Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kazuki Kuroshima"'
Autor:
Shunsuke Okamura, Hirofumi Yoshino, Kazuki Kuroshima, Masafumi Tsuruda, Yoichi Osako, Takashi Sakaguchi, Masaya Yonemori, Yasutoshi Yamada, Shuichi Tatarano, Masayuki Nakagawa, Hideki Enokida
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Cisplatin-based chemotherapy is recommended as the primary treatment for advanced bladder cancer (BC) with unresectable or metastatic disease. However, the benefits are limited due to the acquisition of drug resistance. The mechan
Externí odkaz:
https://doaj.org/article/6feac8a317494b429e34a1d75459308a
Autor:
Hirofumi Yoshino, Hideki Enokida, Yoichi Osako, Nijiro Nohata, Masaya Yonemori, Satoshi Sugita, Kazuki Kuroshima, Masafumi Tsuruda, Shuichi Tatarano, Masayuki Nakagawa
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 2190-2202 (2020)
d‐3‐Phosphoglycerate dehydrogenase (PHGDH) conducts an important step in the synthesis of serine. Importantly, the PHGDH gene is often amplified in certain cancers. Our previous studies revealed that PHGDH gene amplification was associated with p
Externí odkaz:
https://doaj.org/article/6530e96752de42b3bae1dec28ec466d0
Autor:
Masafumi Tsuruda, Hirofumi Yoshino, Shunsuke Okamura, Kazuki Kuroshima, Yoichi Osako, Takashi Sakaguchi, Satoshi Sugita, Shuichi Tatarano, Masayuki Nakagawa, Hideki Enokida
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232545 (2020)
Exosomes are 40-100 nm nano-sized extracellular vesicles. They are released from many cell types and move into the extracellular space, thereby transferring their components to recipient cells. Exosomes are receiving increasing attention as novel str
Externí odkaz:
https://doaj.org/article/d0675909cb614a63a521ce7ed26c434f
Autor:
Hirofumi Yoshino, Yasutoshi Yamada, Hideki Enokida, Yoichi Osako, Masafumi Tsuruda, Kazuki Kuroshima, Takashi Sakaguchi, Satoshi Sugita, Shuichi Tatarano, Masayuki Nakagawa
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236119 (2020)
The alcohol-abuse drug disulfiram has antitumor effects against diverse cancer types via inhibition of the ubiquitin-proteasome protein nuclear protein localization protein 4 (NPL4). However, the antitumor effects of NPL4 and disulfiram in clear cell
Externí odkaz:
https://doaj.org/article/498d50e7cdcd4fc3af5daabc2847815c
Autor:
Masafumi Tsuruda, Yoichi Osako, Masaya Yonemori, Hirofumi Yoshino, Satoshi Sugita, Nijiro Nohata, Kazuki Kuroshima, Shuichi Tatarano, Hideki Enokida, Masayuki Nakagawa
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 14, Iss 9, Pp 2190-2202 (2020)
Molecular Oncology, Vol 14, Iss 9, Pp 2190-2202 (2020)
d‐3‐Phosphoglycerate dehydrogenase (PHGDH) conducts an important step in the synthesis of serine. Importantly, the PHGDH gene is often amplified in certain cancers. Our previous studies revealed that PHGDH gene amplification was associated with p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7835e3f6a353b1aefb0aaad110bd141
http://europepmc.org/articles/PMC7463350
http://europepmc.org/articles/PMC7463350
Autor:
Yasutoshi Yamada, Hirofumi Yoshino, Takashi Sakaguchi, Masaya Yonemori, Masafumi Tsuruda, Shunsuke Okamura, Hideki Enokida, Kazuki Kuroshima, Masayuki Nakagawa, Shuichi Tatarano, Yoichi Osako
Publikováno v:
BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Background Cisplatin-based chemotherapy is recommended as the primary treatment for advanced bladder cancer (BC) with unresectable or metastatic disease. However, the benefits are limited due to the acquisition of drug resistance. The mechanisms of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fed8c04f55698c2ccff8c3bf0096c2e
http://europepmc.org/articles/PMC7798329
http://europepmc.org/articles/PMC7798329
Autor:
Hideki Enokida, Masafumi Tsuruta, Masaya Yonemori, Hirofumi Yoshino, Masayuki Nakagawa, Yoichi Osako, Kazuki Kuroshima
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:Molecular targeted drugs that can inhibit vascular endothelial growth factor receptor (VEGFR), mammalian target of rapamycin (mTOR), or programmed cell death 1 (PD-1) hav...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd6d139e78f11d518fc26c7465c66f1f
https://doi.org/10.1097/ju.0000000000000981.05
https://doi.org/10.1097/ju.0000000000000981.05
Autor:
Shunsuke Okamura, Hideki Enokida, Kazuki Kuroshima, Hirofumi Yoshino, Yoichi Osako, Shuichi Tatarano, Masafumi Tsuruda, Masayuki Nakagawa
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:Exosomes are 40-100 nm nano-sized extracellular vesicles, released from many cell types and transfer their component to recipient cells. Recently exosomes have received i...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::345ae26c0f9f8d5626bf98fb0864da7e
https://doi.org/10.1097/ju.0000000000000843.012
https://doi.org/10.1097/ju.0000000000000843.012
Autor:
Hideki Enokida, Shunsuke Okamura, Masayuki Nakagawa, Kazuki Kuroshima, Masafumi Tsuruda, Shuichi Tatarano, Hirofumi Yoshino, Yoichi Osako
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:Temsirolimus and Everolimus, termed rapalogs, have been used as first generation mTOR inhibitors for renal cell carcinoma (RCC). These rapalogs were designed to block onl...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e9f64aa240c6abdf2289025f1bcc6ad
https://doi.org/10.1097/ju.0000000000000843.016
https://doi.org/10.1097/ju.0000000000000843.016
Autor:
Takashi Sakaguchi, Hideki Enokida, Hirofumi Yoshino, Kazuki Kuroshima, Masafumi Tsuruda, Yasutoshi Yamada, Masayuki Nakagawa, Satoshi Sugita, Shuichi Tatarano, Yoichi Osako
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236119 (2020)
PLoS ONE
PLoS ONE
The alcohol-abuse drug disulfiram has antitumor effects against diverse cancer types via inhibition of the ubiquitin-proteasome protein nuclear protein localization protein 4 (NPL4). However, the antitumor effects of NPL4 and disulfiram in clear cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b29fa2033b669efcd0fdd6bc3569c6
https://doaj.org/article/498d50e7cdcd4fc3af5daabc2847815c
https://doaj.org/article/498d50e7cdcd4fc3af5daabc2847815c