa, Hiroshi Izawa, Hideaki Hara, Kazuki Ojino, Yukimichi Nakano, Kazuhiro Tsuruma
Publikováno v:
Journal of Neuroscience Research. 93:1675-1683
DBA/2J mice are one of several animal strains used for experimental models of both intraocular hypertension and glaucoma. This study investigates the relationship between endoplasmic reticulum (ER) stress and optic nerve degeneration in DBA/2J mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b6da69566144ccec5033931e2c1dfc1
https://doi.org/10.1002/jnr.23630
https://doi.org/10.1002/jnr.23630
Autor:
Hideaki Hara, Masamitsu Shimazawa, Tomohiro Otsuka, Kazuki Ojino, Yuta Ohno, Kazuhiro Tsuruma
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:424-430
Although dry age-related macular degeneration (AMD) is one of the major causes of blindness, no effective therapies are developed. In this study, we investigated the effects of SUN N8075, a radical scavenger with neuroprotective properties, against l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4822f049c800462ac80d81df7f986be9
https://doi.org/10.1248/bpb.b13-00778
https://doi.org/10.1248/bpb.b13-00778
Autor:
Yukimichi Nakano, Hiroto Takeuchi, Kazuki Ojino, Masamitsu Shimazawa, Hideaki Hara, Kazuhiro Tsuruma, Hiroshi Izawa, Yuki Inoue
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 3, Pp 176-183 (2017)
Toll-like receptor 4 (TLR4) plays key roles in innate immune responses and inflammatory reactions. TAK-242 (resatorvid) is a small-molecule cyclohexene derivative that selectively inhibits TLR4 signaling pathways and suppresses inflammatory reactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e80f51c5a4f9acd4a135699d06703e6
https://pubmed.ncbi.nlm.nih.gov/28318829
https://pubmed.ncbi.nlm.nih.gov/28318829
Autor:
Yuta Ohno, Hideaki Hara, Kazuki Ojino, Masamitsu Shimazawa, Kazuhiro Tsuruma, Hiroshi Izawa, Yuki Inoue
Publikováno v:
Investigative ophthalmologyvisual science. 56(11)
Purpose Placental growth factor (PlGF) is part of the VEGF family and is known to be involved in angiogenesis, vasopermeability, and neuroprotection. Recently, PlGF has been reported as a novel therapeutic target for wet AMD. However, there are few r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c157298e167d6fd0a72079695c2c33b7
https://pubmed.ncbi.nlm.nih.gov/26513607
https://pubmed.ncbi.nlm.nih.gov/26513607
Autor:
Kazuki, Ojino, Masamitsu, Shimazawa, Hiroshi, Izawa, Yukimichi, Nakano, Kazuhiro, Tsuruma, Hideaki, Hara
Publikováno v:
Journal of neuroscience research. 93(11)
DBA/2J mice are one of several animal strains used for experimental models of both intraocular hypertension and glaucoma. This study investigates the relationship between endoplasmic reticulum (ER) stress and optic nerve degeneration in DBA/2J mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05dc596b2edb7f2c31fdb025241dbaeb
https://pubmed.ncbi.nlm.nih.gov/26271210
https://pubmed.ncbi.nlm.nih.gov/26271210