Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Kazuki Mochizuki"'
Autor:
Shiori Ishiyama, Manabu Hayatsu, Taku Toriumi, Hiromasa Tsuda, Keisuke Watanabe, Hirotake Kasai, Satoshi Kishigami, Kazuki Mochizuki, Yoshikazu Mikami
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Non-alcoholic steatohepatitis (NASH), caused by fat buildup, can lead to liver inflammation and damage. Elucidation of the spatial distribution of fibrotic tissue in the fatty liver in NASH can be immensely useful to understand its pathogene
Externí odkaz:
https://doaj.org/article/1eaae173d9934f5c890b271e0aaecee5
Autor:
Shiori Ishiyama, Kazuki Mochizuki, Ryoji Shinohara, Kunio Miyake, Megumi Kushima, Reiji Kojima, Sayaka Horiuchi, Sanae Otawa, Hideki Yui, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata, The Japan Environment and Children’s Study Group
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Hypertensive disorders of pregnancy (HDP) increase the risk of preterm births and cesarean delivery. This study aimed to investigate whether maternal blood leukocyte, monocyte, or neutrophil counts in the first trimester are related to the d
Externí odkaz:
https://doaj.org/article/d3dd68baefc44fe08e8cbabeca3fa6da
Autor:
Yuji Tanaka, Naana Baba-Mori, Takaaki Yonaga, Kazuki Mochizuki, Satoshi Igarashi, Takashi Ando, Takashi Kohda, Yasumi Ito, Kenzo Soejima, Daiju Sakurai
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
Obesity and ageing are the most important risk factors for sleep apnoea syndrome (SAS); however, the role of body mass index (BMI) on sleep status in healthy older adults is unclear. To explore sleep parameters according to BMI among active older adu
Externí odkaz:
https://doaj.org/article/f857a83f084b4e5d816bf8c876bb0110
Autor:
Kunio Miyake, Sayaka Horiuchi, Ryoji Shinohara, Megumi Kushima, Sanae Otawa, Hideki Yui, Yuka Akiyama, Tadao Ooka, Reiji Kojima, Hiroshi Yokomichi, Kazuki Mochizuki, Zentaro Yamagata, The Japan Environment Children's Study Group, Michihiro Kamijima, Shin Yamazaki, Yukihiro Ohya, Reiko Kishi, Nobuo Yaegashi, Koichi Hashimoto, Chisato Mori, Shuichi Ito, Hidekuni Inadera, Takeo Nakayama, Tomotaka Sobue, Masayuki Shima, Hiroshige Nakamura, Narufumi Suganuma, Koichi Kusuhara, Takahiko Katoh
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
BackgroundAnimal studies have shown that maternal low-fiber diets during pregnancy may impair brain development and function in offspring, but this has not been validated by epidemiological studies. The aim of this study was to investigate the link b
Externí odkaz:
https://doaj.org/article/0049d0a650844abcbedda420d6877be6
Publikováno v:
Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101475- (2023)
Background: It remains unclear whether goblet cell numbers in offspring are altered by maternal nutritional status and/or early weaning. Herein, using a murine model, we clarified whether a low-protein (LP) diet during pregnancy and/or early weaning
Externí odkaz:
https://doaj.org/article/4b4771cb4542434fba4629efa55fa6ab
Autor:
Yuji Tanaka, Takashi Ando, Kazuki Mochizuki, Satoshi Igarashi, Kyoichiro Tsuchiya, Kozo Saito, Yasumi Ito, Zentaro Yamagata, Masaru Iwasaki, YHAB Health Data Survey Group
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Study Objectives: Aging is a risk factor for sleep apnoea syndrome (SAS), which is associated with lower quality of life and sudden mortality. However, SAS is often overlooked in older adults without suspicions. Therefore, this study aimed to evaluat
Externí odkaz:
https://doaj.org/article/460530c0b5964796a244766c75b1256b
Publikováno v:
Biochemistry and Biophysics Reports, Vol 31, Iss , Pp 101325- (2022)
β-Carotene is converted into vitamin A in the body and can remove reactive oxygen species. However, it is still unclear whether β-carotene alters the expression levels of inflammation-related genes in macrophages and how this is regulated. In the p
Externí odkaz:
https://doaj.org/article/53347446e7654219ac5236c08414750c
Autor:
Musashi Kawamura, Naoki Goda, Natsuyo Hariya, Mayu Kimura, Shiori Ishiyama, Takeo Kubota, Kazuki Mochizuki
Publikováno v:
Biochemistry and Biophysics Reports, Vol 29, Iss , Pp 101196- (2022)
Background: The expressions of genes related to lipid metabolism are decreased in adipocytes with insulin resistance. In this study, we examined the effects of fatty acids on the reduced expressions and histone acetylation of lipid metabolism-related
Externí odkaz:
https://doaj.org/article/9fd0453fd3444a699fa0adb7825fa65f
Autor:
Misako Suzuki, Yukiko Kohmura-Kobayashi, Megumi Ueda, Naomi Furuta-Isomura, Masako Matsumoto, Tomoaki Oda, Kenta Kawai, Toshiya Itoh, Madoka Matsuya, Megumi Narumi, Naoaki Tamura, Toshiyuki Uchida, Kazuki Mochizuki, Hiroaki Itoh
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Rapid infantile growth (RG) markedly increases the risk of obesity and metabolic disorders in adulthood, particularly among neonates born small. To elucidate the molecular mechanisms by which RG following undernourishment in utero (UN) contributes to
Externí odkaz:
https://doaj.org/article/cf58e3244744472c869fcc44337e2f44
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Background At its earliest stages, mammalian embryonic development is apparently simple but vulnerable. The environment during the preimplantation period, which only lasts a couple of days, has been implicated in adult health, extending to s
Externí odkaz:
https://doaj.org/article/fe134de8cdb54726a6f15fa88a61a834