Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kazuki Obashi"'
Autor:
Lisi Wei, Xiaoli Guo, Ehud Haimov, Kazuki Obashi, Sung Hoon Lee, Wonchul Shin, Min Sun, Chung Yu Chan, Jiansong Sheng, Zhen Zhang, Ammar Mohseni, Sudhriti Ghosh Dastidar, Xin-Sheng Wu, Xin Wang, Sue Han, Gianvito Arpino, Bo Shi, Maryam Molakarimi, Jessica Matthias, Christian A. Wurm, Lin Gan, Justin W. Taraska, Michael M. Kozlov, Ling-Gang Wu
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-24 (2024)
Abstract Membrane budding, which underlies fundamental processes like endocytosis, intracellular trafficking, and viral infection, is thought to involve membrane coat-forming proteins, including the most observed clathrin, to form Ω-shape profiles a
Externí odkaz:
https://doaj.org/article/518300501f89466182891e0cc4c55801
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Conformational changes within proteins are thought to regulate clathrin-mediated endocytosis. Here, authors develop a correlative FRET and EM imaging method and uncover a structural switch in clathrin light chain that controls endocytosis in cells.
Externí odkaz:
https://doaj.org/article/8f5004deffaa43619a844e078d9a0cbe
Autor:
Yutaro Kashiwagi, Takahito Higashi, Kazuki Obashi, Yuka Sato, Noboru H. Komiyama, Seth G. N. Grant, Shigeo Okabe
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
We are currently short of methods that can extract objective parameters of dendritic spines useful for their categorization. Authors present in this study an automatic analytical pipeline for spine geometry using 3D-structured illumination microscopy
Externí odkaz:
https://doaj.org/article/fcb3e4a8bb354bfc924d12f963256112
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1503-1515.e8 (2019)
Summary: The biochemical transduction of excitatory synaptic signals occurs in the cytoplasm within dendritic spines. The associated reaction kinetics are shaped by the mobility of the signaling molecules; however, accurate monitoring of diffusional
Externí odkaz:
https://doaj.org/article/24d51b96abda4761ae3aced2e49be39e
The conformations of endocytic proteins and their interactions are key regulators of clathrin-mediated endocytosis. Three clathrin light chains (CLC), along with three clathrin heavy chains, assemble to form single clathrin triskelia that link into a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964d2888b7bcab3bf63f698b6d6ce54d
https://doi.org/10.1101/2022.03.21.485138
https://doi.org/10.1101/2022.03.21.485138
Publikováno v:
European Journal of Neuroscience. 51:806-821
Actin organization and dynamics are modulated by diverse actin regulators during dendritic spine development. To understand the molecular network that regulates actin organization and spine morphology, it is important to investigate dynamic redistrib
Publikováno v:
The Journal of General Physiology
Obashi et al. review the regulation of molecular diffusion by dendritic spine structures and discuss its role in synaptic functions and plasticity.
Spines are tiny nanoscale protrusions from dendrites of neurons. In the cortex and hippocampus, m
Spines are tiny nanoscale protrusions from dendrites of neurons. In the cortex and hippocampus, m
Publikováno v:
Biophysical Journal. 121:228a
Autor:
Shigeo Okabe, Kazuki Obashi
Publikováno v:
Neuromethods ISBN: 9781071605318
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dff5a3e93e34879f503bf336e8f80d51
https://doi.org/10.1007/978-1-0716-0532-5_15
https://doi.org/10.1007/978-1-0716-0532-5_15
Autor:
Seth G. N. Grant, Shigeo Okabe, Yutaro Kashiwagi, Yuka Sato, Kazuki Obashi, Takahito Higashi, Noboru H. Komiyama
Publikováno v:
Kashiwagi, Y, Higashi, T, Obashi, K, Sato, Y, Komiyama, N H, Grant, S G N & Okabe, S 2019, ' Computational geometry analysis of dendritic spines by structured illumination microscopy ', Nature Communications, vol. 10, no. 1 . https://doi.org/10.1038/s41467-019-09337-0
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Dendritic spines are the postsynaptic sites that receive most of the excitatory synaptic inputs, and thus provide the structural basis for synaptic function. Here, we describe an accurate method for measurement and analysis of spine morphology based