Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Kazuki N. Sugahara"'
Autor:
Valeria Sidorenko, Pablo Scodeller, Ain Uustare, Ivan Ogibalov, Andrus Tasa, Olga Tshubrik, Liis Salumäe, Kazuki N. Sugahara, Lorena Simón-Gracia, Tambet Teesalu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Cancer treatment with vascular disrupting agents (VDAs) causes rapid and extensive necrosis in solid tumors. However, these agents fall short in eliminating all malignant cells, ultimately leading to tumor regrowth. Here, we investigated whe
Externí odkaz:
https://doaj.org/article/c2c0fe2679b5496d819101b030d83b28
Autor:
Tatiana Hurtado de Mendoza, Evangeline S. Mose, Gregory P. Botta, Gary B. Braun, Venkata R. Kotamraju, Randall P. French, Kodai Suzuki, Norio Miyamura, Tambet Teesalu, Erkki Ruoslahti, Andrew M. Lowy, Kazuki N. Sugahara
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The iRGD tumor-penetrating peptide can achieve tumor specific drug delivery but whether and how it can penetrate into desmoplastic tumors is unknown. Here, the authors show that β5 integrin expression on tumor cells, mediated by CAFs-derived TGF-β,
Externí odkaz:
https://doaj.org/article/80f9f85745054067b544050e7b18b670
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The imaging of tumors in vivo using nanoprobes has been challenging due to the lack of sufficient tumor specificity. Here, the authors develop a tumor-specific quantum dot system that permits in vivo cation exchange to achieve selective background qu
Externí odkaz:
https://doaj.org/article/4d743ca645be4dcdb910f31cf2136739
Publikováno v:
Frontiers in Oncology, Vol 3 (2013)
Tumor-homing peptides can be used to deliver drugs into tumors. Phage library screening in live mice has recently identified homing peptides that specifically recognize the endothelium of tumor vessels, extravasate, and penetrate deep into the extrav
Externí odkaz:
https://doaj.org/article/14982c330f0c49dc9e39ee9d549dba60
Autor:
Norio Miyamura, Kodai Suzuki, Richard A. Friedman, Aristidis Floratos, Yuki Kunisada, Kazuya Masuda, Andrew M. Lowy, Moriya Tsuji, Kazuki N. Sugahara
Publikováno v:
bioRxiv
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a tumor immune microenvironment (TIME) that promotes resistance to immunotherapy. A preclinical model system that facilitates studies of the TIME and its impact on the responsiveness of huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920cf6fa18125502171290de8b951228
https://europepmc.org/articles/PMC10245824/
https://europepmc.org/articles/PMC10245824/
Autor:
Kodai Suzuki, Yuki Kunisada, Norio Miyamura, Shingo Eikawa, Tatiana Hurtado de Mendoza, Evangeline S. Mose, Caisheng Lu, Yukihito Kuroda, Erkki Ruoslahti, Andrew M. Lowy, Kazuki N. Sugahara
Publikováno v:
bioRxiv
Pancreatic ductal adenocarcinoma (PDAC) has abundant immunosuppressive regulatory T cells (Tregs), which contribute to a microenvironment resistant to immunotherapy. Here, we report that Tregs in the PDAC tissue, but not those in the spleen, express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f870dab7343d7d439753fca69483be8
https://europepmc.org/articles/PMC10245898/
https://europepmc.org/articles/PMC10245898/
Autor:
Anna S. Koerner, Alexander S. Thomas, John A. Chabot, Michael D. Kluger, Kazuki N. Sugahara, Beth A. Schrope
Publikováno v:
Journal of Gastrointestinal Surgery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cdbc7e28a7217e98b18704a103c9416
https://doi.org/10.1007/s11605-023-05693-x
https://doi.org/10.1007/s11605-023-05693-x
Autor:
Erkki Ruoslahti, Tambet Teesalu, Andrew M. Lowy, Randall P. French, Venkata Ramana Kotamraju, Tatiana Hurtado de Mendoza, Gary B. Braun, Kazuki N. Sugahara
Supplementary Movie SM5. Tumor cell migration on plain silver nanoparticles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0943ca5fb463016045888befba83a18c
https://doi.org/10.1158/1535-7163.22501803.v1
https://doi.org/10.1158/1535-7163.22501803.v1
Autor:
Erkki Ruoslahti, Tambet Teesalu, Andrew M. Lowy, Randall P. French, Venkata Ramana Kotamraju, Tatiana Hurtado de Mendoza, Gary B. Braun, Kazuki N. Sugahara
Supplementary Figures 1-7. Supplemental Figure 1: Metastatic burden and primary tumor weight after long term in vivo peptide treatment Supplemental Figure 2: In vitro and in vivo targeting of pancreatic tumor cells by iRGD and iNGR Supplemental Figur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e514fc2924b8e12dc638301fb911a40
https://doi.org/10.1158/1535-7163.22501815
https://doi.org/10.1158/1535-7163.22501815
Autor:
Erkki Ruoslahti, Tambet Teesalu, Andrew M. Lowy, Randall P. French, Venkata Ramana Kotamraju, Tatiana Hurtado de Mendoza, Gary B. Braun, Kazuki N. Sugahara
Supplemental Table 1. Summary of statistical analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2362d32b56d2fe42ab157fcb8936bc7e
https://doi.org/10.1158/1535-7163.22501818
https://doi.org/10.1158/1535-7163.22501818